Adenosine A2b Receptor (ADORA2B) Goat Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC
Recommend Dilution	WB: 1ug/ml; IHC: 2-4ug/ml.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence CQADVKSGNGQ, from the C Terminus of the protein sequence according to NP_000667.1.
Formulation	0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Concentration	lot specific
Purification	Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	adenosine A2b receptor
Database Link	NP_000667 Entrez Gene 136 Human UniProt ID P29275
Background	This gene encodes an adenosine receptor that is a member of the G protein-coupled receptor superfamily. This integral membrane protein stimulates adenylate cyclase activity in the presence of adenosine. This protein also interacts with netrin-1, which is involved in axon elongation. The gene is located near the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq]
Synonyms	ADORA2
Note	In paraffin embedded Human Kidney shows cytoplasm staining in cells of renal tubules .
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Calcium signaling pathway, Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction

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