YAP1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, ICC/IF, IHC, Immunoblotting, IP, Simple Western, WB
Recommend Dilution	Western Blot: 1:1000, Simple Western: 1:12.5, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry: 1:50-1:200, Immunohistochemistry-Paraffin: 1:50-1:200, Immunoprecipitation: 2-10 ug, Immunoblotting, Chromatin Immunoprecipitation (ChIP), Knockout Validated, Knockdown Validated, Immunohistochemistry-Frozen
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant YAP protein expressed in bacteria.
Formulation	PBS, 15% glycerol and 0.02% sodium azide
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	Yes associated protein 1
Database Link	NP_006097 Entrez Gene 10413 Human UniProt ID P46937
Background	YAP (Yes-Associated Protein) is a founding member of the WW domain family of proteins, transcriptional co-activator and oncogene. Its gene is transcriptionally activated in squamous cell carcinoma cells. As one of several genes of 1q22 amplicon, YAP was recently implicated in liver and breast cancer. Overexpression of YAP gene in MCF10A mammary cell line induces oncogenic transformation.
Synonyms	COB1; YAP; YAP2; YAP65; YKI
Reference Data
Protein Families	Druggable Genome

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