CD9 Mouse Monoclonal Antibody [Clone ID: MM2/57]

Specifications

Product Data
Clone Name	MM2/57
Applications	FC, IHC, WB
Recommend Dilution	Western Blot.  Flow Cytometry: Use 10 µl of 1/100-1/200 diluted antibody to label 106 cells or 100 µl whole blood. Immunohistochemistry on Frozen Sections: 1/500-1/1000.
Reactivity	Bovine, Canine, Equine, Feline, Human, Rabbit
Host	Mouse
Clonality	Monoclonal
Immunogen	Human platelet membrane. Spleen cells from BALB/c mice immunised were fused with cells of the mouse SP2/0 myeloma line.
Specificity	This antibody clone MM2/57 recognizes a conserved epitope on CD9 present on wide range of mammalian species.
Formulation	PBS State: Purified State: Liquid purified IgG fraction Preservative: 0.09% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein G
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	CD9 molecule
Database Link	Entrez Gene 928 Human UniProt ID P21926
Background	CD9 is a member of the tetraspan gene family. CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. It belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. In pre B cells and platelets, CD9 antigen regulates cell activation and aggregation possibly through an association with the integrin CD41 / CD61 (GPIIb / GPIIIa). It also regulates cell motility in a variety of cell lines, and appears to be an important regulator of Schwann cell behaviour in peripheral nerve.
Synonyms	MIC3, TSPAN29, GIG2, p24, Tetraspanin-29, 5H9 antigen
Reference Data

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