SIL1 Mouse Monoclonal Antibody [Clone ID: OTI3B11]

Specifications

Product Data
Clone Name	OTI3B11
Applications	FC, IF, IHC, WB
Recommend Dilution	WB 1:500, IHC 1:50, IF 1:100, Flow 1:100
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SIL1 (NP_071909) produced in HEK293T cell.
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	52.1 kDa
Gene Name	SIL1 nucleotide exchange factor
Database Link	NP_071909 Entrez Gene 291673 RatEntrez Gene 64374 Human UniProt ID Q9H173
Background	This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
Synonyms	BAP; MSS; ULG5
Reference Data
Protein Families	Protease, Secreted Protein, Transmembrane

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