Osteopontin (SPP1) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: 1:1000  Immunofluorescence: 1:25 Immunohistochemistry on Paraffin Sections: 1:50~100
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 14-40 amino acids from the N-terminal region of Human Osteopontin (OPN-a/b)
Specificity	This antibody recognizes Human Osteopontin (OPN-a/b) (N-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	secreted phosphoprotein 1
Database Link	Entrez Gene 6696 Human UniProt ID P10451
Background	Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).
Synonyms	BNSP, OPN, SPP-1, Nephropontin, Uropontin
Note	Molecular Weight: 35423 Da
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway

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