LOC102723996 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000.  Western Blot: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 216-246 amino acids from the C-terminal region of human CD275 / ICOS Ligand
Specificity	This antibody recognizes Human CD275 / ICOS Ligand (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ICOS ligand
Database Link	Entrez Gene 23308 HumanEntrez Gene 102723996 Human UniProt ID O75144
Background	Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).
Synonyms	B7 homolog 2, B7-like protein Gl50, B7-related protein 1, ICOSLG, B7H2, B7RP1, B7RP-1, ICOSL, KIAA0653
Note	Molecular Weight: 33349 Da
Reference Data
Protein Families	Transmembrane
Protein Pathways	Cell adhesion molecules (CAMs)

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