Adcy3 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western Blot: 1/2000.  Immunohistochemistry. Immunofluorescence: 1/500.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to amino acid residues from the C-terminal region of Rat Adenylate Cyclase III conjugated to KLH.
Specificity	Specific for the ~160 kDa Adenylate Cyclase III.
Formulation	PBS State: Aff - Purified State: Liquid purified IgG fraction
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Upon receipt, store undiluted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	adenylate cyclase 3
Database Link	Entrez Gene 64508 Rat UniProt ID P21932
Background	Adenylate cyclase is the enzyme which produces the “second messenger” signaling molecule, cAMP from ATP. Type III adenylate cyclase is localized to the membranes surrounding neuronal cilia. Much is currently unknown about the function of primary cilia in vertebrates, however, recent work has begun to explore their role in neuronal signaling and neurogenesis (Fuchs and Schwark, 2004; Louvi and Grove 2011).
Synonyms	ADCY3, KIAA0511, Adenylate cyclase type III, ATP pyrophosphate-lyase 3, Adenylyl cyclase 3
Reference Data

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