TRF41 (PAPD7) (447-462) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1 - 2 µg/ml.
Reactivity	Human, Monkey
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide containing amino acids 447-462 of human TRF4-1
Specificity	This antibody recognizes Polymerase (DNA Directed) Sigma (POLS/TRF4-1) at aa 447-462.
Formulation	PBS containing 0.2% Gelatin as stabilizer and 0.05% Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein G Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	PAP associated domain containing 7
Database Link	Entrez Gene 11044 Human UniProt ID Q5XG87
Background	Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.
Synonyms	DNA polymerase sigma, DNA polymerase kappa, TRF-4, LAK-1, TUTase5
Reference Data

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