IL6R Mouse Monoclonal Antibody [Clone ID: B-R6]

Specifications

Product Data
Clone Name	B-R6
Applications	FC, FN, IHC, IP
Recommend Dilution	ELISA.  Flow Cytometry. Immunoprecipitation. Immunohistochemistry on Frozen Sections. Functional Assay: Blocks IL-6 induced proliferation of XG-1 cells. Inhibits IL-6 binding to its receptor.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	gp80 transfected CHO cell line
Specificity	This antibody recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein.
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free State: Azide Free State: Liquid purified IgG fraction
Concentration	lot specific
Purification	Ion Exchange Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C.
Gene Name	interleukin 6 receptor
Database Link	Entrez Gene 3570 Human UniProt ID P08887
Synonyms	Interleukin-6 receptor subunit alpha, IL-6R-alpha, IL-6R 1, IL6 Receptor alpha
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway

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