CD28 Mouse Monoclonal Antibody [Clone ID: CD28.2]

CAT#: AM12006PU-N

CD28 mouse monoclonal antibody, clone CD28.2, Purified

Conjugation: Unconjugated APC FITC PE PerCP



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CNY 3,140.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Clone Name CD28.2
Applications FC, FN, IF, IHC, IP, WB
Recommend Dilution Flow cytometry.
Immunoprecipitation.
Western blot.
Immunohistochemistry (frozen sections).
Immunocytochemistry.
Functional application: T cell costimulation.
Reactivity Human, Primate
Host Mouse
Clonality Monoclonal
Immunogen DC28.1.3.3 murine T cell hybridoma transfected with human CD28 cDNA
Specificity This antibody reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
Formulation Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
State: Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein A affinity chromatography; purity > 95% (by SDS-PAGE)
Conjugation Unconjugated
Storage Condition Store undiluted at 2-8°C.
DO NOT FREEZE!
Gene Name CD28 molecule
Background CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
Synonyms TP44
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Graft-versus-host disease, Systemic lupus erythematosus, T cell receptor signaling pathway, Type I diabetes mellitus, Viral myocarditis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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