CDC25A Mouse Monoclonal Antibody [Clone ID: DCS-121]

Specifications

Product Data
Clone Name	DCS-121
Applications	IP, WB
Recommend Dilution	Western Blot. Immunoprecipitation (1-10 ug/ml).
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Purified recombinant CDC25A protein.
Formulation	PBS containing 0.08% Sodium Azide as preservative. State: Purified State: Liquid (sterile filtered) purified IgG fraction.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	cell division cycle 25A
Database Link	Entrez Gene 993 Human UniProt ID P30304
Background	CDC25A recognizes a 65kD protein In the cell cycle of eukaryotes the M phase is initiated by maturation promoting factor (MPF), a protein kinase complex consisting of p34 cdc2, cyclin B, and p13. The activity of this complex is controlled by multiple levels of phosphorylation and dephosphorylation of the catalytic p34cdc2 component. CDC25A and CDC25B arep34cdc2 tyrosine phosphates. Dephosphorylation of p34cdc2 by these CDC25 proteins activates the MPF complex, initiating mitosis. Although expressed throughout the cell cycle, peak expression of CDC25A is in G1 of the cell cycle.
Synonyms	CDC-25A
Reference Data

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