JNK1 (MAPK8) (N-term) (incl. pos. control) Mouse Monoclonal Antibody [Clone ID: 5D10]

Specifications

Product Data
Clone Name	5D10
Applications	ELISA, IHC, WB
Recommend Dilution	Western Blot: 0.5 μg/ml for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubation buffer. Positive Control: Cell lysate from untreated HepG2 cells. ELISA: 0.05 μg/ml. Immunohistochemistry on frozen sections.
Reactivity	Canine, Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide conjugated to KLH.
Specificity	This antibody specifically interacts with the N-terminus of SAPK1γ/jnk1 kinases.
Formulation	PBS/0.09% Na-Azide/PEG and Sucrose Label: Biotin State: Liquid purified IgG
Concentration	lot specific
Purification	Size exclusion chromatography
Conjugation	Biotin
Storage Condition	Store the antibody (aliquote in liquid nitrogen) at -80°C. Avoid repeated freezing and thawing. Thaw aliquots at 37°C. Thawed aliquots may be stored at 4°C up to 3 months.
Gene Name	mitogen-activated protein kinase 8
Database Link	Entrez Gene 5599 Human UniProt ID P45983
Background	Stress-activated Protein Kinases (SAPKs) are strongly activated in response to adverse stimuli such as heat and osmotic shock, UV light and other DNA-damaging reagents, and inhibitors of protein synthesis. They are also activated strongly in response to agonists that are released or produced under conditions of stress, such as proinflammatory cytokines. The SAPK1/jnk family consists of 3 isoforms: SAPK1α/jnk2; SAPK1β/jnk3; SAPK1γ/jnk1.
Synonyms	Mitogen-activated protein kinase 8, c-Jun N-terminal kinase 1, JNK-46, JNK-1, PRKM8
Reference Data

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