IDH2 mutant (R172G), Myc-DDK-tagged ORF clone of Homo sapiens isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2), nuclear gene encoding mitochondrial protein as transfection-ready DNA
| Mutation | R172G |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Mutant ORF Clones
ILK Mutant (A262V), Myc-DDK-tagged ORF clone of Homo sapiens integrin-linked kinase (ILK), transcript variant 1 as transfection-ready DNA
| Mutation | A262V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (A2T), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | A2T |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH6 Mutant (A20V), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 6 (E. coli) (MSH6) as transfection-ready DNA
| Mutation | A20V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CTNNB1 Mutant (S33P), Myc-DDK-tagged ORF clone of Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 as transfection-ready DNA
| Mutation | S33P |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
EPHX1 Mutant (R43T), Myc-DDK-tagged ORF clone of Homo sapiens epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1 as transfection-ready DNA
| Mutation | R43T |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
HIF1A Mutant (P582S), Myc-DDK-tagged ORF clone of Homo sapiens hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A), transcript variant 1 as transfection-ready DNA
| Mutation | P582S |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
GPC3 Mutant (C65X), Myc-DDK-tagged ORF clone of Homo sapiens glypican 3 (GPC3), transcript variant 2 as transfection-ready DNA
| Mutation | C65X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (Q62K), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | Q62K |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CSF1R Mutant (Y969C), Myc-DDK-tagged ORF clone of Homo sapiens colony stimulating factor 1 receptor (CSF1R) as transfection-ready DNA
| Mutation | Y969C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MEN1 Mutant (P12L), Myc-DDK-tagged ORF clone of Homo sapiens multiple endocrine neoplasia I (MEN1), transcript variant 2 as transfection-ready DNA
| Mutation | P12L |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CDKN1B Mutant (W76X), Myc-DDK-tagged ORF clone of Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) as transfection-ready DNA
| Mutation | W76X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
活动过滤器
优化搜索结果
Category
Species
Target Symbol
- ISOCITRATE DEHYDROGENASE (5)
- KRAS (4)
- EGFR (3)
- AKT1 (2)
- BETA CATENIN (2)
- HIF-1 ALPHA (2)
- IDH2 (2)
- P21 RAS (2)
- P53 (2)
- ALK (1)
- B RAF (1)
- CDK4 (1)
- EPOXIDE HYDROLASE (1)
- FGFR4 (1)
- GLYPICAN 3 (1)
- INTEGRIN LINKED KINASE (1)
- MCSF RECEPTOR (1)
- MENIN (1)
- MET (1)
- MLH1 (1)
- MSH2 (1)
- MSH6 (1)
- NRAS (1)
- P27 KIP 1 (1)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (1)
- PTEN (1)
- RET (1)
Tags
Vectors
Mutants
Brands
Families
- Druggable Genome (33)
- Protein Kinase (13)
- ES Cell Differentiation/IPS (7)
- Transcription Factors (7)
- Transmembrane (6)
- Stem cell - Pluripotency (4)
- Adult stem cells (3)
- Cancer stem cells (3)
- Secreted Protein (3)
- Stem cell relevant signaling - JAK/STAT signaling pathway (3)
- Phosphatase (1)
- Protease (1)
Pathways
- Pathways in cancer (29)
- Endometrial cancer (21)
- Prostate cancer (20)
- Colorectal cancer (19)
- Melanoma (19)
- Glioma (18)
- Non-small cell lung cancer (17)
- MAPK signaling pathway (16)
- Chronic myeloid leukemia (15)
- ErbB signaling pathway (15)
- Bladder cancer (14)
- Focal adhesion (14)
- Pancreatic cancer (14)
- Renal cell carcinoma (14)
- Neurotrophin signaling pathway (13)
- Regulation of actin cytoskeleton (13)
- Thyroid cancer (13)
- Tight junction (13)
- Acute myeloid leukemia (11)
- Chemokine signaling pathway (11)
- Insulin signaling pathway (11)
- T cell receptor signaling pathway (11)
- B cell receptor signaling pathway (10)
- Fc epsilon RI signaling pathway (10)
- Gap junction (10)
- GnRH signaling pathway (10)
- VEGF signaling pathway (10)
- Endocytosis (9)
- Melanogenesis (9)
- Natural killer cell mediated cytotoxicity (9)
- Axon guidance (8)
- Long-term depression (8)
- Long-term potentiation (8)
- Progesterone-mediated oocyte maturation (8)
- Small cell lung cancer (8)
- Citrate cycle (TCA cycle) (7)
- Dorso-ventral axis formation (7)
- Glutathione metabolism (7)
- Metabolic pathways (7)
- Adherens junction (6)
- mTOR signaling pathway (6)
- Apoptosis (5)
- Cytokine-cytokine receptor interaction (5)
- Basal cell carcinoma (4)
- Cell cycle (4)
- Epithelial cell signaling in Helicobacter pylori infection (4)
- Wnt signaling pathway (4)
- p53 signaling pathway (4)
- Calcium signaling pathway (3)
- Fc gamma R-mediated phagocytosis (3)
- Jak-STAT signaling pathway (3)
- Leukocyte transendothelial migration (3)
- Mismatch repair (3)
- Toll-like receptor signaling pathway (3)
- Adipocytokine signaling pathway (2)
- Amyotrophic lateral sclerosis (ALS) (2)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (2)
- Huntington's disease (2)
- Inositol phosphate metabolism (2)
- Pathogenic Escherichia coli infection (2)
- Phosphatidylinositol signaling system (2)
- Hematopoietic cell lineage (1)
- Metabolism of xenobiotics by cytochrome P450 (1)
- PPAR signaling pathway (1)
- Type II diabetes mellitus (1)
- Vascular smooth muscle contraction (1)
