BTK Mutant (W251X), Myc-DDK-tagged ORF clone of Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK) as transfection-ready DNA
| Mutation | W251X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Mutant ORF Clones
PTEN Mutant (F241fs*15), Myc-DDK-tagged ORF clone of Homo sapiens phosphatase and tensin homolog (PTEN) as transfection-ready DNA
| Mutation | F241fs*15 |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (S131X), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | S131X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRCA2 Mutant (S1121X), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA2) as transfection-ready DNA
| Mutation | S1121X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRCA2 Mutant (Y1655X), Myc-DDK-tagged ORF clone of Homo sapiens breast Cancer, early onset (BRCA2) as transfection-ready DNA
| Mutation | Y1655X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BTK Mutant (Y476D), Myc-DDK-tagged ORF clone of Homo sapiens Bruton agammaglobulinemia tyrosine kinase (BTK) as transfection-ready DNA
| Mutation | Y476D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
NF2 Mutant (Q538X), Myc-DDK-tagged ORF clone of Homo sapiens neurofibromin 2 (merlin) (NF2), transcript variant 1 as transfection-ready DNA
| Mutation | Q538X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (M458K), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | M458K |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
FH Mutant (C333Y), Myc-DDK-tagged ORF clone of Homo sapiens fumarate hydratase (FH), nuclear gene encoding mitochondrial protein as transfection-ready DNA
| Mutation | C333Y |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
NOTCH3 Mutant (Y574C), Myc-DDK-tagged ORF clone of Homo sapiens notch 3 (NOTCH3) as transfection-ready DNA
| Mutation | Y574C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (R659X), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | R659X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
FH Mutant (Q185R), Myc-DDK-tagged ORF clone of Homo sapiens fumarate hydratase (FH), nuclear gene encoding mitochondrial protein as transfection-ready DNA
| Mutation | Q185R |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
NF2 Mutant (R196X), Myc-DDK-tagged ORF clone of Homo sapiens neurofibromin 2 (merlin) (NF2), transcript variant 1 as transfection-ready DNA
| Mutation | R196X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH6 Mutant (S702X), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 6 (E. coli) (MSH6) as transfection-ready DNA
| Mutation | S702X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
PTEN Mutant (R130G), Myc-DDK-tagged ORF clone of Homo sapiens phosphatase and tensin homolog (PTEN) as transfection-ready DNA
| Mutation | R130G |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
活动过滤器
优化搜索结果
Species
Target Symbol
- BRCA1 (388)
- BTK (291)
- BRCA2 (273)
- GLUCOKINASE (249)
- TUBERIN (240)
- MENIN (237)
- MLH1 (233)
- MSH2 (212)
- RET (179)
- NOTCH3 (156)
- P53 (122)
- NF2 (87)
- MSH6 (83)
- LKB1 (82)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (67)
- WILMS TUMOR PROTEIN (62)
- FH (60)
- FGFR1 (53)
- G PROTEIN ALPHA S (47)
- BETA CATENIN (46)
- B RAF (43)
- PTEN (43)
- EGFR (39)
- XPD (37)
- FLT4 (33)
- TELOMERASE REVERSE TRANSCRIPTASE (30)
- CBL (24)
- P16INK4A (24)
- P21 RAS (24)
- KRAS (21)
- PKC GAMMA (21)
- RAF1 (18)
- NRAS (17)
- ROR2 (16)
- ALK (13)
- MEK2 (12)
- GLYPICAN 3 (11)
- N-MYC (11)
- BUBR1 (10)
- GRK1 (10)
- MEK1 (10)
- P57 KIP2 (10)
- ACTIVIN RECEPTOR TYPE IA (9)
- AMHR2 (9)
- MET (9)
- E CADHERIN (8)
- P2RY5 (7)
- GATA1 (6)
- MERTK (6)
- AXIN 1 (5)
- CBLB (5)
- ISOCITRATE DEHYDROGENASE (5)
- RB (5)
- ZAP70 (5)
- CDK4 (4)
- EPOXIDE HYDROLASE (4)
- P27 KIP 1 (4)
- PAK3 (4)
- STAT1 (4)
- TPOR (4)
- TYK2 (4)
- XRCC1 (4)
- AURORA A (3)
- AXIN 2 (3)
- C MAF (3)
- DDR2 (3)
- GRK4 (3)
- HEPARIN COFACTOR II (3)
- IDH2 (3)
- AKT1 (2)
- B MYB (2)
- C-MYC (2)
- HIF-1 ALPHA (2)
- TIE2 (2)
- AURORA C (1)
- BCL2 (1)
- CDK7 (1)
- EPH RECEPTOR A2 (1)
- FGFR4 (1)
- FLT3 (1)
- FRK (1)
- GRK5 (1)
- HER2 (1)
- HOXB13 (1)
- INTEGRIN LINKED KINASE (1)
- IRAK (1)
- JAGGED 2 (1)
- LTK (1)
- LYN (1)
- MASTL (1)
- MCSF RECEPTOR (1)
- MYO3A (1)
- PASK (1)
- PIK3C2G (1)
- PKC ETA (1)
- PKN BETA (1)
- RASSF1 (1)
- RON (1)
- RYK (1)
- TNNI3K (1)
Tags
Mutants
Families
- Druggable Genome (3801)
- Transcription Factors (954)
- Protein Kinase (914)
- Stem cell - Pluripotency (441)
- Transmembrane (386)
- ES Cell Differentiation/IPS (123)
- Secreted Protein (86)
- Adult stem cells (45)
- Phosphatase (43)
- Stem cell relevant signaling - JAK/STAT signaling pathway (41)
- Cancer stem cells (39)
- GPCR (7)
- Stem cell relevant signaling - Wnt Signaling pathway (7)
- Induced pluripotent stem cells (5)
- Protease (4)
- Embryonic stem cells (2)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (2)
Pathways
- Pathways in cancer (1682)
- Colorectal cancer (916)
- Insulin signaling pathway (732)
- Endometrial cancer (717)
- Pancreatic cancer (633)
- Mismatch repair (528)
- Prostate cancer (528)
- Melanoma (521)
- Thyroid cancer (484)
- Glioma (472)
- B cell receptor signaling pathway (463)
- Fc epsilon RI signaling pathway (463)
- mTOR signaling pathway (436)
- p53 signaling pathway (433)
- Non-small cell lung cancer (431)
- Ubiquitin mediated proteolysis (417)
- Chronic myeloid leukemia (404)
- MAPK signaling pathway (385)
- Focal adhesion (362)
- Bladder cancer (351)
- Neurotrophin signaling pathway (338)
- Metabolic pathways (318)
- Type II diabetes mellitus (316)
- ErbB signaling pathway (314)
- Regulation of actin cytoskeleton (309)
- Endocytosis (296)
- Primary immunodeficiency (296)
- Renal cell carcinoma (289)
- Homologous recombination (273)
- Small cell lung cancer (250)
- Amino sugar and nucleotide sugar metabolism (249)
- Galactose metabolism (249)
- Glycolysis / Gluconeogenesis (249)
- Maturity onset diabetes of the young (249)
- Starch and sucrose metabolism (249)
- Natural killer cell mediated cytotoxicity (238)
- Dorso-ventral axis formation (226)
- Chemokine signaling pathway (221)
- Acute myeloid leukemia (217)
- Melanogenesis (216)
- Long-term depression (214)
- T cell receptor signaling pathway (213)
- Gap junction (209)
- Wnt signaling pathway (199)
- Apoptosis (193)
- VEGF signaling pathway (192)
- GnRH signaling pathway (188)
- Cell cycle (182)
- Tight junction (179)
- Basal cell carcinoma (176)
- Long-term potentiation (166)
- Progesterone-mediated oocyte maturation (161)
- Notch signaling pathway (157)
- Adherens junction (156)
- Vascular smooth muscle contraction (152)
- Leukocyte transendothelial migration (134)
- Phosphatidylinositol signaling system (132)
- Amyotrophic lateral sclerosis (ALS) (123)
- Huntington's disease (122)
- Fc gamma R-mediated phagocytosis (119)
- Jak-STAT signaling pathway (112)
- Inositol phosphate metabolism (111)
- Calcium signaling pathway (108)
- Cytokine-cytokine receptor interaction (105)
- Toll-like receptor signaling pathway (96)
- Adipocytokine signaling pathway (84)
- Axon guidance (76)
- Citrate cycle (TCA cycle) (68)
- Vibrio cholerae infection (68)
- Pathogenic Escherichia coli infection (54)
- Epithelial cell signaling in Helicobacter pylori infection (49)
- Dilated cardiomyopathy (47)
- Taste transduction (47)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (46)
- Nucleotide excision repair (38)
- Prion diseases (22)
- TGF-beta signaling pathway (20)
- Oocyte meiosis (13)
- Cell adhesion molecules (CAMs) (8)
- Glutathione metabolism (8)
- Neuroactive ligand-receptor interaction (7)
- Base excision repair (4)
- Metabolism of xenobiotics by cytochrome P450 (4)
- Complement and coagulation cascades (3)
- Hematopoietic cell lineage (2)
- PPAR signaling pathway (1)
