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Species
Target Symbol
- BRCA1 (416)
- BTK (303)
- BRCA2 (284)
- MENIN (265)
- MLH1 (261)
- GLUCOKINASE (260)
- TUBERIN (252)
- MSH2 (224)
- RET (196)
- NOTCH3 (164)
- P53 (143)
- CREM (133)
- NF2 (133)
- CACNA1G (112)
- FGFR1 (102)
- NRG1 (102)
- VEGFA (102)
- MSH6 (97)
- DISC1 (96)
- CACNA1C (95)
- BDNF (92)
- LKB1 (87)
- WILMS TUMOR PROTEIN (82)
- UTY (81)
- ST3GAL3 (77)
- G PROTEIN ALPHA S (75)
- KCNMA1 (75)
- PDE9A (75)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (71)
- TPM1 (70)
- EGFR (66)
- FH (66)
- MORTALITY FACTOR 4 LIKE 2 (65)
- HMGA1 (61)
- IKAROS (61)
- EMA (60)
- PLAGL1 (60)
- NDRG2 (59)
- CTNND1 (58)
- TNNT3 (58)
- ANKS1B (57)
- BETA CATENIN (57)
- SYTL2 (56)
- ARPP21 (55)
- RUNX1T1 (55)
- DYSFERLIN (54)
- DYSTROPHIN (54)
- CONSTITUTIVE ANDROSTANE RECEPTOR (53)
- KCNJ15 (53)
- SYNTABULIN (53)
- UBE2V1 (53)
- MU OPIOID RECEPTOR (51)
- PTEN (51)
- TPD52L2 (51)
- ABLIM2 (50)
- FHL1 (50)
- MEIS2 (50)
- BIM (49)
- BORIS (49)
- CD46 (49)
- FLT4 (49)
- MBD1 (49)
- ATP2C1 (48)
- ESTROGEN RELATED RECEPTOR GAMMA (48)
- IKZF3 (48)
- MYADM (48)
- PRKACB (48)
- SMOX (48)
- B RAF (47)
- BIN1 (47)
- EEF1D (47)
- FGF1 (47)
- GLUCOCORTICOID RECEPTOR (46)
- TCF7L2 (46)
- ALPHA 1 ANTITRYPSIN (45)
- CD44 (45)
- DYNC1I2 (45)
- DYSTROBREVIN ALPHA (45)
- GPM6B (45)
- HFE (45)
- RGS3 (45)
- SGK1 (45)
- TTC23 (45)
- UBE2D3 (45)
- XPD (45)
- APC11 (44)
- MRPL55 (44)
- PRKCBP1 (44)
- SPHK1 (44)
- TNIK (44)
- TNIP1 (44)
- TRPM3 (44)
- FGFR2 (43)
- NAT1 (43)
- P73 (43)
- PAQR6 (43)
- PGAP2 (43)
- PPP2R2B (43)
- TCF4 (43)
- TMEM176B (43)
Tags
Vectors
- pCMV6-Entry (130920)
- pCMV6-AC-GFP (57583)
- pCMV6-XL5 (11485)
- PCMV6-Kan/Neo (6161)
- pCMV6-XL4 (5162)
- pCMV6-AC (3792)
- pCMV6-XL6 (791)
- PCMV6-Neo (248)
- pCMV6-AC-Myc-DDK (152)
- pCMV6-XL5-DDK-His (76)
- pCMV6-Entry2 (19)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (13)
- pCMV6-AC-RFP (11)
- pCMV6-AC-mRFP (11)
- pCMV6-AC-mBFP (10)
- pCMV6-AC-mGFP (10)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (48634)
- Transmembrane (28876)
- Transcription Factors (13621)
- Secreted Protein (7175)
- Protein Kinase (4789)
- Protease (2704)
- Stem cell - Pluripotency (2475)
- ES Cell Differentiation/IPS (2391)
- GPCR (1750)
- Phosphatase (1207)
- Ion Channels: Other (841)
- Nuclear Hormone Receptor (586)
- Adult stem cells (564)
- Ion Channels: Potassium (464)
- Embryonic stem cells (452)
- Cancer stem cells (285)
- Ion Channels: Cys-loop Receptors (278)
- Induced pluripotent stem cells (244)
- P450 (244)
- Ion Channels: Calcium (213)
- Ion Channels: Transient receptor potential (178)
- Stem cell relevant signaling - JAK/STAT signaling pathway (175)
- Ion Channels: Glutamate Receptors (128)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (127)
- Stem cell relevant signaling - DSL/Notch pathway (108)
- Stem cell relevant signaling - Wnt Signaling pathway (103)
- Ion Channels: Sodium (93)
- Ion Channels: ATP Receptors (66)
- Ion Channels: Cyclic nucleotide gated (38)
- Secreted (2)
Pathways
- Metabolic pathways (6930)
- Pathways in cancer (4187)
- MAPK signaling pathway (2599)
- Regulation of actin cytoskeleton (1824)
- Focal adhesion (1772)
- Neuroactive ligand-receptor interaction (1721)
- Cytokine-cytokine receptor interaction (1718)
- Insulin signaling pathway (1663)
- Endocytosis (1561)
- Colorectal cancer (1526)
- Calcium signaling pathway (1490)
- Ubiquitin mediated proteolysis (1461)
- Chemokine signaling pathway (1438)
- Neurotrophin signaling pathway (1370)
- Olfactory transduction (1335)
- Wnt signaling pathway (1261)
- Prostate cancer (1240)
- Pancreatic cancer (1210)
- Huntington's disease (1193)
- Endometrial cancer (1161)
- Tight junction (1145)
- Natural killer cell mediated cytotoxicity (1132)
- Alzheimer's disease (1108)
- Progesterone-mediated oocyte maturation (1092)
- Purine metabolism (1089)
- Jak-STAT signaling pathway (1078)
- Melanoma (1073)
- ErbB signaling pathway (1062)
- Axon guidance (1046)
- Cell cycle (1036)
- B cell receptor signaling pathway (1021)
- p53 signaling pathway (1018)
- T cell receptor signaling pathway (1001)
- Leukocyte transendothelial migration (995)
- Vascular smooth muscle contraction (972)
- Glioma (946)
- Fc epsilon RI signaling pathway (944)
- GnRH signaling pathway (937)
- Chronic myeloid leukemia (919)
- Apoptosis (918)
- Melanogenesis (907)
- Oocyte meiosis (888)
- mTOR signaling pathway (875)
- Adherens junction (874)
- Small cell lung cancer (859)
- Cell adhesion molecules (CAMs) (856)
- Renal cell carcinoma (841)
- Non-small cell lung cancer (838)
- Gap junction (819)
- Type II diabetes mellitus (816)
- Fc gamma R-mediated phagocytosis (806)
- VEGF signaling pathway (805)
- Dilated cardiomyopathy (802)
- Lysosome (793)
- Toll-like receptor signaling pathway (762)
- Thyroid cancer (749)
- Long-term potentiation (742)
- Acute myeloid leukemia (730)
- Long-term depression (719)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (709)
- Bladder cancer (707)
- Mismatch repair (702)
- Hypertrophic cardiomyopathy (HCM) (684)
- Glycolysis / Gluconeogenesis (679)
- Spliceosome (659)
- Hematopoietic cell lineage (646)
- Pyrimidine metabolism (641)
- Parkinson's disease (635)
- Oxidative phosphorylation (614)
- Systemic lupus erythematosus (608)
- Phosphatidylinositol signaling system (587)
- Adipocytokine signaling pathway (582)
- Viral myocarditis (570)
- Amino sugar and nucleotide sugar metabolism (561)
- Primary immunodeficiency (538)
- Amyotrophic lateral sclerosis (ALS) (537)
- Starch and sucrose metabolism (533)
- PPAR signaling pathway (519)
- TGF-beta signaling pathway (518)
- ECM-receptor interaction (510)
- Antigen processing and presentation (502)
- Cardiac muscle contraction (492)
- NOD-like receptor signaling pathway (484)
- Basal cell carcinoma (483)
- Epithelial cell signaling in Helicobacter pylori infection (482)
- Homologous recombination (461)
- Glycerophospholipid metabolism (450)
- Complement and coagulation cascades (442)
- Ribosome (441)
- Inositol phosphate metabolism (440)
- RIG-I-like receptor signaling pathway (433)
- Vibrio cholerae infection (431)
- Notch signaling pathway (422)
- Galactose metabolism (416)
- Pathogenic Escherichia coli infection (411)
- Maturity onset diabetes of the young (406)
- Drug metabolism - cytochrome P450 (399)
- Metabolism of xenobiotics by cytochrome P450 (392)
- Dorso-ventral axis formation (382)
- Cytosolic DNA-sensing pathway (354)
- Arginine and proline metabolism (350)
- Taste transduction (348)
- RNA degradation (342)
- Arachidonic acid metabolism (334)
- Glutathione metabolism (325)
- Hedgehog signaling pathway (321)
- Retinol metabolism (321)
- Drug metabolism - other enzymes (319)
- Valine (314)
- Nucleotide excision repair (307)
- Tyrosine metabolism (294)
- Pyruvate metabolism (287)
- Glycerolipid metabolism (281)
- N-Glycan biosynthesis (281)
- Fatty acid metabolism (277)
- Autoimmune thyroid disease (273)
- Lysine degradation (270)
- Proteasome (264)
- leucine and isoleucine degradation (264)
- Citrate cycle (TCA cycle) (262)
- ABC transporters (258)
- Prion diseases (258)
- Sphingolipid metabolism (258)
- Base excision repair (256)
- Type I diabetes mellitus (256)
- Cysteine and methionine metabolism (242)
- Tryptophan metabolism (237)
- Graft-versus-host disease (225)
- Porphyrin and chlorophyll metabolism (213)
- Fructose and mannose metabolism (212)
- Propanoate metabolism (211)
- DNA replication (210)
- Glycosphingolipid biosynthesis - lacto and neolacto series (208)
- Aminoacyl-tRNA biosynthesis (206)
- Alanine (202)
- SNARE interactions in vesicular transport (202)
- aspartate and glutamate metabolism (202)
- Androgen and estrogen metabolism (201)
- Allograft rejection (200)
- Ether lipid metabolism (192)
- Basal transcription factors (188)
- Histidine metabolism (182)
- Selenoamino acid metabolism (179)
- Glycine (177)
- serine and threonine metabolism (177)
- Butanoate metabolism (176)
- Pentose phosphate pathway (175)
- Nitrogen metabolism (167)
- Regulation of autophagy (163)
- RNA polymerase (157)
- Phenylalanine metabolism (155)
- Glycosaminoglycan degradation (154)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (145)
- Linoleic acid metabolism (142)
- O-Glycan biosynthesis (140)
- Pentose and glucuronate interconversions (136)
- Asthma (135)
- Nicotinate and nicotinamide metabolism (135)
- Keratan sulfate biosynthesis (130)
- One carbon pool by folate (123)
- beta-Alanine metabolism (123)
- Ascorbate and aldarate metabolism (121)
- Pantothenate and CoA biosynthesis (120)
- Biosynthesis of unsaturated fatty acids (117)
- Heparan sulfate biosynthesis (114)
- Steroid biosynthesis (107)
- Chondroitin sulfate biosynthesis (106)
- Riboflavin metabolism (106)
- Other glycan degradation (104)
- Primary bile acid biosynthesis (98)
- Sulfur metabolism (97)
- alpha-Linolenic acid metabolism (93)
- Renin-angiotensin system (92)
- Non-homologous end-joining (91)
- Glyoxylate and dicarboxylate metabolism (90)
- Terpenoid backbone biosynthesis (90)
- Glycosphingolipid biosynthesis - ganglio series (88)
- Glycosphingolipid biosynthesis - globo series (88)
- Limonene and pinene degradation (86)
- Circadian rhythm - mammal (79)
- Taurine and hypotaurine metabolism (78)
- Protein export (77)
- Cyanoamino acid metabolism (76)
- leucine and isoleucine biosynthesis (74)
- C21-Steroid hormone metabolism (57)
- Thiamine metabolism (56)
- Folate biosynthesis (54)
- Caffeine metabolism (50)
- Fatty acid elongation in mitochondria (45)
- Synthesis and degradation of ketone bodies (45)
- Fatty acid biosynthesis (41)
- Methane metabolism (37)
- Ubiquinone and other terpenoid-quinone biosynthesis (34)
- Lipoic acid metabolism (32)
- Lysine biosynthesis (30)
- Phenylalanine (29)
- tyrosine and tryptophan biosynthesis (29)
- D-Glutamine and D-glutamate metabolism (22)
- O-Mannosyl glycan biosynthesis (21)
- Vitamin B6 metabolism (21)
- Biotin metabolism (20)
- D-Arginine and D-ornithine metabolism (4)
