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Species
Target Symbol
- BRCA1 (416)
- BTK (303)
- BRCA2 (284)
- MENIN (265)
- MLH1 (261)
- GLUCOKINASE (260)
- TUBERIN (252)
- MSH2 (224)
- RET (196)
- NOTCH3 (164)
- P53 (138)
- NF2 (133)
- CREM (127)
- CACNA1G (112)
- FGFR1 (102)
- VEGFA (100)
- MSH6 (97)
- NRG1 (93)
- BDNF (92)
- LKB1 (87)
- WILMS TUMOR PROTEIN (82)
- DISC1 (81)
- UTY (81)
- ST3GAL3 (77)
- G PROTEIN ALPHA S (75)
- PDE9A (75)
- KCNMA1 (72)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (71)
- EGFR (66)
- FH (66)
- MORTALITY FACTOR 4 LIKE 2 (65)
- IKAROS (61)
- EMA (60)
- PLAGL1 (60)
- CACNA1C (59)
- NDRG2 (59)
- CTNND1 (58)
- ANKS1B (57)
- BETA CATENIN (57)
- ARPP21 (55)
- RUNX1T1 (55)
- DYSTROPHIN (54)
- CONSTITUTIVE ANDROSTANE RECEPTOR (53)
- KCNJ15 (53)
- SYNTABULIN (53)
- MU OPIOID RECEPTOR (51)
- PTEN (51)
- TPD52L2 (51)
- UBE2V1 (51)
- ABLIM2 (50)
- SYTL2 (50)
- TNNT3 (50)
- BIM (49)
- BORIS (49)
- CD46 (49)
- FLT4 (49)
- MBD1 (49)
- ATP2C1 (48)
- ESTROGEN RELATED RECEPTOR GAMMA (48)
- IKZF3 (48)
- MYADM (48)
- SMOX (48)
- B RAF (47)
- BIN1 (47)
- EEF1D (47)
- FGF1 (47)
- FHL1 (47)
- GLUCOCORTICOID RECEPTOR (46)
- TCF7L2 (46)
- TPM1 (46)
- ALPHA 1 ANTITRYPSIN (45)
- CD44 (45)
- DYNC1I2 (45)
- GPM6B (45)
- HFE (45)
- RGS3 (45)
- TTC23 (45)
- UBE2D3 (45)
- XPD (45)
- APC11 (44)
- MEIS2 (44)
- MRPL55 (44)
- PRKCBP1 (44)
- SPHK1 (44)
- TNIP1 (44)
- TRPM3 (44)
- HMGA1 (43)
- NAT1 (43)
- P73 (43)
- PAQR6 (43)
- PGAP2 (43)
- PPP2R2B (43)
- TCF4 (43)
- TMEM176B (43)
- ADAM15 (42)
- CD36 (42)
- DNMT3B (42)
- DYSTROBREVIN ALPHA (42)
- IFI27 (42)
- MIER1 (42)
Tags
Vectors
- pCMV6-Entry (127573)
- pCMV6-AC-GFP (56466)
- pCMV6-XL5 (11180)
- PCMV6-Kan/Neo (6161)
- pCMV6-XL4 (5162)
- pCMV6-AC (3792)
- pCMV6-XL6 (791)
- PCMV6-Neo (248)
- pCMV6-AC-Myc-DDK (152)
- pCMV6-XL5-DDK-His (76)
- pCMV6-Entry2 (19)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (13)
- pCMV6-AC-RFP (11)
- pCMV6-AC-mRFP (11)
- pCMV6-AC-mBFP (10)
- pCMV6-AC-mGFP (10)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (48123)
- Transmembrane (28591)
- Transcription Factors (13395)
- Secreted Protein (7124)
- Protein Kinase (4747)
- Protease (2685)
- Stem cell - Pluripotency (2448)
- ES Cell Differentiation/IPS (2376)
- GPCR (1747)
- Phosphatase (1195)
- Ion Channels: Other (835)
- Nuclear Hormone Receptor (578)
- Adult stem cells (561)
- Ion Channels: Potassium (452)
- Embryonic stem cells (449)
- Cancer stem cells (285)
- Ion Channels: Cys-loop Receptors (278)
- Induced pluripotent stem cells (244)
- P450 (241)
- Ion Channels: Transient receptor potential (178)
- Ion Channels: Calcium (177)
- Stem cell relevant signaling - JAK/STAT signaling pathway (175)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (127)
- Ion Channels: Glutamate Receptors (125)
- Stem cell relevant signaling - DSL/Notch pathway (108)
- Stem cell relevant signaling - Wnt Signaling pathway (103)
- Ion Channels: Sodium (87)
- Ion Channels: ATP Receptors (66)
- Ion Channels: Cyclic nucleotide gated (38)
- Secreted (2)
Pathways
- Metabolic pathways (6873)
- Pathways in cancer (4160)
- MAPK signaling pathway (2539)
- Regulation of actin cytoskeleton (1800)
- Focal adhesion (1754)
- Neuroactive ligand-receptor interaction (1716)
- Cytokine-cytokine receptor interaction (1715)
- Insulin signaling pathway (1654)
- Endocytosis (1558)
- Colorectal cancer (1517)
- Ubiquitin mediated proteolysis (1458)
- Calcium signaling pathway (1448)
- Chemokine signaling pathway (1438)
- Neurotrophin signaling pathway (1364)
- Olfactory transduction (1335)
- Wnt signaling pathway (1249)
- Prostate cancer (1234)
- Pancreatic cancer (1204)
- Huntington's disease (1178)
- Endometrial cancer (1152)
- Tight junction (1133)
- Natural killer cell mediated cytotoxicity (1132)
- Progesterone-mediated oocyte maturation (1089)
- Purine metabolism (1077)
- Jak-STAT signaling pathway (1075)
- Alzheimer's disease (1069)
- Melanoma (1067)
- ErbB signaling pathway (1047)
- Axon guidance (1043)
- Cell cycle (1024)
- B cell receptor signaling pathway (1021)
- p53 signaling pathway (1006)
- T cell receptor signaling pathway (995)
- Leukocyte transendothelial migration (989)
- Fc epsilon RI signaling pathway (944)
- Glioma (940)
- Vascular smooth muscle contraction (936)
- Chronic myeloid leukemia (907)
- Apoptosis (906)
- GnRH signaling pathway (904)
- Melanogenesis (904)
- Oocyte meiosis (885)
- mTOR signaling pathway (869)
- Adherens junction (856)
- Cell adhesion molecules (CAMs) (847)
- Small cell lung cancer (847)
- Renal cell carcinoma (838)
- Non-small cell lung cancer (832)
- Gap junction (819)
- VEGF signaling pathway (802)
- Lysosome (793)
- Fc gamma R-mediated phagocytosis (791)
- Type II diabetes mellitus (780)
- Dilated cardiomyopathy (769)
- Toll-like receptor signaling pathway (762)
- Thyroid cancer (743)
- Acute myeloid leukemia (730)
- Long-term depression (716)
- Long-term potentiation (709)
- Bladder cancer (701)
- Mismatch repair (699)
- Glycolysis / Gluconeogenesis (676)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (670)
- Spliceosome (653)
- Hypertrophic cardiomyopathy (HCM) (651)
- Hematopoietic cell lineage (643)
- Parkinson's disease (629)
- Pyrimidine metabolism (629)
- Oxidative phosphorylation (608)
- Systemic lupus erythematosus (602)
- Adipocytokine signaling pathway (582)
- Phosphatidylinositol signaling system (578)
- Viral myocarditis (570)
- Amino sugar and nucleotide sugar metabolism (561)
- Primary immunodeficiency (538)
- Amyotrophic lateral sclerosis (ALS) (528)
- Starch and sucrose metabolism (527)
- PPAR signaling pathway (513)
- ECM-receptor interaction (507)
- TGF-beta signaling pathway (506)
- Antigen processing and presentation (502)
- NOD-like receptor signaling pathway (484)
- Epithelial cell signaling in Helicobacter pylori infection (482)
- Basal cell carcinoma (471)
- Homologous recombination (461)
- Cardiac muscle contraction (456)
- Glycerophospholipid metabolism (450)
- Complement and coagulation cascades (442)
- Ribosome (441)
- RIG-I-like receptor signaling pathway (433)
- Inositol phosphate metabolism (431)
- Vibrio cholerae infection (431)
- Notch signaling pathway (422)
- Galactose metabolism (413)
- Pathogenic Escherichia coli infection (408)
- Maturity onset diabetes of the young (406)
- Drug metabolism - cytochrome P450 (399)
- Metabolism of xenobiotics by cytochrome P450 (392)
- Dorso-ventral axis formation (379)
- Cytosolic DNA-sensing pathway (348)
- Arginine and proline metabolism (347)
- Taste transduction (345)
- RNA degradation (339)
- Arachidonic acid metabolism (328)
- Glutathione metabolism (322)
- Retinol metabolism (321)
- Hedgehog signaling pathway (318)
- Drug metabolism - other enzymes (316)
- Valine (311)
- Nucleotide excision repair (304)
- Tyrosine metabolism (294)
- Pyruvate metabolism (284)
- Glycerolipid metabolism (281)
- N-Glycan biosynthesis (281)
- Fatty acid metabolism (277)
- Autoimmune thyroid disease (273)
- Lysine degradation (270)
- Proteasome (264)
- Citrate cycle (TCA cycle) (262)
- leucine and isoleucine degradation (261)
- ABC transporters (258)
- Prion diseases (258)
- Sphingolipid metabolism (258)
- Base excision repair (256)
- Type I diabetes mellitus (256)
- Cysteine and methionine metabolism (239)
- Tryptophan metabolism (234)
- Graft-versus-host disease (225)
- Porphyrin and chlorophyll metabolism (213)
- Fructose and mannose metabolism (209)
- Glycosphingolipid biosynthesis - lacto and neolacto series (208)
- Propanoate metabolism (208)
- DNA replication (207)
- Aminoacyl-tRNA biosynthesis (206)
- SNARE interactions in vesicular transport (202)
- Androgen and estrogen metabolism (201)
- Allograft rejection (200)
- Alanine (199)
- aspartate and glutamate metabolism (199)
- Ether lipid metabolism (192)
- Basal transcription factors (185)
- Histidine metabolism (179)
- Butanoate metabolism (176)
- Selenoamino acid metabolism (173)
- Pentose phosphate pathway (172)
- Glycine (168)
- serine and threonine metabolism (168)
- Nitrogen metabolism (164)
- Regulation of autophagy (163)
- RNA polymerase (157)
- Phenylalanine metabolism (155)
- Glycosaminoglycan degradation (154)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (145)
- Linoleic acid metabolism (142)
- O-Glycan biosynthesis (140)
- Pentose and glucuronate interconversions (136)
- Asthma (135)
- Nicotinate and nicotinamide metabolism (132)
- Keratan sulfate biosynthesis (130)
- Ascorbate and aldarate metabolism (121)
- beta-Alanine metabolism (120)
- Biosynthesis of unsaturated fatty acids (117)
- Pantothenate and CoA biosynthesis (117)
- Heparan sulfate biosynthesis (114)
- One carbon pool by folate (114)
- Steroid biosynthesis (107)
- Chondroitin sulfate biosynthesis (106)
- Riboflavin metabolism (106)
- Other glycan degradation (104)
- Primary bile acid biosynthesis (98)
- Sulfur metabolism (97)
- alpha-Linolenic acid metabolism (93)
- Non-homologous end-joining (91)
- Glyoxylate and dicarboxylate metabolism (90)
- Terpenoid backbone biosynthesis (90)
- Renin-angiotensin system (89)
- Glycosphingolipid biosynthesis - ganglio series (88)
- Glycosphingolipid biosynthesis - globo series (88)
- Limonene and pinene degradation (86)
- Circadian rhythm - mammal (79)
- Protein export (77)
- Taurine and hypotaurine metabolism (75)
- leucine and isoleucine biosynthesis (74)
- Cyanoamino acid metabolism (61)
- C21-Steroid hormone metabolism (57)
- Thiamine metabolism (56)
- Folate biosynthesis (54)
- Caffeine metabolism (50)
- Fatty acid elongation in mitochondria (45)
- Synthesis and degradation of ketone bodies (45)
- Fatty acid biosynthesis (41)
- Ubiquinone and other terpenoid-quinone biosynthesis (34)
- Lipoic acid metabolism (32)
- Lysine biosynthesis (30)
- Phenylalanine (29)
- tyrosine and tryptophan biosynthesis (29)
- Methane metabolism (28)
- D-Glutamine and D-glutamate metabolism (22)
- O-Mannosyl glycan biosynthesis (21)
- Vitamin B6 metabolism (21)
- Biotin metabolism (20)
- D-Arginine and D-ornithine metabolism (4)
