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Species
Target Symbol
- BRCA1 (416)
- BTK (303)
- BRCA2 (284)
- MENIN (265)
- GLUCOKINASE (260)
- TUBERIN (252)
- MLH1 (243)
- MSH2 (221)
- RET (194)
- NOTCH3 (164)
- P53 (138)
- NF2 (133)
- CACNA1G (106)
- MSH6 (97)
- FGFR1 (96)
- VEGFA (95)
- CREM (87)
- LKB1 (87)
- WILMS TUMOR PROTEIN (82)
- DISC1 (81)
- BDNF (80)
- G PROTEIN ALPHA S (75)
- PDE9A (75)
- KCNMA1 (72)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (71)
- NRG1 (67)
- EGFR (66)
- FH (66)
- MORTALITY FACTOR 4 LIKE 2 (65)
- IKAROS (61)
- PLAGL1 (60)
- CTNND1 (58)
- BETA CATENIN (57)
- DYSTROPHIN (54)
- CONSTITUTIVE ANDROSTANE RECEPTOR (53)
- KCNJ15 (53)
- NDRG2 (53)
- ST3GAL3 (53)
- SYNTABULIN (53)
- RUNX1T1 (52)
- MU OPIOID RECEPTOR (51)
- PTEN (51)
- TPD52L2 (51)
- UBE2V1 (51)
- SYTL2 (50)
- CD46 (49)
- FLT4 (49)
- ESTROGEN RELATED RECEPTOR GAMMA (48)
- IKZF3 (48)
- MYADM (48)
- B RAF (47)
- BIN1 (47)
- FGF1 (47)
- ARPP21 (46)
- TPM1 (46)
- ALPHA 1 ANTITRYPSIN (45)
- RGS3 (45)
- UBE2D3 (45)
- XPD (45)
- ABLIM2 (44)
- APC11 (44)
- MEIS2 (44)
- MRPL55 (44)
- PRKCBP1 (44)
- TRPM3 (44)
- HMGA1 (43)
- NAT1 (43)
- PAQR6 (43)
- PGAP2 (43)
- PPP2R2B (43)
- TCF4 (43)
- ATP2C1 (42)
- CD36 (42)
- CD44 (42)
- DNMT3B (42)
- DYSTROBREVIN ALPHA (42)
- EEF1D (42)
- EMA (42)
- IFI27 (42)
- PRKACB (42)
- ZNF83 (42)
- CACNA1C (41)
- FHL1 (41)
- HFE (41)
- TCF7L2 (41)
- BHLHB9 (40)
- BIM (40)
- CAMK2D (40)
- MBD1 (40)
- MIER1 (40)
- RAD17 (40)
- SSH3BP1 (40)
- ALPHA DYSTROGLYCAN (39)
- ANKS1B (39)
- FGFR2 (39)
- MID1 (39)
- MYBPC1 (39)
- ODF2 (39)
- PPHLN1 (39)
- SH2B1 (39)
Tags
Vectors
- pCMV6-Entry (121040)
- pCMV6-AC-GFP (54708)
- pCMV6-XL5 (10854)
- PCMV6-Kan/Neo (6161)
- pCMV6-XL4 (5162)
- pCMV6-AC (3792)
- pCMV6-XL6 (791)
- PCMV6-Neo (248)
- pCMV6-AC-Myc-DDK (152)
- pCMV6-XL5-DDK-His (76)
- pCMV6-Entry2 (19)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (13)
- pCMV6-AC-RFP (11)
- pCMV6-AC-mRFP (11)
- pCMV6-AC-mBFP (10)
- pCMV6-AC-mGFP (10)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (46476)
- Transmembrane (27528)
- Transcription Factors (12853)
- Secreted Protein (6911)
- Protein Kinase (4629)
- Protease (2591)
- Stem cell - Pluripotency (2404)
- ES Cell Differentiation/IPS (2367)
- GPCR (1726)
- Phosphatase (1178)
- Ion Channels: Other (817)
- Nuclear Hormone Receptor (560)
- Adult stem cells (552)
- Embryonic stem cells (440)
- Ion Channels: Potassium (431)
- Cancer stem cells (282)
- Ion Channels: Cys-loop Receptors (269)
- Induced pluripotent stem cells (238)
- P450 (236)
- Stem cell relevant signaling - JAK/STAT signaling pathway (175)
- Ion Channels: Transient receptor potential (164)
- Ion Channels: Calcium (153)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (127)
- Ion Channels: Glutamate Receptors (123)
- Stem cell relevant signaling - DSL/Notch pathway (105)
- Stem cell relevant signaling - Wnt Signaling pathway (100)
- Ion Channels: Sodium (87)
- Ion Channels: ATP Receptors (58)
- Ion Channels: Cyclic nucleotide gated (38)
- Secreted (2)
Pathways
- Metabolic pathways (6644)
- Pathways in cancer (4100)
- MAPK signaling pathway (2467)
- Regulation of actin cytoskeleton (1719)
- Focal adhesion (1718)
- Cytokine-cytokine receptor interaction (1670)
- Neuroactive ligand-receptor interaction (1647)
- Insulin signaling pathway (1642)
- Endocytosis (1523)
- Colorectal cancer (1493)
- Ubiquitin mediated proteolysis (1422)
- Chemokine signaling pathway (1393)
- Calcium signaling pathway (1379)
- Neurotrophin signaling pathway (1352)
- Olfactory transduction (1327)
- Prostate cancer (1219)
- Wnt signaling pathway (1211)
- Pancreatic cancer (1198)
- Huntington's disease (1138)
- Endometrial cancer (1125)
- Natural killer cell mediated cytotoxicity (1102)
- Tight junction (1061)
- Jak-STAT signaling pathway (1058)
- Melanoma (1058)
- Progesterone-mediated oocyte maturation (1052)
- ErbB signaling pathway (1038)
- Purine metabolism (1037)
- Alzheimer's disease (1007)
- Axon guidance (1003)
- Cell cycle (999)
- B cell receptor signaling pathway (990)
- p53 signaling pathway (983)
- T cell receptor signaling pathway (970)
- Leukocyte transendothelial migration (947)
- Fc epsilon RI signaling pathway (939)
- Glioma (937)
- Chronic myeloid leukemia (907)
- Vascular smooth muscle contraction (907)
- Melanogenesis (898)
- GnRH signaling pathway (881)
- Apoptosis (880)
- mTOR signaling pathway (863)
- Oocyte meiosis (861)
- Small cell lung cancer (839)
- Adherens junction (826)
- Non-small cell lung cancer (826)
- Renal cell carcinoma (825)
- Cell adhesion molecules (CAMs) (821)
- Gap junction (799)
- VEGF signaling pathway (775)
- Fc gamma R-mediated phagocytosis (772)
- Lysosome (763)
- Type II diabetes mellitus (756)
- Toll-like receptor signaling pathway (752)
- Dilated cardiomyopathy (751)
- Thyroid cancer (740)
- Acute myeloid leukemia (721)
- Long-term depression (702)
- Bladder cancer (695)
- Long-term potentiation (686)
- Mismatch repair (675)
- Glycolysis / Gluconeogenesis (670)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (646)
- Hypertrophic cardiomyopathy (HCM) (633)
- Hematopoietic cell lineage (627)
- Spliceosome (621)
- Parkinson's disease (611)
- Pyrimidine metabolism (602)
- Systemic lupus erythematosus (599)
- Oxidative phosphorylation (585)
- Adipocytokine signaling pathway (573)
- Viral myocarditis (565)
- Phosphatidylinositol signaling system (559)
- Primary immunodeficiency (529)
- Amino sugar and nucleotide sugar metabolism (526)
- Starch and sucrose metabolism (524)
- Amyotrophic lateral sclerosis (ALS) (523)
- ECM-receptor interaction (507)
- TGF-beta signaling pathway (503)
- Antigen processing and presentation (499)
- PPAR signaling pathway (498)
- NOD-like receptor signaling pathway (481)
- Epithelial cell signaling in Helicobacter pylori infection (469)
- Basal cell carcinoma (468)
- Homologous recombination (455)
- Complement and coagulation cascades (436)
- Cardiac muscle contraction (432)
- Glycerophospholipid metabolism (430)
- RIG-I-like receptor signaling pathway (429)
- Inositol phosphate metabolism (421)
- Ribosome (420)
- Notch signaling pathway (419)
- Vibrio cholerae infection (414)
- Galactose metabolism (407)
- Maturity onset diabetes of the young (406)
- Pathogenic Escherichia coli infection (400)
- Drug metabolism - cytochrome P450 (381)
- Metabolism of xenobiotics by cytochrome P450 (377)
- Dorso-ventral axis formation (376)
- Cytosolic DNA-sensing pathway (341)
- Arginine and proline metabolism (335)
- Taste transduction (333)
- RNA degradation (328)
- Retinol metabolism (315)
- Arachidonic acid metabolism (313)
- Hedgehog signaling pathway (309)
- Glutathione metabolism (306)
- Valine (305)
- Drug metabolism - other enzymes (301)
- Nucleotide excision repair (295)
- Tyrosine metabolism (288)
- Pyruvate metabolism (281)
- N-Glycan biosynthesis (275)
- Autoimmune thyroid disease (273)
- Glycerolipid metabolism (269)
- Fatty acid metabolism (262)
- Lysine degradation (262)
- Citrate cycle (TCA cycle) (260)
- ABC transporters (258)
- Prion diseases (258)
- leucine and isoleucine degradation (258)
- Base excision repair (256)
- Type I diabetes mellitus (253)
- Proteasome (248)
- Sphingolipid metabolism (243)
- Cysteine and methionine metabolism (239)
- Graft-versus-host disease (225)
- Tryptophan metabolism (225)
- Porphyrin and chlorophyll metabolism (213)
- Fructose and mannose metabolism (207)
- Propanoate metabolism (205)
- Androgen and estrogen metabolism (201)
- DNA replication (201)
- Allograft rejection (200)
- Aminoacyl-tRNA biosynthesis (200)
- SNARE interactions in vesicular transport (197)
- Alanine (196)
- aspartate and glutamate metabolism (196)
- Ether lipid metabolism (184)
- Basal transcription factors (182)
- Glycosphingolipid biosynthesis - lacto and neolacto series (174)
- Butanoate metabolism (173)
- Selenoamino acid metabolism (173)
- Histidine metabolism (167)
- Pentose phosphate pathway (166)
- Glycine (165)
- serine and threonine metabolism (165)
- Regulation of autophagy (163)
- RNA polymerase (157)
- Phenylalanine metabolism (149)
- Glycosaminoglycan degradation (148)
- Nitrogen metabolism (146)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (142)
- O-Glycan biosynthesis (140)
- Linoleic acid metabolism (138)
- Pentose and glucuronate interconversions (136)
- Asthma (135)
- Nicotinate and nicotinamide metabolism (132)
- Ascorbate and aldarate metabolism (118)
- Biosynthesis of unsaturated fatty acids (117)
- Pantothenate and CoA biosynthesis (117)
- beta-Alanine metabolism (117)
- One carbon pool by folate (108)
- Steroid biosynthesis (107)
- Keratan sulfate biosynthesis (106)
- Riboflavin metabolism (106)
- Heparan sulfate biosynthesis (104)
- Chondroitin sulfate biosynthesis (101)
- Sulfur metabolism (97)
- Other glycan degradation (95)
- Primary bile acid biosynthesis (95)
- Non-homologous end-joining (91)
- alpha-Linolenic acid metabolism (91)
- Glyoxylate and dicarboxylate metabolism (90)
- Terpenoid backbone biosynthesis (90)
- Renin-angiotensin system (89)
- Glycosphingolipid biosynthesis - ganglio series (88)
- Glycosphingolipid biosynthesis - globo series (88)
- Limonene and pinene degradation (80)
- Circadian rhythm - mammal (79)
- Taurine and hypotaurine metabolism (75)
- leucine and isoleucine biosynthesis (71)
- Cyanoamino acid metabolism (61)
- C21-Steroid hormone metabolism (57)
- Protein export (57)
- Thiamine metabolism (56)
- Folate biosynthesis (54)
- Caffeine metabolism (50)
- Synthesis and degradation of ketone bodies (45)
- Fatty acid elongation in mitochondria (42)
- Fatty acid biosynthesis (41)
- Ubiquinone and other terpenoid-quinone biosynthesis (34)
- Lipoic acid metabolism (32)
- Lysine biosynthesis (30)
- Phenylalanine (29)
- tyrosine and tryptophan biosynthesis (29)
- Methane metabolism (28)
- D-Glutamine and D-glutamate metabolism (22)
- O-Mannosyl glycan biosynthesis (21)
- Vitamin B6 metabolism (21)
- Biotin metabolism (20)
- D-Arginine and D-ornithine metabolism (4)
