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Species
Target Symbol
- BRCA1 (416)
- BTK (303)
- BRCA2 (284)
- MENIN (265)
- GLUCOKINASE (260)
- TUBERIN (252)
- MLH1 (243)
- MSH2 (221)
- RET (194)
- NOTCH3 (164)
- NF2 (127)
- P53 (125)
- FGFR1 (96)
- VEGFA (92)
- MSH6 (91)
- LKB1 (87)
- WILMS TUMOR PROTEIN (82)
- CREM (81)
- DISC1 (81)
- G PROTEIN ALPHA S (75)
- PDE9A (75)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (71)
- CACNA1G (68)
- NRG1 (67)
- BDNF (66)
- EGFR (66)
- FH (66)
- MORTALITY FACTOR 4 LIKE 2 (65)
- PLAGL1 (60)
- BETA CATENIN (57)
- DYSTROPHIN (54)
- CONSTITUTIVE ANDROSTANE RECEPTOR (53)
- SYNTABULIN (53)
- PTEN (51)
- ST3GAL3 (51)
- SYTL2 (50)
- CD46 (49)
- FLT4 (49)
- RUNX1T1 (49)
- MYADM (48)
- B RAF (47)
- BIN1 (47)
- MU OPIOID RECEPTOR (47)
- TPM1 (46)
- ALPHA 1 ANTITRYPSIN (45)
- KCNJ15 (45)
- NDRG2 (45)
- TPD52L2 (45)
- UBE2D3 (45)
- XPD (45)
- APC11 (44)
- MEIS2 (44)
- MRPL55 (44)
- TRPM3 (44)
- ARPP21 (43)
- HMGA1 (43)
- NAT1 (43)
- CD36 (42)
- CD44 (42)
- IFI27 (42)
- FHL1 (41)
- HFE (41)
- BHLHB9 (40)
- CAMK2D (40)
- DYSTROBREVIN ALPHA (40)
- SSH3BP1 (40)
- ALPHA DYSTROGLYCAN (39)
- FGFR2 (39)
- MID1 (39)
- SH2B1 (39)
- SPHK1 (39)
- ABLIM2 (38)
- CAMKK2 (38)
- ENSA (38)
- FGF1 (38)
- GPR56 (38)
- P311 (38)
- PDE4DIP (38)
- RAD17 (38)
- SLITRK2 (38)
- CAMK2B (37)
- CD89 (37)
- OGG1 (37)
- P21 RAS (37)
- PAX3 (37)
- PPP2R2B (37)
- PTGER3 (37)
- TELOMERASE REVERSE TRANSCRIPTASE (37)
- CHRM2 (36)
- EIF5A (36)
- ESTROGEN RELATED RECEPTOR GAMMA (36)
- OSBPL9 (36)
- P16INK4A (36)
- SHUGOSHIN (36)
- TGIF (36)
- TTC23 (36)
- COLLAGEN VI (35)
- MITF (35)
- NEK6 (35)
- PML PROTEIN (35)
Tags
Vectors
- pCMV6-Entry (110347)
- pCMV6-AC-GFP (52735)
- pCMV6-XL5 (10811)
- PCMV6-Kan/Neo (6161)
- pCMV6-XL4 (5162)
- pCMV6-AC (3792)
- pCMV6-XL6 (791)
- PCMV6-Neo (246)
- pCMV6-AC-Myc-DDK (152)
- pCMV6-XL5-DDK-His (76)
- pCMV6-Entry2 (19)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (13)
- pCMV6-AC-RFP (11)
- pCMV6-AC-mRFP (11)
- pCMV6-AC-mBFP (10)
- pCMV6-AC-mGFP (10)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (42996)
- Transmembrane (25578)
- Transcription Factors (11573)
- Secreted Protein (6534)
- Protein Kinase (4352)
- Protease (2391)
- ES Cell Differentiation/IPS (2242)
- Stem cell - Pluripotency (2221)
- GPCR (1638)
- Phosphatase (1071)
- Ion Channels: Other (775)
- Adult stem cells (541)
- Nuclear Hormone Receptor (482)
- Embryonic stem cells (423)
- Ion Channels: Potassium (414)
- Cancer stem cells (280)
- Ion Channels: Cys-loop Receptors (242)
- Induced pluripotent stem cells (227)
- P450 (222)
- Stem cell relevant signaling - JAK/STAT signaling pathway (169)
- Ion Channels: Transient receptor potential (152)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (125)
- Ion Channels: Calcium (108)
- Ion Channels: Glutamate Receptors (102)
- Stem cell relevant signaling - DSL/Notch pathway (99)
- Stem cell relevant signaling - Wnt Signaling pathway (97)
- Ion Channels: Sodium (87)
- Ion Channels: ATP Receptors (48)
- Ion Channels: Cyclic nucleotide gated (36)
- Secreted (2)
Pathways
- Metabolic pathways (6146)
- Pathways in cancer (3941)
- MAPK signaling pathway (2282)
- Focal adhesion (1607)
- Regulation of actin cytoskeleton (1598)
- Cytokine-cytokine receptor interaction (1575)
- Insulin signaling pathway (1560)
- Neuroactive ligand-receptor interaction (1502)
- Colorectal cancer (1437)
- Endocytosis (1395)
- Ubiquitin mediated proteolysis (1311)
- Olfactory transduction (1287)
- Chemokine signaling pathway (1284)
- Neurotrophin signaling pathway (1272)
- Calcium signaling pathway (1267)
- Prostate cancer (1141)
- Pancreatic cancer (1138)
- Wnt signaling pathway (1135)
- Endometrial cancer (1063)
- Huntington's disease (1027)
- Natural killer cell mediated cytotoxicity (1024)
- Melanoma (1008)
- ErbB signaling pathway (991)
- Jak-STAT signaling pathway (971)
- Tight junction (967)
- Progesterone-mediated oocyte maturation (960)
- Cell cycle (945)
- B cell receptor signaling pathway (941)
- Purine metabolism (935)
- Axon guidance (919)
- T cell receptor signaling pathway (903)
- Fc epsilon RI signaling pathway (902)
- p53 signaling pathway (901)
- Glioma (894)
- Alzheimer's disease (881)
- Chronic myeloid leukemia (862)
- Leukocyte transendothelial migration (848)
- Melanogenesis (844)
- GnRH signaling pathway (839)
- Vascular smooth muscle contraction (823)
- mTOR signaling pathway (809)
- Oocyte meiosis (792)
- Apoptosis (783)
- Cell adhesion molecules (CAMs) (780)
- Non-small cell lung cancer (776)
- Small cell lung cancer (776)
- Renal cell carcinoma (770)
- Adherens junction (752)
- Gap junction (742)
- VEGF signaling pathway (721)
- Toll-like receptor signaling pathway (715)
- Thyroid cancer (707)
- Lysosome (706)
- Dilated cardiomyopathy (704)
- Fc gamma R-mediated phagocytosis (702)
- Type II diabetes mellitus (682)
- Acute myeloid leukemia (668)
- Bladder cancer (664)
- Mismatch repair (655)
- Glycolysis / Gluconeogenesis (650)
- Long-term depression (640)
- Long-term potentiation (617)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (609)
- Hematopoietic cell lineage (604)
- Hypertrophic cardiomyopathy (HCM) (597)
- Systemic lupus erythematosus (582)
- Spliceosome (577)
- Parkinson's disease (549)
- Pyrimidine metabolism (542)
- Adipocytokine signaling pathway (536)
- Oxidative phosphorylation (533)
- Viral myocarditis (530)
- Primary immunodeficiency (521)
- Phosphatidylinositol signaling system (507)
- Starch and sucrose metabolism (505)
- Amino sugar and nucleotide sugar metabolism (491)
- ECM-receptor interaction (481)
- TGF-beta signaling pathway (479)
- Antigen processing and presentation (474)
- Amyotrophic lateral sclerosis (ALS) (469)
- Epithelial cell signaling in Helicobacter pylori infection (454)
- PPAR signaling pathway (452)
- NOD-like receptor signaling pathway (447)
- Basal cell carcinoma (446)
- Homologous recombination (441)
- Complement and coagulation cascades (424)
- Cardiac muscle contraction (409)
- Galactose metabolism (405)
- Maturity onset diabetes of the young (404)
- RIG-I-like receptor signaling pathway (404)
- Ribosome (403)
- Notch signaling pathway (400)
- Pathogenic Escherichia coli infection (398)
- Vibrio cholerae infection (396)
- Inositol phosphate metabolism (386)
- Glycerophospholipid metabolism (384)
- Drug metabolism - cytochrome P450 (357)
- Dorso-ventral axis formation (355)
- Metabolism of xenobiotics by cytochrome P450 (351)
- Cytosolic DNA-sensing pathway (323)
- Arginine and proline metabolism (308)
- Glutathione metabolism (296)
- RNA degradation (296)
- Taste transduction (293)
- Valine (286)
- Hedgehog signaling pathway (282)
- Arachidonic acid metabolism (281)
- Retinol metabolism (277)
- Drug metabolism - other enzymes (274)
- Pyruvate metabolism (264)
- Autoimmune thyroid disease (262)
- Tyrosine metabolism (260)
- N-Glycan biosynthesis (257)
- Lysine degradation (254)
- Nucleotide excision repair (252)
- Glycerolipid metabolism (248)
- Citrate cycle (TCA cycle) (245)
- Fatty acid metabolism (243)
- Type I diabetes mellitus (241)
- leucine and isoleucine degradation (239)
- ABC transporters (238)
- Sphingolipid metabolism (232)
- Prion diseases (228)
- Base excision repair (224)
- Cysteine and methionine metabolism (218)
- Graft-versus-host disease (216)
- Proteasome (211)
- Tryptophan metabolism (207)
- Porphyrin and chlorophyll metabolism (199)
- Allograft rejection (194)
- Androgen and estrogen metabolism (192)
- Propanoate metabolism (189)
- Alanine (187)
- Fructose and mannose metabolism (187)
- aspartate and glutamate metabolism (187)
- DNA replication (181)
- SNARE interactions in vesicular transport (181)
- Aminoacyl-tRNA biosynthesis (174)
- Ether lipid metabolism (172)
- Glycosphingolipid biosynthesis - lacto and neolacto series (171)
- Butanoate metabolism (170)
- Basal transcription factors (161)
- Selenoamino acid metabolism (158)
- Glycine (156)
- serine and threonine metabolism (156)
- Histidine metabolism (149)
- Pentose phosphate pathway (148)
- Regulation of autophagy (147)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (142)
- Glycosaminoglycan degradation (140)
- Nitrogen metabolism (140)
- O-Glycan biosynthesis (137)
- RNA polymerase (132)
- Asthma (130)
- Linoleic acid metabolism (128)
- Nicotinate and nicotinamide metabolism (126)
- Phenylalanine metabolism (124)
- Pentose and glucuronate interconversions (117)
- Pantothenate and CoA biosynthesis (115)
- Ascorbate and aldarate metabolism (106)
- Keratan sulfate biosynthesis (106)
- Heparan sulfate biosynthesis (104)
- beta-Alanine metabolism (104)
- Biosynthesis of unsaturated fatty acids (101)
- Chondroitin sulfate biosynthesis (101)
- Riboflavin metabolism (100)
- Steroid biosynthesis (99)
- One carbon pool by folate (97)
- Sulfur metabolism (91)
- Other glycan degradation (89)
- Renin-angiotensin system (89)
- Primary bile acid biosynthesis (88)
- Non-homologous end-joining (87)
- Glycosphingolipid biosynthesis - globo series (84)
- alpha-Linolenic acid metabolism (84)
- Glycosphingolipid biosynthesis - ganglio series (82)
- Circadian rhythm - mammal (79)
- Terpenoid backbone biosynthesis (78)
- Glyoxylate and dicarboxylate metabolism (77)
- Taurine and hypotaurine metabolism (72)
- leucine and isoleucine biosynthesis (69)
- Limonene and pinene degradation (65)
- C21-Steroid hormone metabolism (57)
- Cyanoamino acid metabolism (57)
- Folate biosynthesis (54)
- Caffeine metabolism (50)
- Synthesis and degradation of ketone bodies (45)
- Thiamine metabolism (44)
- Fatty acid biosynthesis (41)
- Protein export (39)
- Fatty acid elongation in mitochondria (38)
- Ubiquinone and other terpenoid-quinone biosynthesis (34)
- Lysine biosynthesis (30)
- Phenylalanine (29)
- tyrosine and tryptophan biosynthesis (29)
- Lipoic acid metabolism (26)
- Methane metabolism (26)
- Vitamin B6 metabolism (21)
- O-Mannosyl glycan biosynthesis (19)
- D-Glutamine and D-glutamate metabolism (16)
- Biotin metabolism (14)
- D-Arginine and D-ornithine metabolism (4)
