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Species
Target Symbol
- BRCA1 (416)
- BTK (301)
- BRCA2 (284)
- MENIN (265)
- GLUCOKINASE (260)
- TUBERIN (252)
- MLH1 (243)
- MSH2 (221)
- RET (194)
- NOTCH3 (164)
- NF2 (125)
- P53 (125)
- FGFR1 (96)
- MSH6 (91)
- LKB1 (87)
- VEGFA (84)
- WILMS TUMOR PROTEIN (82)
- CREM (81)
- DISC1 (81)
- G PROTEIN ALPHA S (75)
- PDE9A (75)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (71)
- NRG1 (67)
- BDNF (66)
- EGFR (66)
- FH (66)
- MORTALITY FACTOR 4 LIKE 2 (65)
- CACNA1G (62)
- PLAGL1 (60)
- BETA CATENIN (57)
- DYSTROPHIN (54)
- CONSTITUTIVE ANDROSTANE RECEPTOR (53)
- SYNTABULIN (53)
- PTEN (51)
- ST3GAL3 (51)
- CD46 (49)
- FLT4 (49)
- RUNX1T1 (49)
- MYADM (48)
- B RAF (47)
- BIN1 (47)
- MU OPIOID RECEPTOR (47)
- TPM1 (46)
- ALPHA 1 ANTITRYPSIN (45)
- KCNJ15 (45)
- NDRG2 (45)
- UBE2D3 (45)
- XPD (45)
- MEIS2 (44)
- MRPL55 (44)
- SYTL2 (44)
- TRPM3 (44)
- HMGA1 (43)
- NAT1 (43)
- APC11 (42)
- CD44 (42)
- TPD52L2 (42)
- HFE (41)
- ARPP21 (40)
- BHLHB9 (40)
- DYSTROBREVIN ALPHA (40)
- SSH3BP1 (40)
- ALPHA DYSTROGLYCAN (39)
- FGFR2 (39)
- FHL1 (39)
- SPHK1 (39)
- CAMKK2 (38)
- CD36 (38)
- ENSA (38)
- FGF1 (38)
- IFI27 (38)
- P311 (38)
- RAD17 (38)
- SLITRK2 (38)
- CAMK2B (37)
- CD89 (37)
- OGG1 (37)
- P21 RAS (37)
- PAX3 (37)
- PPP2R2B (37)
- PTGER3 (37)
- SH2B1 (37)
- TELOMERASE REVERSE TRANSCRIPTASE (37)
- CHRM2 (36)
- EIF5A (36)
- ESTROGEN RELATED RECEPTOR GAMMA (36)
- GPR56 (36)
- OSBPL9 (36)
- P16INK4A (36)
- SHUGOSHIN (36)
- TGIF (36)
- TTC23 (36)
- COLLAGEN VI (35)
- MID1 (35)
- MITF (35)
- NEK6 (35)
- PML PROTEIN (35)
- PPHLN1 (35)
- RGS3 (35)
- TCF7L2 (35)
Tags
Vectors
- pCMV6-Entry (106358)
- pCMV6-AC-GFP (52495)
- pCMV6-XL5 (10804)
- PCMV6-Kan/Neo (6161)
- pCMV6-XL4 (5162)
- pCMV6-AC (3792)
- pCMV6-XL6 (791)
- PCMV6-Neo (246)
- pCMV6-AC-Myc-DDK (152)
- pCMV6-XL5-DDK-His (76)
- pCMV6-Entry2 (19)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (13)
- pCMV6-AC-RFP (11)
- pCMV6-AC-mRFP (11)
- pCMV6-AC-mBFP (10)
- pCMV6-AC-mGFP (10)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (41906)
- Transmembrane (24947)
- Transcription Factors (11251)
- Secreted Protein (6412)
- Protein Kinase (4256)
- Protease (2338)
- ES Cell Differentiation/IPS (2218)
- Stem cell - Pluripotency (2166)
- GPCR (1624)
- Phosphatase (1041)
- Ion Channels: Other (763)
- Adult stem cells (535)
- Nuclear Hormone Receptor (474)
- Embryonic stem cells (419)
- Ion Channels: Potassium (408)
- Cancer stem cells (276)
- Ion Channels: Cys-loop Receptors (236)
- Induced pluripotent stem cells (227)
- P450 (218)
- Stem cell relevant signaling - JAK/STAT signaling pathway (167)
- Ion Channels: Transient receptor potential (149)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (121)
- Ion Channels: Calcium (102)
- Ion Channels: Glutamate Receptors (102)
- Stem cell relevant signaling - DSL/Notch pathway (97)
- Stem cell relevant signaling - Wnt Signaling pathway (97)
- Ion Channels: Sodium (83)
- Ion Channels: ATP Receptors (48)
- Ion Channels: Cyclic nucleotide gated (33)
- Secreted (2)
Pathways
- Metabolic pathways (5960)
- Pathways in cancer (3892)
- MAPK signaling pathway (2231)
- Focal adhesion (1580)
- Regulation of actin cytoskeleton (1575)
- Cytokine-cytokine receptor interaction (1543)
- Insulin signaling pathway (1540)
- Neuroactive ligand-receptor interaction (1487)
- Colorectal cancer (1420)
- Endocytosis (1366)
- Ubiquitin mediated proteolysis (1291)
- Olfactory transduction (1276)
- Chemokine signaling pathway (1251)
- Neurotrophin signaling pathway (1248)
- Calcium signaling pathway (1246)
- Pancreatic cancer (1125)
- Prostate cancer (1124)
- Wnt signaling pathway (1122)
- Endometrial cancer (1048)
- Natural killer cell mediated cytotoxicity (1005)
- Huntington's disease (1002)
- Melanoma (995)
- ErbB signaling pathway (974)
- Tight junction (952)
- Jak-STAT signaling pathway (947)
- B cell receptor signaling pathway (928)
- Cell cycle (916)
- Progesterone-mediated oocyte maturation (912)
- Axon guidance (902)
- Fc epsilon RI signaling pathway (892)
- Purine metabolism (890)
- T cell receptor signaling pathway (886)
- p53 signaling pathway (883)
- Glioma (881)
- Alzheimer's disease (861)
- Chronic myeloid leukemia (849)
- Melanogenesis (839)
- Leukocyte transendothelial migration (835)
- GnRH signaling pathway (832)
- Vascular smooth muscle contraction (802)
- mTOR signaling pathway (801)
- Cell adhesion molecules (CAMs) (775)
- Oocyte meiosis (766)
- Apoptosis (761)
- Non-small cell lung cancer (759)
- Small cell lung cancer (758)
- Renal cell carcinoma (756)
- Adherens junction (732)
- Gap junction (714)
- VEGF signaling pathway (711)
- Toll-like receptor signaling pathway (703)
- Thyroid cancer (699)
- Dilated cardiomyopathy (696)
- Fc gamma R-mediated phagocytosis (688)
- Lysosome (684)
- Type II diabetes mellitus (673)
- Acute myeloid leukemia (657)
- Bladder cancer (653)
- Mismatch repair (648)
- Glycolysis / Gluconeogenesis (635)
- Long-term depression (620)
- Long-term potentiation (606)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (600)
- Hypertrophic cardiomyopathy (HCM) (592)
- Hematopoietic cell lineage (589)
- Systemic lupus erythematosus (580)
- Spliceosome (571)
- Parkinson's disease (540)
- Viral myocarditis (527)
- Pyrimidine metabolism (523)
- Oxidative phosphorylation (520)
- Primary immunodeficiency (515)
- Adipocytokine signaling pathway (512)
- Phosphatidylinositol signaling system (494)
- Starch and sucrose metabolism (492)
- Amino sugar and nucleotide sugar metabolism (480)
- TGF-beta signaling pathway (479)
- Antigen processing and presentation (470)
- ECM-receptor interaction (467)
- Amyotrophic lateral sclerosis (ALS) (457)
- Epithelial cell signaling in Helicobacter pylori infection (450)
- Basal cell carcinoma (444)
- NOD-like receptor signaling pathway (442)
- Homologous recombination (433)
- PPAR signaling pathway (430)
- Complement and coagulation cascades (424)
- Maturity onset diabetes of the young (404)
- Galactose metabolism (403)
- Ribosome (403)
- Cardiac muscle contraction (402)
- RIG-I-like receptor signaling pathway (398)
- Vibrio cholerae infection (389)
- Notch signaling pathway (385)
- Pathogenic Escherichia coli infection (382)
- Inositol phosphate metabolism (372)
- Glycerophospholipid metabolism (370)
- Dorso-ventral axis formation (350)
- Drug metabolism - cytochrome P450 (329)
- Metabolism of xenobiotics by cytochrome P450 (323)
- Arginine and proline metabolism (302)
- Cytosolic DNA-sensing pathway (301)
- Taste transduction (285)
- RNA degradation (284)
- Valine (280)
- Hedgehog signaling pathway (277)
- Glutathione metabolism (276)
- Arachidonic acid metabolism (273)
- Retinol metabolism (267)
- Autoimmune thyroid disease (262)
- Drug metabolism - other enzymes (260)
- Pyruvate metabolism (256)
- N-Glycan biosynthesis (253)
- Tyrosine metabolism (253)
- Glycerolipid metabolism (246)
- Nucleotide excision repair (245)
- Type I diabetes mellitus (241)
- Lysine degradation (239)
- Fatty acid metabolism (237)
- Citrate cycle (TCA cycle) (235)
- leucine and isoleucine degradation (233)
- Sphingolipid metabolism (232)
- ABC transporters (231)
- Prion diseases (219)
- Graft-versus-host disease (216)
- Base excision repair (211)
- Proteasome (211)
- Cysteine and methionine metabolism (210)
- Tryptophan metabolism (202)
- Allograft rejection (194)
- Propanoate metabolism (189)
- Alanine (187)
- aspartate and glutamate metabolism (187)
- Androgen and estrogen metabolism (186)
- Porphyrin and chlorophyll metabolism (184)
- Fructose and mannose metabolism (180)
- SNARE interactions in vesicular transport (177)
- DNA replication (172)
- Ether lipid metabolism (172)
- Aminoacyl-tRNA biosynthesis (170)
- Butanoate metabolism (170)
- Glycosphingolipid biosynthesis - lacto and neolacto series (168)
- Basal transcription factors (157)
- Selenoamino acid metabolism (156)
- Glycine (152)
- serine and threonine metabolism (152)
- Regulation of autophagy (147)
- Pentose phosphate pathway (146)
- Histidine metabolism (142)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (138)
- Glycosaminoglycan degradation (136)
- Nitrogen metabolism (134)
- O-Glycan biosynthesis (132)
- RNA polymerase (132)
- Asthma (130)
- Linoleic acid metabolism (124)
- Nicotinate and nicotinamide metabolism (124)
- Phenylalanine metabolism (117)
- Pantothenate and CoA biosynthesis (109)
- Keratan sulfate biosynthesis (106)
- Pentose and glucuronate interconversions (106)
- beta-Alanine metabolism (104)
- Heparan sulfate biosynthesis (102)
- Biosynthesis of unsaturated fatty acids (101)
- Chondroitin sulfate biosynthesis (99)
- Riboflavin metabolism (98)
- Ascorbate and aldarate metabolism (97)
- One carbon pool by folate (91)
- Sulfur metabolism (91)
- Renin-angiotensin system (89)
- Steroid biosynthesis (89)
- Non-homologous end-joining (85)
- Primary bile acid biosynthesis (84)
- alpha-Linolenic acid metabolism (84)
- Other glycan degradation (82)
- Glycosphingolipid biosynthesis - globo series (80)
- Terpenoid backbone biosynthesis (78)
- Glyoxylate and dicarboxylate metabolism (77)
- Glycosphingolipid biosynthesis - ganglio series (76)
- Circadian rhythm - mammal (71)
- leucine and isoleucine biosynthesis (69)
- Taurine and hypotaurine metabolism (67)
- Limonene and pinene degradation (65)
- C21-Steroid hormone metabolism (57)
- Cyanoamino acid metabolism (55)
- Folate biosynthesis (52)
- Caffeine metabolism (50)
- Synthesis and degradation of ketone bodies (45)
- Fatty acid biosynthesis (41)
- Protein export (39)
- Thiamine metabolism (39)
- Fatty acid elongation in mitochondria (38)
- Ubiquinone and other terpenoid-quinone biosynthesis (34)
- Phenylalanine (29)
- tyrosine and tryptophan biosynthesis (29)
- Lipoic acid metabolism (26)
- Methane metabolism (26)
- Vitamin B6 metabolism (21)
- Lysine biosynthesis (18)
- O-Mannosyl glycan biosynthesis (17)
- D-Glutamine and D-glutamate metabolism (16)
- Biotin metabolism (14)
- D-Arginine and D-ornithine metabolism (4)
