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Species
Target Symbol
- BRCA1 (410)
- BTK (301)
- BRCA2 (282)
- GLUCOKINASE (260)
- MENIN (253)
- TUBERIN (252)
- MLH1 (241)
- MSH2 (221)
- RET (194)
- NOTCH3 (164)
- P53 (125)
- NF2 (123)
- FGFR1 (96)
- MSH6 (91)
- LKB1 (87)
- WILMS TUMOR PROTEIN (82)
- DISC1 (76)
- G PROTEIN ALPHA S (75)
- VEGFA (74)
- PDE9A (73)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (71)
- NRG1 (67)
- BDNF (66)
- MORTALITY FACTOR 4 LIKE 2 (65)
- EGFR (64)
- FH (64)
- PLAGL1 (58)
- BETA CATENIN (57)
- CONSTITUTIVE ANDROSTANE RECEPTOR (53)
- SYNTABULIN (53)
- PTEN (51)
- CD46 (49)
- CREM (49)
- FLT4 (49)
- B RAF (47)
- MU OPIOID RECEPTOR (47)
- MYADM (46)
- RUNX1T1 (46)
- ALPHA 1 ANTITRYPSIN (45)
- BIN1 (45)
- XPD (45)
- TRPM3 (44)
- HMGA1 (43)
- KCNJ15 (43)
- NDRG2 (43)
- ST3GAL3 (43)
- CD44 (42)
- MEIS2 (41)
- NAT1 (41)
- UBE2D3 (41)
- BHLHB9 (40)
- DYSTROBREVIN ALPHA (40)
- SSH3BP1 (40)
- ALPHA DYSTROGLYCAN (39)
- SPHK1 (39)
- APC11 (38)
- P311 (38)
- RAD17 (38)
- SLITRK2 (38)
- ARPP21 (37)
- P21 RAS (37)
- TELOMERASE REVERSE TRANSCRIPTASE (37)
- CAMKK2 (36)
- CD36 (36)
- CHRM2 (36)
- EIF5A (36)
- ESTROGEN RELATED RECEPTOR GAMMA (36)
- FGFR2 (36)
- OSBPL9 (36)
- P16INK4A (36)
- SHUGOSHIN (36)
- TGIF (36)
- TTC23 (36)
- CAMK2B (35)
- FHL1 (35)
- MITF (35)
- PAX3 (35)
- PML PROTEIN (35)
- PPHLN1 (35)
- TCF7L2 (35)
- TSPAN4 (35)
- ABLIM2 (34)
- DNMT3B (34)
- ISLR2 (34)
- PTGER3 (34)
- ZBTB20 (34)
- ENSA (33)
- GM CSF RECEPTOR ALPHA (33)
- NCALD (33)
- NEK6 (33)
- PPP2R2B (33)
- RIBONUCLEASE INHIBITOR (33)
- SYTL2 (33)
- TJAP1 (33)
- TPM1 (33)
- YIF1B (33)
- CAMK2D (32)
- CEACAM1 (32)
- CPNE1 (32)
- FGF1 (32)
Tags
Vectors
- pCMV6-Entry (91990)
- pCMV6-AC-GFP (50804)
- pCMV6-XL5 (10779)
- PCMV6-Kan/Neo (6161)
- pCMV6-XL4 (5160)
- pCMV6-AC (3792)
- pCMV6-XL6 (791)
- PCMV6-Neo (246)
- pCMV6-AC-Myc-DDK (152)
- pCMV6-XL5-DDK-His (76)
- pCMV6-Entry2 (19)
- pCMV6-AN-GFP (16)
- pCMV6-AN-RFP (14)
- pCMV6-AN-mBFP (13)
- pCMV6-AN-mGFP (13)
- pCMV6-AN-mRFP (13)
- pCMV6-AC-RFP (11)
- pCMV6-AC-mRFP (11)
- pCMV6-AC-mBFP (10)
- pCMV6-AC-mGFP (10)
- pRMT-tGFP, Promoter-less GFP Reporter Vector (3)
- pLenti-C-Myc-DDK (1)
- pLenti-C-mGFP-P2A-Puro (1)
Mutants
Families
- Druggable Genome (40527)
- Transmembrane (24084)
- Transcription Factors (10767)
- Secreted Protein (6164)
- Protein Kinase (4153)
- Protease (2275)
- ES Cell Differentiation/IPS (2178)
- Stem cell - Pluripotency (2144)
- GPCR (1601)
- Phosphatase (1008)
- Ion Channels: Other (739)
- Adult stem cells (531)
- Nuclear Hormone Receptor (468)
- Embryonic stem cells (413)
- Ion Channels: Potassium (399)
- Cancer stem cells (270)
- Ion Channels: Cys-loop Receptors (228)
- Induced pluripotent stem cells (223)
- P450 (218)
- Stem cell relevant signaling - JAK/STAT signaling pathway (165)
- Ion Channels: Transient receptor potential (145)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (117)
- Ion Channels: Glutamate Receptors (100)
- Stem cell relevant signaling - DSL/Notch pathway (95)
- Stem cell relevant signaling - Wnt Signaling pathway (95)
- Ion Channels: Sodium (83)
- Ion Channels: Calcium (72)
- Ion Channels: ATP Receptors (45)
- Ion Channels: Cyclic nucleotide gated (33)
- Secreted (2)
Pathways
- Metabolic pathways (5778)
- Pathways in cancer (3829)
- MAPK signaling pathway (2144)
- Focal adhesion (1535)
- Regulation of actin cytoskeleton (1532)
- Insulin signaling pathway (1512)
- Cytokine-cytokine receptor interaction (1497)
- Neuroactive ligand-receptor interaction (1465)
- Colorectal cancer (1409)
- Endocytosis (1332)
- Olfactory transduction (1270)
- Ubiquitin mediated proteolysis (1262)
- Neurotrophin signaling pathway (1224)
- Chemokine signaling pathway (1218)
- Calcium signaling pathway (1181)
- Pancreatic cancer (1116)
- Prostate cancer (1115)
- Wnt signaling pathway (1093)
- Endometrial cancer (1036)
- Melanoma (983)
- Natural killer cell mediated cytotoxicity (983)
- ErbB signaling pathway (966)
- Huntington's disease (964)
- Tight junction (925)
- Jak-STAT signaling pathway (920)
- B cell receptor signaling pathway (908)
- Cell cycle (900)
- Fc epsilon RI signaling pathway (888)
- Progesterone-mediated oocyte maturation (884)
- Glioma (877)
- p53 signaling pathway (874)
- T cell receptor signaling pathway (869)
- Purine metabolism (867)
- Axon guidance (848)
- Alzheimer's disease (842)
- Chronic myeloid leukemia (837)
- Melanogenesis (831)
- GnRH signaling pathway (815)
- Leukocyte transendothelial migration (808)
- mTOR signaling pathway (795)
- Vascular smooth muscle contraction (782)
- Cell adhesion molecules (CAMs) (759)
- Oocyte meiosis (752)
- Non-small cell lung cancer (751)
- Renal cell carcinoma (746)
- Apoptosis (740)
- Small cell lung cancer (739)
- Adherens junction (709)
- Thyroid cancer (699)
- Toll-like receptor signaling pathway (697)
- Gap junction (694)
- VEGF signaling pathway (694)
- Fc gamma R-mediated phagocytosis (678)
- Acute myeloid leukemia (649)
- Lysosome (649)
- Dilated cardiomyopathy (644)
- Mismatch repair (643)
- Bladder cancer (641)
- Type II diabetes mellitus (636)
- Glycolysis / Gluconeogenesis (626)
- Long-term depression (614)
- Long-term potentiation (598)
- Systemic lupus erythematosus (580)
- Hematopoietic cell lineage (568)
- Spliceosome (555)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (554)
- Hypertrophic cardiomyopathy (HCM) (543)
- Parkinson's disease (529)
- Primary immunodeficiency (515)
- Adipocytokine signaling pathway (507)
- Pyrimidine metabolism (505)
- Oxidative phosphorylation (503)
- Starch and sucrose metabolism (482)
- Viral myocarditis (481)
- Phosphatidylinositol signaling system (479)
- Antigen processing and presentation (470)
- Amino sugar and nucleotide sugar metabolism (469)
- TGF-beta signaling pathway (464)
- Amyotrophic lateral sclerosis (ALS) (448)
- Basal cell carcinoma (442)
- ECM-receptor interaction (440)
- Epithelial cell signaling in Helicobacter pylori infection (436)
- NOD-like receptor signaling pathway (433)
- Homologous recombination (430)
- PPAR signaling pathway (421)
- Complement and coagulation cascades (418)
- Maturity onset diabetes of the young (404)
- Ribosome (403)
- RIG-I-like receptor signaling pathway (394)
- Galactose metabolism (391)
- Cardiac muscle contraction (383)
- Notch signaling pathway (377)
- Vibrio cholerae infection (372)
- Pathogenic Escherichia coli infection (368)
- Inositol phosphate metabolism (364)
- Glycerophospholipid metabolism (356)
- Dorso-ventral axis formation (348)
- Drug metabolism - cytochrome P450 (325)
- Metabolism of xenobiotics by cytochrome P450 (321)
- Cytosolic DNA-sensing pathway (296)
- Arginine and proline metabolism (288)
- Taste transduction (279)
- Valine (274)
- Glutathione metabolism (270)
- Hedgehog signaling pathway (269)
- Arachidonic acid metabolism (265)
- Retinol metabolism (265)
- RNA degradation (260)
- Autoimmune thyroid disease (256)
- Drug metabolism - other enzymes (256)
- N-Glycan biosynthesis (250)
- Pyruvate metabolism (247)
- Type I diabetes mellitus (241)
- Glycerolipid metabolism (238)
- Tyrosine metabolism (236)
- Nucleotide excision repair (235)
- Fatty acid metabolism (233)
- Lysine degradation (230)
- leucine and isoleucine degradation (227)
- Citrate cycle (TCA cycle) (226)
- Sphingolipid metabolism (226)
- ABC transporters (218)
- Graft-versus-host disease (216)
- Proteasome (211)
- Prion diseases (209)
- Base excision repair (206)
- Cysteine and methionine metabolism (206)
- Tryptophan metabolism (200)
- Allograft rejection (194)
- Alanine (187)
- aspartate and glutamate metabolism (187)
- Porphyrin and chlorophyll metabolism (184)
- Propanoate metabolism (184)
- Androgen and estrogen metabolism (180)
- SNARE interactions in vesicular transport (174)
- Ether lipid metabolism (172)
- Fructose and mannose metabolism (171)
- DNA replication (170)
- Aminoacyl-tRNA biosynthesis (168)
- Butanoate metabolism (166)
- Glycosphingolipid biosynthesis - lacto and neolacto series (156)
- Glycine (150)
- serine and threonine metabolism (150)
- Basal transcription factors (148)
- Regulation of autophagy (147)
- Selenoamino acid metabolism (144)
- Pentose phosphate pathway (140)
- Histidine metabolism (134)
- Glycosaminoglycan degradation (133)
- Nitrogen metabolism (131)
- Asthma (130)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (129)
- O-Glycan biosynthesis (128)
- Linoleic acid metabolism (124)
- Nicotinate and nicotinamide metabolism (122)
- RNA polymerase (120)
- Phenylalanine metabolism (112)
- Pentose and glucuronate interconversions (106)
- beta-Alanine metabolism (104)
- Biosynthesis of unsaturated fatty acids (101)
- Ascorbate and aldarate metabolism (97)
- Keratan sulfate biosynthesis (97)
- Heparan sulfate biosynthesis (96)
- Pantothenate and CoA biosynthesis (95)
- Chondroitin sulfate biosynthesis (93)
- Sulfur metabolism (91)
- One carbon pool by folate (89)
- Riboflavin metabolism (88)
- Primary bile acid biosynthesis (84)
- alpha-Linolenic acid metabolism (84)
- Non-homologous end-joining (83)
- Renin-angiotensin system (83)
- Other glycan degradation (82)
- Glycosphingolipid biosynthesis - globo series (78)
- Glyoxylate and dicarboxylate metabolism (77)
- Steroid biosynthesis (74)
- Terpenoid backbone biosynthesis (74)
- Glycosphingolipid biosynthesis - ganglio series (70)
- leucine and isoleucine biosynthesis (69)
- Circadian rhythm - mammal (67)
- Limonene and pinene degradation (62)
- Taurine and hypotaurine metabolism (61)
- C21-Steroid hormone metabolism (57)
- Caffeine metabolism (50)
- Folate biosynthesis (50)
- Cyanoamino acid metabolism (49)
- Synthesis and degradation of ketone bodies (43)
- Protein export (39)
- Fatty acid biosynthesis (38)
- Fatty acid elongation in mitochondria (38)
- Thiamine metabolism (37)
- Ubiquinone and other terpenoid-quinone biosynthesis (34)
- Phenylalanine (29)
- tyrosine and tryptophan biosynthesis (29)
- Lipoic acid metabolism (26)
- Methane metabolism (26)
- Vitamin B6 metabolism (21)
- Lysine biosynthesis (18)
- D-Glutamine and D-glutamate metabolism (16)
- O-Mannosyl glycan biosynthesis (15)
- Biotin metabolism (14)
- D-Arginine and D-ornithine metabolism (4)
