MSH6 Mutant (A20V), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 6 (E. coli) (MSH6) as transfection-ready DNA
| Mutation | A20V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
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Pou4f2 (tGFP-tagged) - Mouse POU domain class 4 transcription factor 2 (Pou4f2), (10ug)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
Dusp6 (tGFP-tagged) - Mouse dual specificity phosphatase 6 (Dusp6), (10ug)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
Kcnmb1 (tGFP-tagged) - Mouse potassium large conductance calcium-activated channel, subfamily M, beta member 1 (Kcnmb1)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
Sp7 (tGFP-tagged) - Mouse Sp7 transcription factor 7 (Sp7), (10ug)
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Vector | pCMV6-AC-GFP |
- TrueORF®
CTNNB1 Mutant (S33P), Myc-DDK-tagged ORF clone of Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 as transfection-ready DNA
| Mutation | S33P |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
EPHX1 Mutant (R43T), Myc-DDK-tagged ORF clone of Homo sapiens epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1 as transfection-ready DNA
| Mutation | R43T |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
HIF1A Mutant (P582S), Myc-DDK-tagged ORF clone of Homo sapiens hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A), transcript variant 1 as transfection-ready DNA
| Mutation | P582S |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
GPC3 Mutant (C65X), Myc-DDK-tagged ORF clone of Homo sapiens glypican 3 (GPC3), transcript variant 2 as transfection-ready DNA
| Mutation | C65X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (Q62K), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | Q62K |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CSF1R Mutant (Y969C), Myc-DDK-tagged ORF clone of Homo sapiens colony stimulating factor 1 receptor (CSF1R) as transfection-ready DNA
| Mutation | Y969C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MEN1 Mutant (P12L), Myc-DDK-tagged ORF clone of Homo sapiens multiple endocrine neoplasia I (MEN1), transcript variant 2 as transfection-ready DNA
| Mutation | P12L |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CDKN1B Mutant (W76X), Myc-DDK-tagged ORF clone of Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B) as transfection-ready DNA
| Mutation | W76X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Myc-DDK-tagged ORF clone of viral ORF for hypothetical protein HhV6Bgp014 [Human herpesvirus 6], codon optimized for human cell expression, NP_050188
| Type | Virus Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Myc-DDK-tagged ORF clone of viral ORF for rev protein [Human immunodeficiency virus 2], codon optimized for human cell expression, NP_056843
| Type | Virus Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
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Species
Target Symbol
- CD44 (7)
- AKT1 (6)
- ISOCITRATE DEHYDROGENASE (6)
- KRAS (6)
- DNMT1 (5)
- EGFR (5)
- PD-L1 (5)
- TRPA1 (5)
- ABCG2 (4)
- C9ORF72 (4)
- CHRNA3 (4)
- CYP24A1 (4)
- DUSP6 (4)
- FOXM1 (4)
- FYN (4)
- MET (4)
- MITF (4)
- MU OPIOID RECEPTOR (4)
- NRF1 (4)
- OLFM4 (4)
- P53 (4)
- P63 (4)
- PTEN (4)
- PTPRD (4)
- RHOT1 (4)
- SIRT1 (4)
- SLC22A24 (4)
- SOX6 (4)
- SPHK1 (4)
- STAT3 (4)
- TMEM16A (4)
- UCP2 (4)
- VEGFA (4)
- 5HT4 RECEPTOR (3)
- ACSL1 (3)
- ADAM22 (3)
- ADAR1 (3)
- AGTR1A (3)
- ALDH1A1 (3)
- APOLIPOPROTEIN L 1 (3)
- B RAF (3)
- B7H3 (3)
- BIRC5 (3)
- BMPR2 (3)
- BRCA1 (3)
- CAMK2A (3)
- CDK4 (3)
- CERAMIDE SYNTHASE 2 (3)
- CHD4 (3)
- CREB1 (3)
- CXCR4 (3)
- DNMT3A (3)
- DPP6 (3)
- DUSP5 (3)
- FGFR2 (3)
- FGFR3 (3)
- FOXA2 (3)
- FOXO3 (3)
- FOXP3 (3)
- FSTL1 (3)
- GATA6 (3)
- GFAP (3)
- GLYPICAN 3 (3)
- GPBAR1 (3)
- GPR120 (3)
- HER2 (3)
- HES1 (3)
- HIF-1 ALPHA (3)
- IDH2 (3)
- IGFBP1 (3)
- IGFBP7 (3)
- IKZF1 (3)
- IRF1 (3)
- LAMP2 (3)
- LGR5 (3)
- LRP5 (3)
- LRP6 (3)
- MC3R (3)
- MCL1 (3)
- MDM2 (3)
- MLH1 (3)
- MSR1 (3)
- NGF (3)
- NLRP3 (3)
- NOTCH1 (3)
- NOTCH3 (3)
- NRP2 (3)
- NUMB (3)
- P21 RAS (3)
- PDE2A (3)
- PODXL (3)
- PPARA (3)
- RAB5A (3)
- RAB7 (3)
- REST (3)
- RFX4 (3)
- RRM2 (3)
- SIDT1 (3)
- SIDT2 (3)
- SLAMF1 (3)
Vectors
Families
- Druggable Genome (1303)
- Transmembrane (738)
- Transcription Factors (332)
- Secreted Protein (150)
- Protein Kinase (145)
- ES Cell Differentiation/IPS (144)
- GPCR (95)
- Stem cell - Pluripotency (63)
- Protease (45)
- Adult stem cells (35)
- Embryonic stem cells (31)
- Ion Channels: Potassium (29)
- Phosphatase (25)
- Cancer stem cells (24)
- Ion Channels: Other (24)
- Nuclear Hormone Receptor (24)
- Induced pluripotent stem cells (17)
- Stem cell relevant signaling - DSL/Notch pathway (16)
- Ion Channels: Cys-loop Receptors (15)
- Ion Channels: Transient receptor potential (14)
- Stem cell relevant signaling - JAK/STAT signaling pathway (14)
- Ion Channels: Sodium (10)
- P450 (9)
- Ion Channels: Glutamate Receptors (6)
- Ion Channels: Calcium (5)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (5)
- Ion Channels: ATP Receptors (4)
- Stem cell relevant signaling - Wnt Signaling pathway (4)
Pathways
- Pathways in cancer (182)
- Metabolic pathways (146)
- MAPK signaling pathway (101)
- Focal adhesion (93)
- Neuroactive ligand-receptor interaction (86)
- Prostate cancer (80)
- Melanoma (69)
- Regulation of actin cytoskeleton (69)
- Chemokine signaling pathway (68)
- Colorectal cancer (68)
- Endocytosis (68)
- Cytokine-cytokine receptor interaction (65)
- Calcium signaling pathway (62)
- Endometrial cancer (62)
- ErbB signaling pathway (62)
- Neurotrophin signaling pathway (62)
- Glioma (61)
- Jak-STAT signaling pathway (59)
- Renal cell carcinoma (58)
- Non-small cell lung cancer (56)
- Pancreatic cancer (56)
- Axon guidance (54)
- Chronic myeloid leukemia (54)
- Insulin signaling pathway (53)
- T cell receptor signaling pathway (52)
- Natural killer cell mediated cytotoxicity (51)
- Acute myeloid leukemia (49)
- Wnt signaling pathway (49)
- Bladder cancer (46)
- Melanogenesis (46)
- VEGF signaling pathway (46)
- Progesterone-mediated oocyte maturation (44)
- Toll-like receptor signaling pathway (43)
- Fc epsilon RI signaling pathway (42)
- GnRH signaling pathway (42)
- Apoptosis (41)
- B cell receptor signaling pathway (41)
- Gap junction (41)
- Adherens junction (40)
- Small cell lung cancer (40)
- Cell adhesion molecules (CAMs) (39)
- Cell cycle (38)
- Leukocyte transendothelial migration (38)
- Fc gamma R-mediated phagocytosis (37)
- Tight junction (37)
- Alzheimer's disease (36)
- p53 signaling pathway (35)
- Long-term potentiation (34)
- Adipocytokine signaling pathway (32)
- Huntington's disease (31)
- Thyroid cancer (30)
- Type II diabetes mellitus (30)
- mTOR signaling pathway (30)
- Long-term depression (29)
- Vascular smooth muscle contraction (29)
- Hematopoietic cell lineage (28)
- Purine metabolism (28)
- Epithelial cell signaling in Helicobacter pylori infection (27)
- Basal cell carcinoma (26)
- TGF-beta signaling pathway (25)
- Oocyte meiosis (23)
- NOD-like receptor signaling pathway (22)
- Phosphatidylinositol signaling system (22)
- Dorso-ventral axis formation (21)
- Dilated cardiomyopathy (20)
- Glutathione metabolism (20)
- Notch signaling pathway (20)
- Pathogenic Escherichia coli infection (20)
- Amyotrophic lateral sclerosis (ALS) (19)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (19)
- ECM-receptor interaction (19)
- Hypertrophic cardiomyopathy (HCM) (19)
- Lysosome (19)
- Prion diseases (19)
- RIG-I-like receptor signaling pathway (19)
- Ubiquitin mediated proteolysis (19)
- Viral myocarditis (19)
- ABC transporters (17)
- Inositol phosphate metabolism (17)
- Hedgehog signaling pathway (16)
- PPAR signaling pathway (16)
- Systemic lupus erythematosus (14)
- Cytosolic DNA-sensing pathway (13)
- Parkinson's disease (13)
- Sphingolipid metabolism (13)
- Type I diabetes mellitus (13)
- Allograft rejection (12)
- Antigen processing and presentation (12)
- Arachidonic acid metabolism (12)
- Graft-versus-host disease (12)
- Pyrimidine metabolism (12)
- Autoimmune thyroid disease (11)
- Citrate cycle (TCA cycle) (11)
- Glycolysis / Gluconeogenesis (11)
- Maturity onset diabetes of the young (11)
- Metabolism of xenobiotics by cytochrome P450 (11)
- Complement and coagulation cascades (10)
- Drug metabolism - cytochrome P450 (10)
- Fatty acid metabolism (10)
- Glycerophospholipid metabolism (10)
- Lysine degradation (10)
- Cysteine and methionine metabolism (9)
- Homologous recombination (9)
- Pyruvate metabolism (9)
- Retinol metabolism (9)
- Spliceosome (9)
- Base excision repair (8)
- Glycerolipid metabolism (8)
- Starch and sucrose metabolism (8)
- Vibrio cholerae infection (8)
- Drug metabolism - other enzymes (7)
- Linoleic acid metabolism (7)
- Mismatch repair (7)
- Primary immunodeficiency (7)
- Tyrosine metabolism (7)
- Arginine and proline metabolism (6)
- Cardiac muscle contraction (6)
- Ether lipid metabolism (6)
- N-Glycan biosynthesis (6)
- Nicotinate and nicotinamide metabolism (6)
- RNA degradation (6)
- Tryptophan metabolism (6)
- Asthma (5)
- Galactose metabolism (5)
- Oxidative phosphorylation (5)
- Ribosome (5)
- SNARE interactions in vesicular transport (5)
- Taste transduction (5)
- Valine (5)
- Alanine (4)
- Biosynthesis of unsaturated fatty acids (4)
- DNA replication (4)
- Nucleotide excision repair (4)
- Olfactory transduction (4)
- Phenylalanine metabolism (4)
- Renin-angiotensin system (4)
- aspartate and glutamate metabolism (4)
- Fructose and mannose metabolism (3)
- Glycosaminoglycan degradation (3)
- Glycosphingolipid biosynthesis - ganglio series (3)
- Glycosphingolipid biosynthesis - lacto and neolacto series (3)
- Heparan sulfate biosynthesis (3)
- Pantothenate and CoA biosynthesis (3)
- Pentose phosphate pathway (3)
- Propanoate metabolism (3)
- Regulation of autophagy (3)
- alpha-Linolenic acid metabolism (3)
- leucine and isoleucine biosynthesis (3)
- leucine and isoleucine degradation (3)
- Amino sugar and nucleotide sugar metabolism (2)
- Aminoacyl-tRNA biosynthesis (2)
- Androgen and estrogen metabolism (2)
- Butanoate metabolism (2)
- C21-Steroid hormone metabolism (2)
- Circadian rhythm - mammal (2)
- D-Glutamine and D-glutamate metabolism (2)
- Glycine (2)
- Glycosphingolipid biosynthesis - globo series (2)
- Limonene and pinene degradation (2)
- Nitrogen metabolism (2)
- O-Glycan biosynthesis (2)
- Other glycan degradation (2)
- RNA polymerase (2)
- serine and threonine metabolism (2)
- Caffeine metabolism (1)
- Chondroitin sulfate biosynthesis (1)
- Fatty acid biosynthesis (1)
- Folate biosynthesis (1)
- Histidine metabolism (1)
- Keratan sulfate biosynthesis (1)
- Lysine biosynthesis (1)
- Non-homologous end-joining (1)
- Porphyrin and chlorophyll metabolism (1)
- Proteasome (1)
- Riboflavin metabolism (1)
- Selenoamino acid metabolism (1)
- Steroid biosynthesis (1)
- Sulfur metabolism (1)
- Synthesis and degradation of ketone bodies (1)
- Taurine and hypotaurine metabolism (1)
- Terpenoid backbone biosynthesis (1)
- beta-Alanine metabolism (1)
