NEIL1 Human shRNA Plasmid Kit (Locus ID 79661)
CAT#: TR307276
NEIL1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector, 5µg of each construct provided
Need custom shRNA service?
Get a free quote
CNY 4,790.00
货期*
现货
规格
Cited in 2 publications. |
Product images
经常一起买 (2)
NEIL1 mouse monoclonal antibody, clone OTI1D1 (formerly 1D1)
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Product Name | NEIL1 Human shRNA Plasmid Kit (Locus ID 79661) |
Locus ID | 79661 |
UniProt ID | Q96FI4 |
Synonyms | FPG1; hFPG1; NEI1 |
Vector | pRS |
Format | Retroviral plasmids |
Kit Components | NEIL1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector(Gene ID = 79661). 5µg purified plasmid DNA per construct29-mer scrambled shRNA cassette in pRS Vector, TR30012, included for free. |
RefSeq | BC010876, NM_001256552, NM_024608, NR_046311, NM_001352519, NM_001352520, NM_024608.1, NM_024608.2, NM_024608.3, BC010876.1 |
Summary | This gene is a member of the Nei endonuclease VIII-like gene family which encodes DNA glycosylases. The encoded enzyme participates in the DNA repair pathway by initiating base excision repair by removing damaged bases, primarily oxidized pyrimidines. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
shRNA Design | These shRNA constructs were designed against multiple splice variants at this gene locus. To be certain that your variant of interest is targeted, please contact techsupport@origene.com. If you need a special design or shRNA sequence, please utilize our custom shRNA service. |
Performance Guaranteed | OriGene guarantees that the sequences in the shRNA expression cassettes are verified to correspond to the target gene with 100% identity. One of the four constructs at minimum are guaranteed to produce 70% or more gene expression knock-down provided a minimum transfection efficiency of 80% is achieved. Western Blot data is recommended over qPCR to evaluate the silencing effect of the shRNA constructs 72 hrs post transfection. To properly assess knockdown, the gene expression level from the included scramble control vector must be used in comparison with the target-specific shRNA transfected samples. For non-conforming shRNA, requests for replacement product must be made within ninety (90) days from the date of delivery of the shRNA kit. To arrange for a free replacement with newly designed constructs, please contact Technical Services at techsupport@origene.com. Please provide your data indicating the transfection efficiency and measurement of gene expression knockdown compared to the scrambled shRNA control (Western Blot data preferred). |
Citations (2)
The use of this RNAi has been cited in the following citations: |
---|
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase
,Meltem Muftuoglu, Nadja C. Souza-Pinto, Arin Dogan, Maria Aamann, Tinna Stevnsner, Ivana Rybanska, Güldal Kirkali, Miral Dizdaroglu, and Vilhelm A. Bohr,
J. Biol. Chem., Jan 2009; 10.1074/jbc.M807006200.
[NEIL1]
|
Cockayne Syndrome Group B Protein Stimulates Repair of Formamidopyrimidines by NEIL1 DNA Glycosylase
,null,
The Journal of Biological Chemistry
,PubMed ID 19179336
[NEIL1]
|
Documents
Product Manuals |
FAQs |
SDS |
Customer
Reviews
Loading...