Troponin C1 (TNNC1) (NM_003280) Human Recombinant Protein

CAT#: TP710218

Purified recombinant protein of Human troponin C type 1 (slow) (TNNC1), full length, with C-terminal DDK tag, expressed in sf9, 20ug



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CNY 4,020.00


货期*
6周

规格
    • 20 ug

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经常一起买 (1)
TNNC1 mouse monoclonal antibody, clone OTI5H3 (formerly 5H3)
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Specifications

Product Data
Species Human
Expression Host Sf9
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC207014, encoding human full-length TNNC1
Tag C-DDK
Predicted MW 18.2 kDa
Concentration >0.05 µg/µL as determined by microplate BCA method
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer 50 mM Tris-HCl, 100 mM glycine, pH 8.0, 10% glycerol
Note For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage Store at -80°C.
Stability Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq NP_003271
Locus ID 7134
UniProt ID P63316
Refseq Size 705
Cytogenetics 3p21.1
Refseq ORF 483
Synonyms CMD1Z; CMH13; TN-C; TNC; TNNC
Summary Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
Protein Pathways Calcium signaling pathway, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM)
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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