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IL5RA (NM_175727) Human Recombinant Protein
CAT＃: TP322553
Purified recombinant protein of Homo sapiens interleukin 5 receptor, alpha (IL5RA), transcript variant 5, 20 µg
View other "IL5RA" proteins (13)
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>RC222553 representing NM_175727
Red=Cloning site Green=Tags(s) MIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQWKPNPDQEQRNVNLEYQVKIN APKEDDYETRITESKCVTILHKGFSASVRTILQNDHSLLASSWASAELHAPPGSPGTSIVNLTCTTNTTE DNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRYGSWTEECQEYSKDTLGRNIACWFPRTFILSKGRDW LAVLVNGSSKHSAIRPFDQLFALHAIDQINPPLNVTAEIEGTRLSIQWEKPVSAFPIHCFDYEVKIHNTR NGYLQIEKLMTNAFISIIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Tag | C-Myc/DDK |
| Predicted MW | 37.5 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_783854 |
| Locus ID | 3568 |
| UniProt ID | Q01344 |
| Refseq Size | 1956 |
| Cytogenetics | 3p26.2 |
| Refseq ORF | 999 |
| Synonyms | CD125; CDw125; HSIL5R3; IL5R |
| Summary | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. [provided by RefSeq, Jul 2011] |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Jak-STAT signaling pathway |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC403576 | IL5RA HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC406266 | IL5RA HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC406268 | IL5RA HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC424642 | IL5RA HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC425002 | IL5RA HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY403576 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 6 |
CNY 3,080.00 |
|
| LY406266 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 3 |
CNY 3,080.00 |
|
| LY406268 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 5 |
CNY 3,080.00 |
|
| LY424642 | Transient overexpression lysate of interleukin 5 receptor, alpha (IL5RA), transcript variant 1 |
CNY 4,840.00 |
|
| PH305386 | IL5RA MS Standard C13 and N15-labeled recombinant protein (NP_783852) |
CNY 19,520.00 |
|
| PH322553 | IL5RA MS Standard C13 and N15-labeled recombinant protein (NP_783854) |
CNY 14,250.00 |
|
| TP305386 | Recombinant protein of human interleukin 5 receptor, alpha (IL5RA), transcript variant 3, 20 µg |
CNY 2,900.00 |
|
| TP723993 | Human IL5RA Protein, His Tag |
CNY 5,249.00 |
