BCAR1 (NM_001170714) Human Untagged Clone

CAT#: SC329220

BCAR1 (untagged)-Human breast cancer anti-estrogen resistance 1 (BCAR1) transcript variant 1



  "NM_001170714" in other vectors (4)

CNY 17,580.00


货期*
5周

规格
    • 10 ug

Product images

经常一起买 (4)
BCAR1 mouse monoclonal antibody, clone OTI1B1 (formerly 1B1)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms CAS; CAS1; CASS1; CRKAS; P130Cas
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_001170714, the custom clone sequence may differ by one or more nucleotides
ATGCCTGCCAAGCCCTTCCTCTCTTCTGTTCTGCTCTCCTGGAAAGTTCTGGACTTCTCT
GGCCCAGGGCCTCAGGGGACTGGCCAGCCCTGCTCCTGTGGGCACTGGGCAGAGGGACAA
GGCGGACCACCTGAGCCTGCTGGAGGGCCGAACGTGCTGGCCAAAGCGCTCTATGACAAT
GTGGCCGAGTCCCCGGATGAGCTCTCCTTCCGCAAGGGTGACATCATGACGGTGCTGGAG
CAGGACACGCAGGGCCTGGACGGCTGGTGGCTCTGCTCGCTGCATGGGCGCCAGGGCATC
GTGCCTGGGAACCGCCTCAAGATCTTGGTGGGCATGTATGATAAGAAGCCAGCAGGGCCT
GGCCCCGGCCCTCCCGCCACCCCGGCCCAGCCTCAGCCTGGCCTCCATGCCCCAGCGCCT
CCGGCCTCCCAGTACACGCCCATGCTCCCCAACACCTACCAGCCCCAGCCAGACAGCGTC
TACCTGGTGCCCACTCCCAGCAAGGCTCAGCAAGGCCTCTACCAAGTCCCGGGTCCCAGC
CCTCAGTTCCAGTCTCCCCCAGCCAAGCAGACATCCACCTTCTCGAAGCAGACACCCCAT
CACCCGTTTCCCAGCCCGGCCACAGACCTGTACCAGGTGCCCCCAGGGCCTGGAGGCCCT
GCCCAGGATATTTACCAGGTGCCACCTTCTGCCGGGATGGGGCATGACATCTACCAGGTC
CCCCCGTCCATGGACACACGCAGCTGGGAGGGCACGAAGCCCCCGGCAAAGGTGGTGGTG
CCCACCCGCGTGGGGCAGGGCTATGTATACGAGGCCGCCCAGCCGGAGCAGGACGAGTAC
GACATCCCGCGACACCTGCTGGCCCCGGGGCCACAGGACATCTATGATGTGCCCCCGGTT
CGGGGGCTGCTTCCCAGCCAGTATGGCCAGGAGGTGTATGACACACCCCCCATGGCTGTC
AAGGGTCCCAATGGCCGAGACCCGTTGCTGGAGGTGTATGACGTGCCCCCCAGTGTGGAG
AAGGGCCTGCCACCGTCCAACCACCACGCAGTCTACGACGTTCCTCCATCGGTGAGCAAG
GATGTGCCCGATGGCCCACTGCTGCGTGAGGAGACCTACGATGTGCCCCCCGCCTTCGCC
AAGGCCAAGCCCTTTGACCCGGCCCGCACCCCACTGGTACTGGCTGCGCCCCCTCCAGAC
TCCCCGCCGGCCGAGGACGTGTATGACGTGCCGCCCCCGGCTCCTGACCTCTACGACGTG
CCCCCTGGCTTGCGGCGGCCTGGCCCGGGCACCCTGTACGATGTGCCCCGTGAACGGGTG
CTTCCTCCTGAGGTGGCTGATGGTGGCGTGGTCGACAGTGGTGTGTATGCGGTGCCTCCC
CCAGCTGAACGTGAAGCCCCGGCAGAGGGCAAGCGCCTGTCGGCCTCCAGCACCGGCAGC
ACACGCAGCAGCCAGTCTGCGTCCTCCTTGGAGGTGGCAGGGCCGGGCCGGGAACCCCTG
GAGCTGGAAGTTGCTGTGGAGGCCCTGGCACGGCTGCAGCAGGGTGTGAGCGCCACCGTT
GCCCACCTTCTGGACCTGGCAGGCAGCGCCGGTGCGACTGGGAGCTGGCGTAGCCCCTCT
GAGCCACAGGAGCCGCTGGTGCAGGACCTGCAGGCTGCTGTGGCCGCTGTCCAGAGTGCC
GTCCACGAGCTGTTGGAGTTTGCCCGCAGCGCGGTGGGCAATGCTGCCCACACATCTGAC
CGTGCCCTGCATGCCAAGCTTAGCCGGCAGCTGCAGAAGATGGAGGACGTGCACCAGACG
CTGGTGGCACATGGTCAGGCCCTCGACGCTGGCCGGGGAGGCTCTGGAGCCACCCTTGAG
GACCTGGACCGGCTGGTGGCCTGCTCGCGGGCTGTGCCCGAGGACGCCAAGCAGCTGGCC
TCCTTCCTGCACGGCAATGCCTCACTGCTCTTCAGACGGACCAAGGCCACTGCCCCGGGG
CCTGAGGGGGGTGGCACCCTGCACCCCAACCCCACTGACAAGACCAGCAGCATCCAGTCA
CGACCCCTGCCCTCACCCCCTAAGTTCACCTCCCAGGACTCGCCAGATGGGCAGTACGAG
AACAGCGAGGGGGGCTGGATGGAGGACTATGACTACGTCCACCTACAGGGGAAGGAGGAG
TTTGAGAAGACCCAGAAGGAGCTGCTGGAAAAGGGCAGCATCACGCGGCAGGGCAAGAGC
CAGCTGGAGTTGCAGCAGCTGAAGCAGTTTGAACGACTGGAACAGGAGGTGTCACGGCCC
ATAGACCACGACCTGGCCAACTGGACGCCAGCCCAACCCCTGGCCCCGGGGCGAACAGGC
GGCCTGGGGCCCTCGGACCGGCAGCTGCTGCTCTTCTACCTGGAGCAGTGTGAGGCCAAC
CTGACCACACTGACCAACGCCGTGGACGCCTTCTTTACCGCCGTGGCCACCAACCAGCCG
CCCAAGATCTTTGTGGCGCACAGCAAGTTCGTCATCCTCAGCGCCCACAAGCTGGTGTTC
ATCGGGGACACACTGTCACGGCAGGCCAAGGCTGCTGACGTGCGCAGCCAGGTGACCCAC
TACAGCAACCTGCTGTGCGACCTCCTGCGCGGCATCGTGGCCACCACCAAGGCCGCTGCC
TTGCAGTACCCATCGCCTTCCGCGGCCCAGGACATGGTGGAGAGGGTCAAGGAGCTGGGC
CACAGCACCCAGCAGTTCCGCCGCGTCCTAGGCCAGCTGGCAGCCGCCTGA
Restriction Sites Please inquire     
ACCN NM_001170714
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001170714.1, NP_001164185.1
RefSeq Size 3533 bp
RefSeq ORF 2751 bp
Locus ID 9564
UniProt ID P56945
Protein Families Druggable Genome
Protein Pathways Chemokine signaling pathway, Focal adhesion, Leukocyte transendothelial migration, Regulation of actin cytoskeleton
Gene Summary The protein encoded by this gene is a member of the Crk-associated substrate (CAS) family of scaffold proteins, characterized by the presence of multiple protein-protein interaction domains and many serine and tyrosine phosphorylation sites. The encoded protein contains a Src-homology 3 (SH3) domain, a proline-rich domain, a substrate domain which contains 15 repeat of the YxxP consensus phosphorylation motif for Src family kinases, a serine-rich domain, and a bipartite Src-binding domain, which can bind both SH2 and SH3 domains. This adaptor protein functions in multiple cellular pathways, including in cell motility, apoptosis and cell cycle control. Dysregulation of this gene can have a wide range of effects, affecting different pathways, including cardiac development, vascular smooth muscle cells, liver and kidney function, endothelial migration, and cancer. [provided by RefSeq, Sep 2017]
Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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