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Lipoprotein lipase (LPL) (NM_000237) Human Untagged Clone
CAT＃: SC322258
LPL (untagged)-Human lipoprotein lipase (LPL)
CNY 3,656.00
| Cited in 2 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HDLCQ11; LIPD |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322258
GCTCAGCCGGCTCATCAGTCGGTCCGCGCCTTGCAGCTCCTCCAGAGGGACGCGCCCCGA
GATGGAGAGCAAAGCCCTGCTCGTGCTGACTCTGGCCGTGTGGCTCCAGAGTCTGACCGC CTCCCGCGGAGGGGTGGCCGCCGCCGACCAAAGAAGAGATTTTATCGACATCGAAAGTAA ATTTGCCCTAAGGACCCCTGAAGACACAGCTGAGGACACTTGCCACCTCATTCCCGGAGT AGCAGAGTCCGTGGCTACCTGTCATTTCAATCACAGCAGCAAAACCTTCATGGTGATCCA TGGCTGGACGGTAACAGGAATGTATGAGAGTTGGGTGCCAAAACTTGTGGCCGCCCTGTA CAAGAGAGAACCAGACTCCAATGTCATTGTGGTGGACTGGCTGTCACGGGCTCAGGAGCA TTACCCAGTGTCCGCGGGCTACACCAAACTGGTGGGACAGGATGTGGCCCGGTTTATCAA CTGGATGGAGGAGGAGTTTAACTACCCTCTGGACAATGTCCATCTCTTGGGATACAGCCT TGGAGCCCATGCTGCTGGCATTGCAGGAAGTCTGACCAATAAGAAAGTCAACAGAATTAC TGGCCTCGATCCAGCTGGACCTAACTTTGAGTATGCAGAAGCCCCGAGTCGTCTTTCTCC TGATGATGCAGATTTTGTAGACGTCTTACACACATTCACCAGAGGGTCCCCTGGTCGAAG CATTGGAATCCAGAAACCAGTTGGGCATGTTGACATTTACCCGAATGGAGGTACTTTTCA GCCAGGATGTAACATTGGAGAAGCTATCCGCGTGATTGCAGAGAGAGGACTTGGAGATGT GGACCAGCTAGTGAAGTGCTCCCACGAGCGCTCCATTCATCTCTTCATCGACTCTCTGTT GAATGAAGAAAATCCAAGTAAGGCCTACAGGTGCAGTTCCAAGGAAGCCTTTGAGAAAGG GCTCTGCTTGAGTTGTAGAAAGAACCGCTGCAACAATCTGGGCTATGAGATCAGTAAAGT CAGAGCCAAAAGAAGCAGCAAAATGTACCTGAAGACTCGTTCTCAGATGCCCTACAAAGT CTTCCATTACCAAGTAAAGATTCATTTTTCTGGGACTGAGAGTGAAACCCATACCAATCA GGCCTTTGAGATTTCTCTGTATGGCACCGTGGCCGAGAGTGAGAACATCCCATTCACTCT GCCTGAAGTTTCCACAAATAAGACCTACTCCTTCCTAATTTACACAGAGGTAGATATTGG AGAACTACTCATGTTGAAGCTCAAATGGAAGAGTGATTCATACTTTAGCTGGTCAGACTG GTGGAGCAGTCCCGGCTTCGCCATTCAGAAGATCAGAGTAAAAGCAGGAGAGACTCAGAA AAAGGTGATCTTCTGTTCTAGGGAGAAAGTGTCTCATTTGCAGAAAGGAAAGGCACCTGC GGTATTTGTGAAATGCCATGACAAGTCTCTGAATAAGAAGTCAGGCTGAAACTGGGCGAA TCTACAGAACAAAGAACGGCATGTGAATTCTGTGAAGAATGAAGTGGAGGAAGTAACTTT TACAAAACATACCCAGTGTTTGGGGTGTTTCAAAAGTGGATTTTCCTGAATATTAATCCC AGCCCTACCCTTGTTAGTTATTTTAGGAGACAGTCTCAAGCACTAAAAAGTGGCTAATTC AATTTATGGGGTATAGTGGCCAAATAGCACATCCTCCAACGTTAAAAGACAGTGGATCAT GAAAAGTGCTGTTTTGTCCTTTGAGAAAGAAATAATTGTTTGAGCGCAGAGTAAAATAAG GCTCCTTCATGTGGCGTATTGGGCCATAGCCTATAATTGGTTAGAACCTCCTATTTTAAT TGGAATTCTGGATCTTTCGGACTGAGGCCTTCTCAAACTTTACTCTAAGTCTCCAAGAAT ACAGAAAATGCTTTTCCGCGGCACGAATCAGACTCATCTACACAGCAGTATGAATGATGT TTTAGAATGATTCCCTCTTGCTATTGGAATGTGGTCCAGACGTCAACCAGGAACATGTAA CTTGGAGAGGGACGAAGAAAGGGTCTGATAAACACAGAGGTTTTAAACAGTCCCTACCAT TGGCCTGCATCATGACAAAGTTACAAATTCAAGGAGATATAAAATCTAGATCAATTAATT CTTAATAGGCTTTATCGTTTATTGCTTAATCCCTCTCTCCCCCTTCTTTTTTGTCTCAAG ATTATATTATAATAATGTTCTCTGGGTAGGTGTTGAAAATGAGCCTGTAATCCTCAGCTG ACACATAATTTGAATGGTGCAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000237 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000237.1, NP_000228.1 |
| RefSeq Size | 3549 bp |
| RefSeq ORF | 1428 bp |
| Locus ID | 4023 |
| UniProt ID | P06858 |
| Domains | lipase, PLAT |
| Protein Families | Druggable Genome |
| Protein Pathways | Alzheimer's disease, Glycerolipid metabolism, PPAR signaling pathway |
| Gene Summary | LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Endocytosis of very low-density lipoproteins: an unexpected mechanism for lipid acquisition by breast cancer cells
,Lupien, LE;Bloch, K;Dehairs, J;Traphagen, NA;Feng, WW;Dennis, T;Davis, WL;Swinnen, JV;Wells, WA;Smits, NC;Kuemmerle, NB;Miller, TW;Kinlaw, WB;,
J. Lipid Res.
,PubMed ID 31806729
[LPL]
|
|
Endocytosis of very low-density lipoprotein particles: an unexpected mechanism for lipid acquisition by breast cancer cells
,Lupien, LE;Bloch, K;Dehairs, J;Feng, WW;Davis, WL;,
bioRxiv
[LPL]
|
Documents
| Product Manuals |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203766 | LPL (Myc-DDK-tagged)-Human lipoprotein lipase (LPL) |
CNY 5,488.00 |
|
| RC203766L1 | Lenti ORF clone of Human lipoprotein lipase (LPL), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203766L2 | Lenti ORF clone of Human lipoprotein lipase (LPL), mGFP tagged |
CNY 5,890.00 |
|
| RC203766L3 | Lenti ORF clone of Human lipoprotein lipase (LPL), Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC203766L4 | Lenti ORF clone of Human lipoprotein lipase (LPL), mGFP tagged |
CNY 7,888.00 |
|
| RG203766 | LPL (tGFP-tagged) - Human lipoprotein lipase (LPL) |
CNY 7,088.00 |
|
| SC120026 | LPL (untagged)-Human lipoprotein lipase (LPL) |
CNY 3,656.00 |
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