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C5R1 (C5AR1) (NM_001736) Human Untagged Clone
CAT＃: SC322253
C5AR1 (untagged)-Human complement component 5a receptor 1 (C5AR1)
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C5A; C5AR; C5R1; CD88 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for SC322253
CTTCCCTTGGGGCTTTAAAAACCACAGCCCTTGGGCAGGAGGGACCTTCGATCCTCGGGA
GCCCAGGAGACCAGAACATGAACTCCTTCAATTATACCACCCCTGATTATGGGCACTATG ATGACAAGGATACCCTGGACCTCAACACCCCTGTGGATAAAACTTCTAACACGCTGCGTG TTCCAGACATCCTGGCCTTGGTCATCTTTGCAGTCGTCTTCCTGGTGGGAGTGCTGGGCA ATGCCCTGGTGGTCTGGGTGACGGCATTCGAGGCCAAGCGGACCATCAATGCCATCTGGT TCCTCAACTTGGCGGTAGCCGACTTCCTCTCCTGCCTGGCGCTGCCCATCTTGTTCACGT CCATTGTACAGCATCACCACTGGCCCTTTGGCGGGGCCGCCTGCAGCATCCTGCCCTCCC TCATCCTGCTCAACATGTACGCCAGCATCCTGCTCCTGGCCACCATCAGCGCCGACCGCT TTCTGCTGGTGTTTAAACCCATCTGGTGCCAGAACTTCCGAGGGGCCGGCTTGGCCTGGA TCGCCTGTGCCGTGGCTTGGGGTTTAGCCCTGCTGCTGACCATACCCTCCTTCCTGTACC GGGTGGTCCGGGAGGAGTACTTTCCACCAAAGGTGTTGTGTGGCGTGGACTACAGCCACG ACAAACGGCGGGAGCGAGCCGTGGCCATCGTCCGGCTGGTCCTGGGCTTCCTGTGGCCTC TACTCACGCTCACGATTTGTTACACTTTCATCCTGCTCCGGACGTGGAGCCGCAGGGCCA CGCGGTCCACCAAGACACTCAAGGTGGTGGTGGCAGTGGTGGCCAGTTTCTTTATCTTCT GGTTGCCCTACCAGGTGACGGGGATAATGATGTCCTTCCTGGAGCCATCGTCACCCACCT TCCTGCTGCTGAATAAGCTGGACTCCCTGTGTGTCTCCTTTGCCTACATCAACTGCTGCA TCAACCCCATCATCTACGTGGTGGCCGGCCAGGGCTTCCAGGGCCGACTGCGGAAATCCC TCCCCAGCCTCCTCCGGAACGTGTTGACTGAAGAGTCCGTGGTTAGGGAGAGCAAGTCAT TCACGCGCTCCACAGTGGACACTATGGCCCAGAAGACCCAGGCAGTGTAGGCGACAGCCT CATGGGCCACTGTGGCCCGATGTCCCCTTCCTTCCCGGCCATTCTCCCTCTTGTTTTCAC TTCACTTTTCGTGGGATGGTGTTACCTTAGCTAACTAACTCTCCTCCATGTTGCCTGTCT TTCCCAGACTTGTCCCTCCTTTTCCAGCGGGACTCTTCTCATCCTTCCTCATTTGCAAGG TGAACACTTCCTTCTAGGGAGCACCCTCCCACCCCCCACCCCCCCCCACACACCATCTTT CCATCCCAGGCTTTTGAAAAACAAACAGAAACCCGTGTATCTGGGATATTTCCATATGGC AATAGGTGTGAACAGGGAACTCAGAATACAGACAAGTAGAAAGATTCTCGCTTAAAAAAA TGTATTTATTTTATGGCAAGTTGGAAAATATGTAACTGGAATCTCAAAAGTTCTTTGGGA CAAAACAGAAGTCCATGGAGTTATCTAAGCTCTTGTAAGTGAGTTAATTTAAAAAAAAAA AAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_001736 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001736.3, NP_001727.1 |
| RefSeq Size | 2342 bp |
| RefSeq ORF | 1053 bp |
| Locus ID | 728 |
| UniProt ID | P21730 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways | Complement and coagulation cascades, Neuroactive ligand-receptor interaction |
| Gene Summary | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520, PubMed:29300009). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203784 | C5AR1 (Myc-DDK-tagged)-Human complement component 5a receptor 1 (C5AR1) |
CNY 3,656.00 |
|
| RC203784L1 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203784L2 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), mGFP tagged |
CNY 5,890.00 |
|
| RC203784L3 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC203784L4 | Lenti ORF clone of Human complement component 5a receptor 1 (C5AR1), mGFP tagged |
CNY 6,056.00 |
|
| RG203784 | C5AR1 (tGFP-tagged) - Human complement component 5a receptor 1 (C5AR1) |
CNY 5,256.00 |
|
| SC119072 | C5AR1 (untagged)-Human complement component 5a receptor 1 (C5AR1) |
CNY 3,656.00 |
