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LRP6 (NM_002336) Human Untagged Clone
CAT＃: SC315373
LRP6 (untagged)-Human low density lipoprotein receptor-related protein 6 (LRP6)
CNY 16,560.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ADCAD2; STHAG7 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_002336 edited
CTGGGAAGTATGAGCGTGCAGCCCTGCCGCTGCGGCGGCCGCCCCGGCTCCTCGCCTCCC CCACTTCTGGCCACCCCTCGCCGGTGAGAGAAGAGAACGCGAGAAGGGAAGATGGGGGCC GTCCTGAGGAGCCTCCTGGCCTGCAGCTTCTGTGTGCTCCTGAGAGCGGCCCCTTTGTTG CTTTATGCAAACAGACGGGACTTGCGATTGGTTGATGCTACAAATGGCAAAGAGAATGCT ACGATTGTAGTTGGAGGCTTGGAGGATGCAGCTGCGGTGGACTTTGTGTTTAGTCATGGC TTGATATACTGGAGTGATGTCAGCGAAGAAGCCATTAAACGAACAGAATTTAACAAAACT GAGAGTGTGCAGAATGTTGTTGTTTCTGGATTATTGTCCCCCGATGGGCTGGCATGTGAT TGGCTTGGAGAAAAATTGTACTGGACAGATTCTGAAACTAATCGGATTGAAGTTTCTAAT TTAGATGGATCTTTACGAAAAGTTTTATTTTGGCAAGAGTTGGATCAACCCAGAGCTATT GCCTTAGATCCTTCAAGTGGGTTCATGTACTGGACAGACTGGGGAGAAGTGCCAAAGATA GAACGTGCTGGAATGGATGGTTCAAGTCGCTTCATTATAATAAACAGTGAAATTTACTGG CCAAATGGACTGACTTTGGATTATGAAGAACAAAAGCTTTATTGGGCAGATGCAAAACTT AATTTCATCCACAAATCAAATCTGGATGGAACAAATCGGCAGGCAGTGGTTAAAGGTTCC CTTCCACATCCTTTTGCCTTGACGTTATTTGAGGACATATTGTACTGGACTGACTGGAGC ACACACTCCATTTTGGCTTGCAACAAGTATACTGGTGAGGGTCTGCGTGAAATCCATTCT GACATCTTCTCTCCCATGGATATACATGCCTTCAGCCAACAGAGGCAGCCAAATGCCACA AATCCATGTGGAATTGACAATGGGGGTTGTTCCCATTTGTGTTTGATGTCTCCAGTCAAG CCTTTTTATCAGTGTGCTTGCCCCACTGGGGTCAAACTCCTGGAGAATGGAAAAACCTGC AAAGATGGTGCCACAGAATTATTGCTTTTAGCTCGAAGGACAGACTTGAGACGCATTTCT TTGGATACACCAGATTTTACAGACATTGTTCTGCAGTTAGAAGACATCCGTCATGCCATT GCCATAGATTACGATCCTGTGGAAGGCTACATCTACTGGACTGATGATGAAGTGAGGGCC ATACGCCGTTCATTTATAGATGGATCTGGCAGTCAGTTTGTGGTCACTGCTCAAATTGCC CATCCTGATGGTATTGCTGTGGACTGGGTTGCACGAAATCTTTATTGGACAGACACTGGC ACTGATCGAATAGAAGTGACAAGGCTCAATGGGACCATGAGGAAGATCTTGATTTCAGAG GACTTAGAGGAACCCCGGGCTATTGTGTTAGATCCCATGGTTGGGTACATGTATTGGACT GACTGGGGAGAAATTCCGAAAATTGAGCGAGCAGCTCTGGATGGTTCTGACCGTGTAGTA TTGGTTAACACTTCTCTTGGTTGGCCAAATGGTTTAGCCTTGGATTATGATGAAGGCAAA ATATACTGGGGAGATGCCAAAACAGACAAGATTGAGGTTATGAATACTGATGGCACTGGG AGACGAGTACTAGTGGAAGACAAAATTCCTCACATATTTGGATTTACTTTGTTGGGTGAC TATGTTTACTGGACTGACTGGCAGAGGCGTAGCATTGAAAGAGTTCATAAACGAAGTGCA GAGAGGGAAGTGATCATAGATCAGCTGCCTGACCTCATGGGCCTAAAGGCTACAAATGTT CATCGAGTGATTGGTTCCAACCCCTGTGCTGAGGAAAACGGGGGATGTAGCCATCTCTGC CTCTATAGACCTCAGGGCCTTCGCTGTGCTTGCCCTATTGGCTTTGAACTCATCAGTGAC ATGAAGACCTGCATTGTCCCAGAGGCTTTCCTTTTGTTTTCACGGAGAGCAGATATCAGA CGAATTTCTCTGGAAACAAACAATAATAATGTGGCTATTCCACTCACTGGTGTCAAAGAA GCTTCTGCTTTGGATTTTGATGTGACAGACAACCGAATTTATTGGACTGATATATCACTC AAGACCATCAGCAGAGCCTTTATGAATGGCAGTGCACTGGAACATGTGGTAGAATTCGGC TTAGATTATCCAGAAGGCATGGCAGTAGACTGGCTTGGGAAGAACTTGTACTGGGCAGAC ACAGGAACGAATCGAATTGAGGTGTCAAAGTTGGATGGGCAGCACCGACAAGTTTTGGTG TGGAAAGACCTAGATAGTCCCAGAGCTCTCGCGTTGGACCCTGCCGAAGGATTTATGTAT TGGACTGAATGGGGTGGAAAACCTAAGATAGACAGAGCTGCAATGGATGGAAGTGAACGT ACTACCTTAGTTCCAAATGTGGGGCGGGCAAACGGCCTAACTATTGATTATGCTAAAAGG AGGCTTTATTGGACAGACCTGGACACCAACTTAATAGAATCTTCAAATATGCTTGGGCTC AACCGTGAAGTTATAGCAGATGACTTGCCTCATCCTTTTGGCTTAACTCAGTACCAAGAT TATATCTACTGGACGGACTGGAGCCGACGCAGCATTGAGCGTGCCAACAAAACCAGTGGC CAAAACCGCACCATCATTCAGGGCCATTTGGATTATGTGATGGACATCCTCGTCTTTCAC TCATCTCGACAGTCAGGGTGGAATGAATGTGCTTCCAGCAATGGGCACTGCTCCCACCTC TGCTTGGCTGTGCCAGTTGGGGGTTTTGTTTGTGGATGCCCTGCCCACTACTCTCTTAAT GCTGACAACAGGACTTGTAGTGCTCCTACGACTTTCCTGCTCTTCAGTCAAAAGAGTGCC ATCAACCGCATGGTGATTGATGAACAACAGAGCCCCGACATCATCCTTCCCATCCACAGC CTTCGGAATGTCCGGGCCATTGACTATGACCCACTGGACAAGCAACTCTATTGGATTGAC TCACGACAAAACATGATCCGAAAGGCACAAGAAGATGGCAGCCAGGGCTTTACTGTGGTT GTGAGCTCAGTTCCGAGTCAGAACCTGGAAATACAACCCTATGACCTCAGCATTGATATT TACAGCCGCTACATCTACTGGACTTGTGAGGCTACCAATGTCATTAATGTGACAAGATTA GATGGGAGATCAGTTGGAGTGGTGCTGAAAGGCGAGCAGGACAGACCTCGAGCCATTGTG GTAAACCCAGAGAAAGGGTATATGTATTTTACCAATCTTCAGGAAAGGTCTCCTAAAATT GAACGGGCTGCTTTGGATGGGACAGAACGGGAGGTCCTCTTTTTCAGTGGCTTAAGTAAA CCAATTGCTTTAGCCCTTGATAGCAGGCTGGGCAAGCTCTTTTGGGCTGATTCAGATCTC CGGCGAATTGAAAGCAGTGATCTCTCAGGTGCTAACCGGATAGTATTAGAAGACTCCAAT ATCTTGCAGCCTGTGGGACTTACTGTGTTTGAAAACTGGCTCTATTGGATTGATAAACAG CAGCAAATGATTGAAAAAATTGACATGACAGGTCGAGAGGGTAGAACCAAAGTCCAAGCT CGAATTGCCCAGCTTAGTGACATTCATGCAGTAAAGGAGCTGAACCTTCAAGAATACAGA CAGCACCCTTGTGCTCAGGATAATGGTGGCTGTTCACATATTTGTCTTGTAAAGGGGGAT GGTACTACAAGGTGTTCTTGCCCCATGCACCTGGTTCTACTTCAAGATGAGCTATCATGT GGAGAACCTCCAACATGTTCTCCTCAGCAGTTTACTTGTTTCACGGGGGAAATTGACTGT ATCCCTGTGGCTTGGCGGTGCGATGGGTTTACTGAATGTGAAGACCACAGTGATGAACTC AATTGTCCTGTATGCTCAGAGTCCCAGTTCCAGTGTGCCAGTGGGCAGTGTATTGATGGT GCCCTCCGATGCAATGGAGATGCAAACTGCCAGGACAAATCAGATGAGAAGAACTGTGAA GTGCTTTGTTTAATTGATCAGTTCCGCTGTGCCAATGGTCAGTGCATTGGAAAGCACAAG AAGTGTGATCATAATGTGGATTGCAGTGACAAGTCAGATGAACTGGATTGTTATCCGACT GAAGAACCAGCACCACAGGCCACCAATACAGTTGGTTCTGTTATTGGCGTAATTGTCACC ATTTTTGTGTCTGGAACTGTATACTTTATCTGCCAGAGGATGTTGTGTCCACGTATGAAG GGAGATGGGGAAACTATGACTAATGACTATGTAGTTCATGGACCAGCTTCTGTGCCTCTT GGTTATGTGCCACACCCAAGTTCTTTGTCAGGATCTCTTCCAGGAATGTCTCGAGGTAAA TCAATGATCAGCTCCCTCAGTATCATGGGGGGAAGCAGTGGACCCCCCTATGACCGAGCC CATGTTACAGGAGCATCATCAAGTAGTTCTTCAAGCACCAAAGGCACTTACTTCCCTGCA ATTTTGAACCCTCCACCATCCCCAGCCACAGAGCGATCACATTACACTATGGAATTTGGA TATTCTTCAAACAGTCCTTCCACTCATAGGTCATACAGCTACAGGCCATATAGCTACCGG CACTTTGCACCCCCCACCACACCCTGCAGCACAGATGTTTGTGACAGTGACTATGCTCCT AGTCGGAGAATGACCTCAGTGGCAACAGCCAAGGGCTATACCAGTGACTTGAACTATGAT TCAGAACCTGTGCCCCCACCTCCCACACCCCGAAGCCAATACTTGTCAGCAGAGGAGAAC TATGAAAGCTGCCCACCTTCTCCATACACAGAGAGGAGCTATTCTCATCACCTCTACCCA CCGCCACCCTCTCCCTGTACAGACTCCTCCTGAGGAGGGGCCCTCCTCCTCTGACTGCCT CCAACGTAAAAATGTAAATATAAATTTGGTTGAGATCTGGAGGGGGGGAGGGAGCTATTA GAGAAGGATGAGGCAGACCATGTACAGTTAAAATTATAAAATGGGGTAGGGAATACTGGA GATATTTGTACAGAAGAAAAGGATATTTATATATTTTCTTAAAACAGCAGATTTGCTGCT TGTGCCATAAAAGTTTGTATAAAAAAAATTTGTACTAAAAGTTTTATTTTTGCAAACTAA ATACACAAAGCATGCCTTAAACCCAGTGAAGCAACTGAGTACAAAGGAAACAGGAATAAT AAAGGCATCACTGACCAGGAATATCTGGGCTTTATTGATACCAAAAATAAAAAAAAAAAA AAAAAA >Reverse primer walk for NM_002336 unedited
GCCTAGTTCATAAACTTTTCTAAACTCCTCTAATTAGAAACTTCATCCGATTAGTTTCAG AATCTGTCCAGTACAATTTTTCTCCAAGCCAATCACATGCCAGCCCATCGGGGGACAATA ATCCAGAAACAACAACATTCTGCACACTCTCAGTTTTGTTAAATTCTGTTCGTTTAATGG CTTCTTCGCTGACATCACTCCAGTATATCAAGCCATGACTAAACACAAAGTCCACCGCAG CTGCATCCTCCAAGCCTCCAACTACAATCGTAGCATTCTCTTTGCCATTTGTAGCATCAA CCAATCGCAAGTCCCGTCTGTTTGCATAAAGCAACAAAGGGGCCGCTCTCAGGAGCACAC AGAAGCTGCAGGCCAGGAGGCTCCTCAGGACGGCCCCCATCTTCCCTTCTCGCGTTCTCT TCTCTCACCGGCGAGGGGTGGCCAGAAGTGGGGGAGGCGAGGAGCCGGGGCGGCCGCCGC AGCGGCAGGGCTGCACGCTCATACTTCCCAGCCTCGTGCCGAATTCGCGGCCGCCCTATA GTGAGTCGTATTACANAATTCTGACGGTTCACTAAACGAGCTCTGCTTATATAGACCTCC CACCGTACACGCCTACCGCCCATTTGCGTCAACGGGGCGGGGTTATTACGACATTTTGGA AGTCCNGTTGATTTTGGTGCCAAACANAACTCCATTGACGTCNAATGGGTGGAGACTTGG AAATCCCCGTGAGTCAAACCGCTATCCACGCCCATTGGTGTACTGCCAAAACCGCATCAC CATGGTAATAGCGATGACTAATACGTAGATGTACTGCCCAGTAAGAAAGTCCCGTAAGGT CATGTACTGGGCATAATGCCAGGCGGGCCATTTACCGTCTTTGACGTAAC >Reverse primer walk for NM_002336 unedited
GGATCTATTACTTTTTACCTGGTAGCATCANAGNAGGAGGCCCCTCCTCAGNAGAGTCTG TACAGGGAGAGGGTGGCGGTGGGTAGAGGTGATGAGAATAGCTCCTCTCTGTGTATGGAG AAGGTGGGCAGCTTTCATAGTTCTCCTCTGCTGACAAGTATTGGCTTCGGGGTGTGGGAG GTGGGGGCACAGGTTCTGAATCATAGTTCAAGTCACTGGTATAGCCCTTGGCTGTTGCCA CTGAGGTCATTCTCCGACTAGGAGCATAGTCACTGTCACAAACATCTGTGCTGCAGGGTG TGGTGGGGGGTGCAAAGTGCCGGTAGCTATATGGCCTGTAGCTGTATGACCTATGAGTGG AAGGACTGTTTGAAGAATATCCAAATTCCATAGTGTAATGTGATCGCTCTGTGGCTGGGG ATGGTGGAGGGTTCAAAATTGCAGGGAAGTAAGTGCCTTTGGTGCTTGAAGAACTACTTG ATGATGCTCCTGTAACATGGGCTCGGTCATAGGGGGGTCCACTGCTTCCCCCCATGATAC TGAGGGAGCTGATCATTGATTTACCTCGAGACATTCCTGGAAGAGATCCTGACAAAGAAC TTGNGTGTGGCACATAACCAAGAGGCACAGAAGCTGGTCCATGAACTACATAGTCATTAG TCATAGTTTCCCCCTCTCCCTTCATACGTGGACACAACATCCTCTGNCAGATAAAGTATA CAGTTCCAGACCCAAAAATGGTGACAATTACGCCAATACCGAACCAACTGTATTGGTGGC CTGTGGTGCTTGGTTCTCCATCGGAAAACATCCCATTCAATCTGCCTGTCCCTGCAATCC CCTTAAGATCCCCCTCCTGGGGCTTTCCATGCCCCTGCCATTGGCACCACGG |
| Restriction Sites | Please inquire |
| ACCN | NM_002336 |
| Insert Size | 5300 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002336.1, NP_002327.1 |
| RefSeq Size | 5301 bp |
| RefSeq ORF | 4842 bp |
| Locus ID | 4040 |
| UniProt ID | O75581 |
| Domains | ldl_recept_b, ldl_recept_a, EGF, EGF |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Wnt signaling pathway |
| Gene Summary | This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218918 | LRP6 (Myc-DDK-tagged)-Human low density lipoprotein receptor-related protein 6 (LRP6) |
CNY 16,552.00 |
|
| RC218918L1 | Lenti ORF clone of Human low density lipoprotein receptor-related protein 6 (LRP6), Myc-DDK-tagged |
CNY 17,960.00 |
|
| RC218918L2 | Lenti ORF clone of Human low density lipoprotein receptor-related protein 6 (LRP6), mGFP tagged |
CNY 18,952.00 |
|
| RC218918L3 | Lenti ORF clone of Human low density lipoprotein receptor-related protein 6 (LRP6), Myc-DDK-tagged |
CNY 17,960.00 |
|
| RC218918L4 | Lenti ORF clone of Human low density lipoprotein receptor-related protein 6 (LRP6), mGFP tagged |
CNY 18,952.00 |
|
| RG218918 | LRP6 (tGFP-tagged) - Human low density lipoprotein receptor-related protein 6 (LRP6) |
CNY 18,152.00 |
