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Repulsive Guidance Molecule C (HFE2) (NM_213653) Human Untagged Clone
CAT＃: SC308698
HFE2 (untagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a
CNY 3,656.00
CNY 6,840.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HFE2; HFE2A; JH; RGMC |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_213653 edited
ATGGGGGAGCCAGGCCAGTCCCCTAGTCCCAGGTCCTCCCATGGCAGTCCCCCAACTCTA AGCACTCTCACTCTCCTGCTGCTCCTCTGTGGACATGCTCATTCTCAATGCAAGATCCTC CGCTGCAATGCTGAGTACGTATCGTCCACTCTGAGCCTTAGAGGTGGGGGTTCATCAGGA GCACTTCGAGGAGGAGGAGGAGGAGGCCGGGGTGGAGGGGTGGGCTCTGGCGGCCTCTGT CGAGCCCTCCGCTCCTATGCGCTCTGCACTCGGCGCACCGCCCGCACCTGCCGCGGGGAC CTCGCCTTCCATTCGGCGGTACATGGCATCGAAGACCTGATGATCCAGCACAACTGCTCC CGCCAGGGCCCTACAGCCCCTCCCCCGCCCCGGGGCCCCGCCCTTCCAGGCGCGGGCTCC GGCCTCCCTGCCCCGGACCCTTGTGACTATGAAGGCCGGTTTTCCCGGCTGCATGGTCGT CCCCCGGGGTTCTTGCATTGCGCTTCCTTCGGGGACCCCCATGTGCGCAGCTTCCACCAT CACTTTCACACATGCCGTGTCCAAGGAGCTTGGCCTCTACTGGATAATGACTTCCTCTTT GTCCAAGCCACCAGCTCCCCCATGGCGTTGGGGGCCAACGCTACCGCCACCCGGAAGCTC ACCATCATATTTAAGAACATGCAGGAATGCATTGATCAGAAGGTGTATCAGGCTGAGGTG GATAATCTTCCTGTAGCCTTTGAAGATGGTTCTATCAATGGAGGTGACCGACCTGGGGGA TCCAGTTTGTCGATTCAAACTGCTAACCCTGGGAACCATGTGGAGATCCAAGCTGCCTAC ATTGGCACAACTATAATCATTCGGCAGACAGCTGGGCAGCTCTCCTTCTCCATCAAGGTA GCAGAGGATGTGGCCATGGCCTTCTCAGCTGAACAGGACCTGCAGCTCTGTGTTGGGGGG TGCCCTCCAAGTCAGCGACTCTCTCGATCAGAGCGCAATCGTCGGGGAGCTATAACCATT GATACTGCCAGACGGCTGTGCAAGGAAGGGCTTCCAGTGGAAGATGCTTACTTCCATTCC TGTGTCTTTGATGTTTTAATTTCTGGTGATCCCAACTTTACCGTGGCAGCTCAGGCAGCA CTGGAGGATGCCCGAGCCTTCCTGCCAGACTTAGAGAAGCTGCATCTCTTCCCCTCAGAT GCTGGGGTTCCTCTTTCCTCAGCAACCCTCTTAGCTCCACTCCTTTCTGGGCTCTTTGTT CTGTGGCTTTGCATTCAGTAAGGGGACCATCAGTCCCATTACTAGTTTGGAAATGATTTG GAGATACAGATTGGCATAGAAGAATGTAAAGAATCATTAAAGGAAGCAGGGCCTAGGAGA CACGTGAAACAATGACATTATCCAGAGTCAGATGAGGCTGCAGTCCAGGGTTGAAATTAT CACAGAATAAGGATTCTGGGCAAGGTTACTGCATTCCGGATCTCTGTGGGGCTCTTCACC AATTTTTCCAGCCTCATTTATAGTAAACAAATTGTTCTAATCCATTTACTGCAGATTTCA CCCTTATAAGTTTAGAGGTCATGAAGGTTTTAATGATCAGTAAAGATTTAAGGGTTGAGA TTTTTAAGAGGCAAGAGCTGAAAGCAGAAGACATGATCATTAGCCATAAGAAACTCAAAG GAGGAAGACATAATTAGGGAAAGAAGTCTATTTGATGAATATGTGTGTGTAAGGTATGTT CTGCTTTCTTGATTCAAAAATGAAGCAGGCATTGTCTAGCTCTTAGGTGAAGGGAGTCTC TGCTTTTGAAGAATGGCACAGGTAGGACAGAAGTATCATCCCTACCCCCTAACTAATCTG TTATTAAAGCTACAAATTCTTCACACCAWMAAAAAAAAAAAAAAA >OriGene 5' read for NM_213653 unedited
NNNNGGGGCGTCAAATATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAG ATGGGGGAGCCAGGCCAGTCCCCTAGTCCCAGGTCCTCCCATGGCAGTCCCCCAACTCTA AGCACTCTCACTCTCCTGCTGCTCCTCTGTGGACATGCTCATTCTCAATGCAAGATCCTC CGCTGCAATGCTGAGTACGTATCGTCCACTCTGAGCCTTAGAGGTGGGGGTTCATCAGGA GCACTTCGAGGAGGAGGAGGAGGAGGCCGGGGTGGAGGGGTGGGCTCTGGCGGCCTCTGT CGAGCCCTCCGCTCCTATGCGCTCTGCACTCGGCGCACCGCCCGCACCTGCCGCGGGGAC CTCGCCTTCCATTCGGCGGTACATGGCATCGAAGACCTGATGATCCAGCACANACTGNCN NTCCCGCCAGGGCCCTACAGCCCCTCCCCCGCCCCNCNNGGGGCCCCCCNNGCCCTTCCA GGCGCGNGNNGCTCCGGCCTCCCTGCCCCGGACCCTTGTGACTATGAAGGCCGGTTTTCC CGGCTGCATGGTCGTCCCCCGGGGTTCTTGCATTGCGCTTCCTTCGGGGACCCCCATGTG CGCAGCTTCCACCATCACTTTCACACATGCCGTGTCCAAGGAGCTTGGCCTCTACTGGAT AATGACTTCCTCTTTGTCCAAGCCACCAGCTCCCCCATGGCGTTGGGGGCCAACGCTACC GCCACCCGGAAGCTCACCATCATATTTAAGAACATGCAGGAATGCATTGATCAGAAGGTG TATCANGCTGAGGTGGATAATCTTCCTGTAGCCTTTGAAGATGGTTCTATCAATGGAGGT GACCGACCTGGGGGATCCAGTTTGTCN >Forward primer walk for NM_213653 unedited
GCCCCCCCTGGCGTTGGGGGCCAACNCTACCGCCACCCGGNAAGCTCACCATCATATTTA AGAACATGCAGGAATGCATTGATCAGAAGGTGTATCAGGCTGAGGTGGATAATCTTCCTG TAGCCTTTGAAGATGGTTCTATCAATGGAGGTGACCGACCTGGGGGATCCAGTTTGTCGA TTCAAACTGCTAACCCTGGGAACCATGTGGAGATCCAAGCTGCCTACATTGGCACAACTA TAATCATTCGGCAGACAGCTGGGCAGCTCTCCTTCTCCATCAAGGTAGCAGAGGATGTGG CCATGGCCTTCTCAGCTGAACAGGACCTGCAGCTCTGTGTTGGGGGGTGCCCTCCAAGTC AGCGACTCTCTCGATCAGAGCGCAATCGTCGGGGAGCTATAACCATTGATACTGCCAGAC GGCTGTGCAAGGAAGGGCTTCCAGTGGAAGATGCTTACTTCCATTCCTGTGTCTTTGATG TTTTAATTTCTGGTGATCCCAACTTTACCGTGGCAGCTCANGCAGCACTGGAGGATGCCC GAGCCTTCCTGCCAGACTTAGAGAAGCTGCATCTCTTCCCCTCAGATGCTGGGGTTCCTC TTTCCTCAGCAACCCTCTTAGCTCCACTCCTTTCTGGGCTCTTTGTTCTGTGGCTTTGCA TTCAGTAAGGGGACCATCAGTCCCATTACTAGTTTGGAAATGATTTGGAGATACAGATTG GCATAGAAGAAATGTAAGAATCATTAAAGGAAGCAGGGCCTANGAGACACGTGAAACAAT GACATTATCCAGAGTCAGATGAAGCTGCAGTCCANGGGTGAAATTATCACAGAATAAGGA TTCTGGGNCAGGGTACTGCATTCCGNATCTCTGTGGGGCTCTTCACCAATTTTCCAGCCT CATTATAGTAAACAAATTGTCTN |
| Restriction Sites | Please inquire |
| ACCN | NM_213653 |
| Insert Size | 1900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_213653.2, NP_998818.1 |
| RefSeq Size | 2128 bp |
| RefSeq ORF | 1281 bp |
| Locus ID | 148738 |
| UniProt ID | Q6ZVN8 |
| Protein Families | Transmembrane |
| Gene Summary | The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30. [provided by RefSeq, Oct 2015] Transcript Variant: This variant (a) represents the longest transcript, and encodes the longest isoform (a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217954 | HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a |
CNY 5,856.00 |
|
| RC217954L3 | Lenti-ORF clone of HFE2 (Myc-DDK-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a |
CNY 5,890.00 |
|
| RC217954L4 | Lenti-ORF clone of HFE2 (mGFP-tagged)-Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a |
CNY 5,890.00 |
|
| RG217954 | HFE2 (tGFP-tagged) - Human hemochromatosis type 2 (juvenile) (HFE2), transcript variant a |
CNY 7,456.00 |
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