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BIN1 (NM_139350) Human Untagged Clone
CAT＃: SC128163
BIN1 (untagged)-Human bridging integrator 1 (BIN1), transcript variant 9
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AMPH2; AMPHL; CNM2; SH3P9 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_139350 edited
GCGGCGTGGAGCGGCAGCCGGTCTGGACGCGCGGCCGGGGCTGGGGGCTGGGAGCGCGGC GCGCAAGATCTCCCCGCGCGAGAGCGGCCCCTGCCACCGGGCGAGGCCTGCGCCGCGATG GCAGAGATGGGCAGTAAAGGGGTGACGGCGGGAAAGATCGCCAGCAACGTGCAGAAGAAG CTCACCCGCGCGCAGGAGAAGGTTCTCCAGAAGCTGGGGAAGGCAGATGAGACCAAGGAT GAGCAGTTTGAGCAGTGCGTCCAGAATTTCAACAAGCAGCTGACGGAGGGCACCCGGCTG CAGAAGGATCTCCGGACCTACCTGGCCTCCGTCAAAGCCATGCACGAGGCTTCCAAGAAG CTGAATGAGTGTCTGCAGGAGGTGTATGAGCCCGATTGGCCCGGCAGGGATGAGGCAAAC AAGATCGCAGAGAACAACGACCTGCTGTGGATGGATTACCACCAGAAGCTGGTGGACCAG GCGCTGCTGACCATGGACACGTACCTGGGCCAGTTCCCCGACATCAAGTCACGCATTGCC AAGCGGGGGCGCAAGCTGGTGGACTACGACAGTGCCCGGCACCACTACGAGTCCCTTCAA ACCGCCAAAAAGAAGGATGAAGCCAAAATTGCCAAGGCCGAGGAGGAGCTCATCAAAGCC CAGAAGGTGTTTGAGGAGATGAATGTGGATCTGCAGGAGGAGCTGCCGTCCCTGTGGAAC AGCCGCGTAGGTTTCTACGTCAACACGTTCCAGAGCATCGCGGGCCTGGAGGAAAACTTC CACAAGGAGATGAGCAAGCTCAACCAGAACCTCAATGATGTGCTGGTCGGCCTGGAGAAG CAACACGGGAGCAACACCTTCACGGTCAAGGCCCAGCCCAGTGACAACGCGCCTGCAAAA GGGAACAAGAGCCCTTCGCCTCCAGATGGCTCCCCTGCCGCCACCCCCGAGATCAGAGTC AACCACGAGCCAGAGCCGGCTGGCGGGGCCACGCCCGGGGCCACCCTCCCCAAGTCCCCA TCTCAGCCAGCAGAGGCCTCGGAGGTGGCGGGTGGGACCCAACCTGCGGCTGGAGCCCAG GAGCCAGGGGAGACGGCGGCAAGTGAAGCAGCCTCCAGCTCTCTTCCTGCTGTCGTGGTG GAGACCTTCCCAGCAACTGTGAATGGCACCGTGGAGGGCGGCAGTGGGGCCGGGCGCTTG GACCTGCCCCCAGGTTTCATGTTCAAGGTACAGGCCCAGCACGACTACACGGCCACTGAC ACAGACGAGCTGCAGCTCAAGGCTGGTGATGTGGTGCTGGTGATCCCCTTCCAGAACCCT GAAGAGCAGGATGAAGGCTGGCTCATGGGCGTGAAGGAGAGCGACTGGAACCAGCACAAG GAGCTGGAGAAGTGCCGTGGCGTCTTCCCCGAGAACTTCACTGAGAGGGTCCCATGACGG CGGGGCCCAGGCAGCCTCCGGGCGTGTGAAGAACACCTCCTCCCGAAAAATGTGTGGTTC TTTTTTTTGTTTTGTTTTCGTTTTTCATCTTTTGAAGAGCAAAGGGAAATCAAGAGGAGA CCCCCAGGCAGAGGGGCGTTCTCCCAAAGATTAGGTCGTTTTCCAAAGAGCCGCGTCCCG GCAAGTCCGGCGGAATTCACCAGTGTTCCTGAAGCTGCTGTGTCCTCTAGTTGAGTTTCT GGCGCCCCTGCCTGTGCCCGCATGTGTGCCTGGCCGCAGGGCGGGGCTGGGGGCTGCCGA GCCACCATGCTTGCCTGAAGCTTCGGCCGCGCCACCCGGGCAAGGGTCCTCTTTTCCTGG CAGCTGCTGTGGGTGGGGCCCAGACACCAGCCTAGCCTGGCTCTGCCCCGCAGACGGTCT GTGTGCTGTTTGAAAATAAATCTTAGTGTTCAAAACAAAATGAAACAAAAAAAAAAATGA TAAAAAAAAAAAAAAAA >OriGene 5' read for NM_139350 unedited
CCCAGTCGGAATTGTATACGATCATATGGGCGGCCTGCGAATCGGCACCAGGCGGCGTGG AGCGGCAGCCGGTCTGGACGCGCGGCCGGGGCTGGGGGCTGGGAGCGCGGCGCGCAAGAA CTCCCCGCGCGAGAGCGGTCCCTGCCACCGGGCGAGGGCTGCGCCGCGATGGCAGAGATG GGCAGTAAAGGGGTGACGGCGGGAAAGATTGTCATCAACGTGCAGAAGAAGCTCACCCGC GCGCTAGAGTAAGTTCTCCAGAAGCTGGGGAAGGCAGATGAGACCAAGGATGAACAGTTT GAGCAGTGCGTCCAGAATTTCAACAAGCAGCTGACGGAGGGCACCCGGCTGCAGAAGGAG CTCCGGACCTACCTGGGCTCCGTCAAAGCCATGCACGAGGCTTCCAAGAAGCTGAATGAG TGTCTGCAGGAGGTGTATGAGCCCGATTGGCCCGGCGGGATGAGGCAACAAGATCGCAGA GAACAACGACCTGCTGTGGATGGATTACCACCAGAGACTGATGGACCAGCGCTGGTGACC ATGGACACGTACCTGGGCCAGTTTCCCGACATCAAGTTACGCATTGCCAACCGGTGGCTC AGGCCTGGTGGACTACCACAGTGCCCGGCGCCATTACCAGTTCCTTTTAAACCGGCCAAA CGAAGGATGAAGCCCAAAATGGCAAGGCCGAGGAGGAGCTCATCTAAACCTACAGGGTGT TTGAGGAGAATAGAGTGGAATCTGCAGAGGGGCTGCCGTCCCTGTGGAAAAACCGCGTGG GTTTTTAAGTAACCCGTTCCCAAGCATTCGGCCCTGGGGGAAGAACTTCCCAGGGGGATG GGCAGGTTCCACCCCAACTCCANGAAGGGCTGGTTCGGCCTGGGAGAAGAAAACGGGAGC AACACCTTTCGGGCAGGGCTCACCTAAGGCAACCGCCCTG >OriGene 3' read for NM_139350 unedited
NAAATCTTGNACGCGGCCGCAATCTANGATCCGGTTTTTTTTTTTTTTTTTTTTTTTTTA TCATTTTTTTTTTTGTTTCATTTTGTTTTGAACACTAAGATTTATTTTCAAACAGCACAC AGACCGTCTGCGGGGCAGAGCCAGGCTAGGCTGGTGTCTGGGCCCCACCCACAGCAGCTG CCAGGAAAAGAGGACCCTTGCCCGGGTGGCGCGGCCGAAGCTTCAGGCAAGCATGGTGGC TCGGCAGCCCCCAGCCCCGCCCTGCGGCCAGGCACACATGCGGGCACAGGCAGGGGCGCC AGAAACTCAACTAGAGGACACAGCAGCTTCAGGAACACTGGTGAATTCCGCCGGACTTGC CGGGACGCGGCTCTTTGGAAAACGACCTAATCTTTGGGAGAACGCCCCTCTGCCTGGGGG TCTCCTCTTGATTTCCCTTTGCTCTTCAAAAGATGAAAAACGAAAACAAAACAAAAAAAA GAACCACACATTTTTCGGGAGGAGGTGTTCTTCACACGCCCGGAGGCTGCCTGGGCCCCG CCGTCATGGGACCCTCTCAGTGAAGTTCTCGGGGAAGACGCCACGGCACTTCTCCAGCTC CTTGTGCTGGTTCCAGTCGCTCTCCTTCACGCCCATGAGCCAGCCTTCATCCTGCTCTTC AGGGTTCTGGGAAGGGATCACCAGCACCACATCACCAGCCTTGAACTGCAGCTCGTCTGT GTCAGTGGCCGGGTATTCGTGCTGGGCCTGTACCTTGGACATGAAAACTGGGGGGCAGGT TCCAGCGCCCGGGCCCCAATGCCCGCCCTTCCAGGGGGCAATTTCCAGGTGCTGGGGAAG GTCTCCCCCACAAACGCCGGAAAAAAGCTGGAGGCTTGGTTACTTGGCCGCGTCTCCCCT GGGTT |
| Restriction Sites | Please inquire |
| ACCN | NM_139350 |
| Insert Size | 1900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_139350.1, NP_647600.1 |
| RefSeq Size | 2165 bp |
| RefSeq ORF | 1320 bp |
| Locus ID | 274 |
| UniProt ID | O00499 |
| Gene Summary | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in several transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. [provided by RefSeq, Mar 2016] Transcript Variant: This variant (9) lacks five in-frame exons in the coding region, compared to variant 1. Isoform 9, also called BIN1-10, is shorter than isoform 1 and is ubiquitously expressed. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202423 | BIN1 (Myc-DDK-tagged)-Human bridging integrator 1 (BIN1), transcript variant 9 |
CNY 3,656.00 |
|
| RC202423L1 | Lenti ORF clone of Human bridging integrator 1 (BIN1), transcript variant 9, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202423L2 | Lenti ORF clone of Human bridging integrator 1 (BIN1), transcript variant 9, mGFP tagged |
CNY 5,890.00 |
|
| RC202423L3 | Lenti ORF clone of Human bridging integrator 1 (BIN1), transcript variant 9, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202423L4 | Lenti ORF clone of Human bridging integrator 1 (BIN1), transcript variant 9, mGFP tagged |
CNY 6,056.00 |
|
| RG202423 | BIN1 (tGFP-tagged) - Human bridging integrator 1 (BIN1), transcript variant 9 |
CNY 5,256.00 |
