PI 3 Kinase Class 3 (PIK3C3) (AK022653) Human Untagged Clone
CAT#: SC127628
(untagged)-Human cDNA FLJ12591 fis, clone NT2RM4001313, moderately similar to PHOSPHATIDYLINOSITOL 3-KINASE VPS34-LIKE (EC 2.7.1.137)
CNY 5,064.00
CNY 6,270.00
货期*
现货
规格
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经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | hVps34; VPS34; Vps34 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for AK022653, the custom clone sequence may differ by one or more nucleotides
TTATATTTAAGCATGGAGATGATTTACGTCAAGATCAACTTATTCTTCAAATCATTTCACTCATGGACAA GCTGTTACGGAAAGAAAATCTGGACTTGAAATTGACACCTTATAAGGTGTTAGCCACCAGTACAAAACAT GGCTTCATGCAGTTTATCCAGTCAGTTCCTGTGGCTGAAGTTCTTGATACAGAGGGAAGCATTCAGAACT TTTTTAGAAAATATGCACCAAGTGAGAATGGGCCAAATGGGATTAGTGCTGAGGTCATGGACACTTACGT TAAAAGCTGTGCTGGATATTGCGTGATCACCTATATACTTGGAGTTGGAGACAGGCACCTGGATAACCTT TTGCTAACAAAAACAGGTAACAATTAATGACTACCAGTAGACATACATTGTATATGTCCATGGTTTTTAC CCCTGAATCTATGTACTAACAAGATAAGTTGCGGCCTGGCGCGGTGGCTCACGCCCGTAATCCCAGCACT TTGGGAGGCCAAGACGGGTGGATCACCTGAGGTTGGGAGTTCGAGACCAGCCTGACCAACATGGAGAAAC CCCGTCTCTACTAAACACACAAAATTTGCCGGGCGTGGTGGTACATGCCTGTAATCCCAACTACTCAGGA GGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCACCATTGCAC TGCAGACTAGGCAACAAGATCAAAACGCCATCTTAGAAAAAAAAAAAAAAAAAAGATGAGTTGCGTAATT GAAGATAAATCAGAGAGTCTTAAAAATTCCTTTAAATGTTACCTTGGAAGAACATTTAGGGAAAGTCCTT TCCCTTTTAAGAATTGCTTTAGTAGTAATCCTACAGATGGTCATTTTGCCCACACTTCTGTACTGGAAAA TGCCTCTTTTTATGGAAAGCCAATAATGGATACAAGTAGCTTAGTCTCTTACTGTATAGCTCTAGTTAGA TTGTTAAAATGTCCTTTCTCTTACAAAGTGTGCTTAATTCACTTTAATATCTACCTTTAATTATTTGCTT TTCCCCTTGGAGTTCTATGGGATAATCATTCTCAGTCCCCTTTGTCCTGACAACTCTTTAGCCCTATGTA TTTATCTTTATGCAGACAGCTTCCAGACTTACAGCTTTTTACCTCAGTCCATTTCATTAACTTCAAATTG AAATATCGAACTGCTTACTTGAAATTGTCATTATATATGGCCAGTTGTAAAAGGTTGTCCTTTCCTCTAC TACCTGCCTAAAACCTGTTTCTCACCTCATTTTTCCATTTCAATAGATAGCAACATCACCTACCCAGTTG TTCAAGCTCTAGACCTCAAAGTCATTCTTAACATGTCTCTTGGCCTCATCTCATATACTGAACCTATTAG CAAATCTTGTCTACTCCTCAACTCCAAAATAGATCATGAAGTTACCCACTGTCTTCATTTTTACTACTTT GACCCCACTTGAAGCAAACAATATATGTTGCCTAAACAATTTGAATGAAACCTGAACCCTTTATTGGGGC CTTGTGGCTTGTCCAGGCAGGCCATTTGTCTGAATGTCAAACCACTCCTGCCTCAGACAAGAGCCTTTGT TGTTTTCTCTTTCTGGAAAGTTATTTATTCAGATCTTTGCAGGGCTGACTTTAGTTATTAAGTTGAAGTT CTAATGGCATCTCTTTAGAGAAGCCCTTTCTAACTCCTTGATCTGTAATAACATATCTGCCCTCTTCCTC CAATGCTCTCTACTTATTACTGTATTGTTTATAGCACTTATCACTAGCTGAAGTTACCTTTTTTGTTTAA TTCAACAACTATTTATTGAACAGCTAGTAGATGCTGGGAATACCAAAGTTAACAGAAGAGACAGAAATCC TTGCTCTCCTAGAGCTTGTTGAGTTCTTATCATCATCTTCTCCCCTTCAGGATGCAAGTTCCATGAGAGC AGGAACCTTTGTCCATTGGGGTTACCCCCATGCCTCTGGACCTTGAACACCACCTAGCTAAAGTGTTCAA TAAATCAGTGTTGAATTAATGATGAATAAATACTTCTGCTCTTC >OriGene 3' read for AK022653 unedited
GTACCAAGCCGCAATCNANAGTCGAGTTTTTTTTTTTTTTTTTTTAAAAGGCGTTTTGAT CTTGTTGCCTAGTCTGCAGTGCAATGGTGCAATCTCGGCTCACTGCAACCTCCGCCTCCC GGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGTTGGGATTACAGGCATGTACCA CCACGCCCGGCAAATTTTGTGTGTTTATTTTATACGGGGTTTCTCCATGTTGGTCAGGCT GGTCTCGAACTCCCAACCTCAGGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATT ACGGGCGTGAGCCACCGCGCCAGGCCGCAACTTATCTTGTTAGTACATAGATTCAGGGGT AAAAACCATGGGCATATACAATGTATGTCTACTGGTAGTCATTAATTGTTACCTGTTTTT GTTAGCAAAAGGTTATCCAGGTGCCTGTCTCCAACTCCAAGTATATAGGTGATCACGCAA TATCCAGCACAGCTTTTAACGTAAGTGTCCATGACCTCAGCACTAATCCCATTTGGCCCA TTCTCACTTGGTGCATATTTTCTAAAAAAGTTCTGAATGCTTCCCTCTGTATCAAGAACT TCAGCCACAGGAACTGACTGGATAAACTGCATGAAGCCATGTTTTGTACTGGTGGCTAAC ACCTTATAAGGTGTCAATTTCAAGTCCAGATTTTCTTTCCGTAACACCTTGTCCATGAGT GAAATGATTTGAAGAATAAGTTGATCTTGACGTAAATCATCTCCATGCTTAAATATAACT GGATATTTGCCTCCATCTTCCGTCTTANAAAACAACTGTGCAGGCATAAAGGCACTCTTA AACAGTGTAGCTTGTTCCCGGAATATTCCTCTAATTNTCACTTGGGGTTTCTAAAGGCAA CGGGATAAGTCCCACATCTGACAAATTATCTTT |
Restriction Sites | NotI-NotI |
ACCN | AK022653 |
Insert Size | 2840 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | AK022653.1 |
RefSeq Size | 2074 bp |
RefSeq ORF | 2074 bp |
Locus ID | 5289 |
Domains | PI3_PI4_kinase |
Protein Families | Druggable Genome |
Protein Pathways | Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, Regulation of autophagy |
Gene Summary | Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123, PubMed:20208530). Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for transport from early to late endosomes (By similarity).[UniProtKB/Swiss-Prot Function] |
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