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PSMC5 (NM_002805) Human Untagged Clone
CAT＃: SC126754
PSMC5 (untagged)-Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1
CNY 3,656.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | p45; p45/SUG; RPT6; S8; SUG-1; SUG1; TBP10; TRIP1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126754 sequence for NM_002805 edited (data generated by NextGen Sequencing)
ATGGCGCTTGACGGACCAGAGCAGATGGAGCTGGAGGAGGGGAAGGCAGGCAGCGGACTC CGCCAATATTATCTGTCCAAGATTGAAGAACTCCAGCTGATTGTGAATGATAAGAGCCAA AACCTCCGGAGGCTGCAGGCACAGAGGAACGAACTAAATGCTAAAGTTCGCCTATTGCGG GAGGAGCTACAGCTGCTGCAGGAGCAGGGCTCCTATGTGGGGGAAGTAGTCCGGGCCATG GATAAGAAGAAAGTGTTGGTCAAGGTACATCCTGAAGGTAAATTTGTTGTAGACGTGGAC AAAAACATTGACATCAATGATGTGACACCCAATTGCCGGGTGGCTCTAAGGAATGACAGC TACACTCTGCACAAGATCCTGCCCAACAAGGTAGACCCATTAGTGTCACTGATGATGGTG GAGAAAGTACCAGATTCAACTTATGAGATGATTGGTGGACTGGACAAACAGATCAAGGAG ATCAAAGAAGTGATCGAGCTGCCTGTTAAGCATCCTGAGCTCTTCGAAGCACTGGGCATT GCTCAGCCCAAGGGAGTGCTGCTGTATGGACCTCCAGGCACTGGGAAGACACTGTTGGCC CGGGCTGTGGCTCATCATACGGACTGTACCTTTATTCGTGTCTCTGGCTCTGAATTGGTA CAGAAATTCATAGGGGAAGGGGCAAGAATGGTGAGGGAGCTGTTTGTCATGGCACGGGAA CATGCTCCATCTATCATCTTCATGGACGAAATCGACTCCATCGGCTCCTCGCGGCTGGAG GGGGGTTCTGGAGGGGACAGTGAAGTGCAGCGCACGATGCTGGAGTTGCTCAACCAGCTC GACGGCTTTGAGGCCACCAAGAACATCAAGGTTATCATGGCTACTAATAGGATTGATATC CTGGACTCGGCACTGCTTCGCCCAGGGCGCATTGACAGAAAAATTGAATTCCCACCCCCC AATGAGGAGGCCCGGCTGGACATTTTGAAGATTCATTCTCGGAAGATGAACCTGACCCGG GGGATCAACCTGAGAAAAATTGCTGAGCTCATGCCAGGAGCATCAGGGGCTGAAGTGAAG GGCGTGTGCACAGAAGCTGGCATGTATGCCCTGCGAGAACGGCGAGTCCATGTCACTCAG GAGGACTTTGAGATGGCAGTAGCCAAGGTCATGCAGAAGGACAGTGAGAAAAACATGTCC ATCAAGAAATTATGGAAGTGA Clone variation with respect to NM_002805.5 655 c=>t >OriGene 5' read for NM_002805 unedited
ATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGAGAGAAGAGGCGC TTGACGGACCAGAGCAGATGGAGCTGGAGGAGGGGAAGGCAGGCAGCGGACTCCGCCAAT ATTATCTGTCCAAGATTGAAGAACTCCAGCTGATTGTGAATGATAAGAGCCAAAACCTCC GGAGGCTGCAGGCACAGAGGAACGAACTAAATGCTAAAGTTCGCCTATTGCGGGAGGAGC TACAGCTGCTGCAGGAGCAGGGCTCCTATGTGGGGGAAGTAGTCCGGGCCATGGATAAGA AGAAAGTGTTGGTCAAGGTACATCCTGAAGGTAAATTTGTTGTAGACGTGGACAAAAACA TTGACATCAATGATGTGACACCCAATTGCCGGGTGGCTCTAAGGAATGACAGCTACACTC TGCACAAGATCCTGCCCAACAAGGTAGACCCATTAGTGTCACTGATGATGGTGGAGAAAG TACCAGATTCAACTTATGAGATGATTGGTGGACTGGACAAACAGATCAAGGAGATCAAAG AAGTGATCGAGCTGCCTGTTAAGCATCCTGAGCTCTTCGAAGCACTGGGCATTGCTCAGC CCAAGGGAGTGCTGCTGTATGGACCTCCAGGCACTGGGAAGACACTGTTGGCCCGGGCTG TGGCTCATATACGGACTGTACCTTTATTCGTGTCTCTGGCTCTGAATTGGTACAGAAATT CTAGGGGAAGGGGCATGAATGGTGAGGGAGCTNGTTGTCATGCACGGGACATGCTCATCT ATATCTCATGACAAATCACTCATCGCTCTCCGCTGAGGGGGGTCTGAGGGCCANTGATGC ACGCACATGCTGATGCTCACACTCGACGCTTGAGCACAGACTCAGGTTATGCTCAA >OriGene 3' read for NM_002805 unedited
CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGACTTGGCCCACAGAGCT TTATTGGAGAGATACACACAAAGGCTGTCCACTCACTTCCATAATTTCTTGATGGACATG TTTTTCTCACTGTCCTTCTGCATGACCTTGGCTACTGCCATCTCAAAGTCCTCCTGAGTG ACATGGACTCGCCGTTCTCGCAGGGCATACATGCCAGCTTCTGTGCACACGCCCTTCACT TCAGCCCCTGATGCTCCTGGCATGAGCTCAGCAATTTTTCTCAGGTTGATCCCCCGGGTC AGGTTCATCTTCCGAGAATGAATCTTCAAAATGTCCAGCCGGGCCTCCTCATTGGGGGGT GGGAATTCAATTTTTCTGTCAATGCGCCCTGGGCGAAGCAGTGCCGAGTCCAGGATATCA ATCCTATTAGTAGCCATGATAACCTTGATGTTCTTGGTGGCCCTCAAAGCCGTCGAGCTG GTTGAGCAACTCCAGCATCGTGCGCTGCACTTCACTGTCCCCTCCAGAACCCCCCTCCAG CCGCGAGGAGCCGATGGAGTCGATTTCGCCCATGAAGATGATAGATGGAGCATGTTCCCG TGCCATGACAAACAAGCTCCTCACCATTCTTTGCCCCTTCCCCTATGAATTTCTGTACCA ATTCAGAGCCCGAGACACGAATAAATGTACAGTCCGTATGATGAGCCCCAACCCCGGCGC AACCAGTGTCTTCCCAGTGCCTGAAAGGCCATACAGCAACACTCCCCTGGGCCTGACCCA AGCCCATGGCTTTAAAAAGCCCCAGAAGCTTAACAGCCAGCTCGACACTTTCTTGACCCC CCTGACCGGTTGTCCAGTCCCACCAAACTTCCAAAGTTGGAACTGGGCACTTCTCCCCCA TTATCATGAAACTAAAGGGCCCACCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002805 |
| Insert Size | 1430 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002805.4, NP_002796.4 |
| RefSeq Size | 1332 bp |
| RefSeq ORF | 1221 bp |
| Locus ID | 5705 |
| UniProt ID | P62195 |
| Domains | AAA, AAA |
| Protein Families | Druggable Genome |
| Protein Pathways | Proteasome |
| Gene Summary | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor
,Chen, T;Laurenzana, EM;Coslo, DM;Chen, F;Omiecinski, CJ;,
Biochem. J.
,PubMed ID 24224465
[PSMC5]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201251 | PSMC5 (Myc-DDK-tagged)-Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1 |
CNY 3,656.00 |
|
| RC201251L1 | Lenti ORF clone of Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC201251L2 | Lenti ORF clone of Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC201251L3 | Lenti ORF clone of Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1, Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC201251L4 | Lenti ORF clone of Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1, mGFP tagged |
CNY 6,056.00 |
|
| RG201251 | PSMC5 (tGFP-tagged) - Human proteasome (prosome, macropain) 26S subunit, ATPase, 5 (PSMC5), transcript variant 1 |
CNY 5,256.00 |
