CCR4 NOT transcription complex subunit 3 (CNOT3) (NM_014516) Human Untagged Clone

CAT#: SC122815

CNOT3 (untagged)-Human CCR4-NOT transcription complex, subunit 3 (CNOT3)



  "NM_014516" in other vectors (6)

CNY 8,280.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
Rabbit Polyclonal Anti-CNOT3 Antibody
    • 50 ug

CNY 4,628.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms IDDSADF; LENG2; NOT3; NOT3H
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_014516 edited
GGACCGGGCCCGGTCAGCTTCCGCGGAGCCATTGGCAGACGCCGTGGCCTCCCTTGAGCC
CCGACCCCCGTCGTCAGAACAACCCCGGGCCCACTCCCCCAACCCCACTTCCGCTTCGCG
CCGCTATCGCGATAGCGCCCGGGCCCGGGGCGCGAGAAAAAGGCGGCGGGCGCTCGCCTC
CCCCGCCTGTCGCGATACGCTCCTCAGCGGCGGCGCCAGCTCCTGTGCGTCCGTCTCCAA
GAGAGTATGAAGAGAGTGCGTCTGTAGGGCAGGGAAGATGGCGGACAAGCGCAAACTCCA
AGGTGAGATTGATCGCTGCCTCAAGAAGGTGTCCGAGGGCGTGGAGCAGTTTGAAGATAT
TTGGCAGAAGCTCCACAATGCAGCCAACGCGAACCAGAAAGAAAAGTATGAGGCTGACCT
AAAGAAGGAGATTAAGAAGCTACAACGGCTGAGGGACCAAATCAAGACATGGGTAGCGTC
CAACGAGATCAAGGACAAGAGGCAGCTTATAGACAACCGCAAGCTCATTGAGACGCAAAT
GGAACGGTTCAAAGTTGTGGAACGAGAGACCAAAACCAAAGCTTACAGCAAAGAGGGCCT
GGGCCTGGCCCAGAAGGTAGATCCTGCCCAGAAGGAGAAGGAAGAGGTTGGCCAGTGGCT
CACGAATACCATCGACACGCTCAACATGCAGGTGGACCAGTTTGAGAGTGAAGTGGAGTC
ACTGTCAGTGCAGACACGCAAGAAGAAGGGCGACAAGGATAAGCAGGACCGGATTGAGGG
CTTGAAGCGGCACATCGAGAAGCACCGCTACCACGTGCGCATGCTAGAGACCATCCTGCG
CATGCTGGACAATGACTCCATCCTCGTTGACGCCATCCGCAAGATCAAGGACGACGTTGA
GTACTATGTTGACTCATCCCAGGACCCCGACTTCGAGGAGAACGAGTTTCTCTACGATGA
CCTGGACCTCGAGGACATTCCACAGGCGCTGGTCGCCACCTCCCCCCCCAGCCACAGCCA
CATGGAGGATGAGATCTTCAACCAGTCCAGCAGCACGCCCACCTCAACCACCTCCAGCTC
TCCCATCCCGCCCAGCCCAGCCAACTGTACCACGGAAAACTCTGAAGATGATAAGAAGAG
GGGACGTTCCACAGACAGTGAAGTCAGCCAGTCTCCAGCCAAAAACGGCTCCAAGCCTGT
CCACAGCAACCAGCACCCTCAGTCCCCAGCTGTGCCGCCCACCTACCCCTCCGGCCCCCC
GCCTGCTGCCTCTGCCTTGAGCACCACTCCTGGCAACAATGGGGTCCCCGCCCCCGCAGC
ACCCCCAAGTGCCCTGGGCCCCAAGGCCAGTCCAGCTCCCAGCCACAACTCGGGCACCCC
TGCTCCCTATGCCCAGGCGGTGGCCCCACCAGCTCCCAGTGGGCCCAGCACGACCCAGCC
CCGGCCCCCCAGCGTCCAGCCTAGCGGAGGCGGAGGCGGCGGCAGCGGAGGCGGAGGGAG
CAGCAGCAGTAGTAACAGCAGTGCCGGTGGAGGGGCTGGCAAGCAGAATGGCGCCACCAG
TTACAGCTCAGTTGTGGCAGACAGCCCGGCAGAGGTGGCTTTGAGCAGCAGTGGGGGCAA
CAATGCCAGCAGCCAGGCCTTGGGCCCCCCTTCCGGCCCCCACAACCCACCTCCCAGCAC
CTCGAAGGAACCCAGTGCGGCAGCCCCAACGGGGGCTGGGGGCGTGGCCCCAGGCTCAGG
GAACAACTCAGGGGGACCCAGCCTCCTGGTGCCACTGCCTGTGAATCCTCCCAGCTCCCC
AACGCCCAGCTTCAGTGATGCCAAGGCAGCCGGTGCCCTGCTCAATGGGCCTCCACAGTT
CAGCACCGCCCCAGAAATCAAGGCCCCTGAGCCTCTGAGCTCCTTGAAGTCCATGGCGGA
ACGGGCAGCCATCAGCTCTGGCATTGAGGACCCTGTGCCAACGCTGCACCTGACCGAGCG
AGACATCATCCTGAGCAGTACATCAGCACCTCCGGCCTCAGCCCAGCCGCCCCTGCAGCT
GTCAGAGGTGAACATACCGCTGTCGCTGGGTGTCTGTCCACTGGGCCCTGTGCCCCTCAC
CAAGGAGCAGCTCTATCAGCAGGCCATGGAAGAGGCCGCCTGGCACCACATGCCTCACCC
CTCTGACTCTGAGCGTATTCGGCAGTACCTCCCCCGGAACCCCTGTCCGACGCCCCCCTA
CCACCACCAGATGCCACCCCCACACTCGGACACTGTGGAATTCTACCAGCGCCTGTCGAC
CGAGACACTCTTCTTCATCTTCTACTATCTGGAGGGCACTAAGGCACAGTATCTGGCAGC
CAAGGCCCTAAAGAAGCAGTCATGGCGATTCCACACCAAGTACATGATGTGGTTCCAGAG
GCACGAGGAGCCCAAGACCATCACTGACGAGTTTGAGCAGGGCACCTACATCTACTTTGA
CTACGAGAAGTGGGGCCAGCGGAAGAAGGAAGGCTTCACCTTTGAGTACCGCTACCTGGA
GGACCGGGACCTCCAGTGACACCGGCCCCTCCCTCTACCCACCCCCTTCCCCTTGCATGC
TGATCCCCCTGCCCAGGTGAGGGCCCTGCCCTGGAAGACTGGAGGGAGGCCCCAAGCCAC
GGGGCATCCCCCTCTCCCAGGAAGCAGGGAGGGGGCCGGGAGGTTTTCCTCTCAGCCCCA
CCCTGGGGGCCCGGGGGCGAGGGCTGCCCCCTCCTCCCCTCCCCAGTGAGGGACATTTTT
TGGTAAACCTATTTTCATTTTGGAAAATATTTATGAATAAATAGTTTTATATGAAAAAAA
AAAAAAAAAAA
>OriGene 5' read for NM_014516 unedited
CGGGTTCGGATTTGTATACGACTCATATAGGCGGCNCGCGATTCCCGGGATATCGTCGAC
CCACGCGTCCGGGACCGGGCCCGGTCAGCTTCCGCGGAGCCATTGGCAGACGCCGTGGCC
TCCCTTGAGCCCCGACCCCCGTCGTCAGAACAACCCCGGGCCCACTCCCCCAACCCCACT
TCCGCTTCGCGCCGCTATCGCGATAGCGCCCGGGCCCGGGGCGCGAGAAAAAGGCGGCGG
GCGCTCGCCTCCCCCGCCTGTCGCGATACGCTCCTCAGCGGCGGCGCCAGCTCCTGTGCG
TCCGTCTCCAAGAGAGTATGAAGAGAGTGCGTCTGTAGGGCAGGGAAGATGGCGGACAAG
CGCAAACTCCAAGGTGAGATTGATCGCTGCCTCAAGAAGGTGTCCGAGGGCGTGGAGCAG
TTTGAAGATATTTGGCAGAAGCTCCACAATGCAGCCAACGCGAACCAGAAAGAAAAGTAT
GAGGCTGACCTAAAGAAGGAGATTAAGAAGCTACAACGGCTGAGGGACCAAATCAAGACA
TGGGTAGCGTCCAACGAGATCAAGGACAAGAGGCAGCTTATAGACCAACCGCAGCTCATT
GAGACGCANATGGAACGGTTCANAGTTGTGGAACGAGAGACCAAAACCAAAGCTTACAGC
ANAGAGGGCCTGGGCCTGGCCCAGAAGGTAGATCCTGCCCAGAAGGAGAANGAAGAGGTT
GGCCAGTGGCTCACGAATACCATCGACACGCTCAACATGCAGGTGGACCAGTTTGAGAGT
GAAGTGGAGTCACTGTCAGTGCAGACACGCAAGAAGAGGGGCGACAGGGATAGCAGACCC
GGATGAGGNCNTTGAGCGCACATCGAGAAGCACGCTACCACGTGCGCATGCTAGAGACAT
CCTGCGCATGCTGGAN
Restriction Sites Please inquire     
ACCN NM_014516
Insert Size 2831 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_014516.2, NP_055331.1
RefSeq Size 2855 bp
RefSeq ORF 2262 bp
Locus ID 4849
UniProt ID O75175
Protein Families Transcription Factors
Protein Pathways RNA degradation
Gene Summary Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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