CCR4 NOT transcription complex subunit 3 (CNOT3) (NM_014516) Human Untagged Clone
CAT#: SC122815
CNOT3 (untagged)-Human CCR4-NOT transcription complex, subunit 3 (CNOT3)
CNY 8,280.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | IDDSADF; LENG2; NOT3; NOT3H |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_014516 edited
GGACCGGGCCCGGTCAGCTTCCGCGGAGCCATTGGCAGACGCCGTGGCCTCCCTTGAGCC CCGACCCCCGTCGTCAGAACAACCCCGGGCCCACTCCCCCAACCCCACTTCCGCTTCGCG CCGCTATCGCGATAGCGCCCGGGCCCGGGGCGCGAGAAAAAGGCGGCGGGCGCTCGCCTC CCCCGCCTGTCGCGATACGCTCCTCAGCGGCGGCGCCAGCTCCTGTGCGTCCGTCTCCAA GAGAGTATGAAGAGAGTGCGTCTGTAGGGCAGGGAAGATGGCGGACAAGCGCAAACTCCA AGGTGAGATTGATCGCTGCCTCAAGAAGGTGTCCGAGGGCGTGGAGCAGTTTGAAGATAT TTGGCAGAAGCTCCACAATGCAGCCAACGCGAACCAGAAAGAAAAGTATGAGGCTGACCT AAAGAAGGAGATTAAGAAGCTACAACGGCTGAGGGACCAAATCAAGACATGGGTAGCGTC CAACGAGATCAAGGACAAGAGGCAGCTTATAGACAACCGCAAGCTCATTGAGACGCAAAT GGAACGGTTCAAAGTTGTGGAACGAGAGACCAAAACCAAAGCTTACAGCAAAGAGGGCCT GGGCCTGGCCCAGAAGGTAGATCCTGCCCAGAAGGAGAAGGAAGAGGTTGGCCAGTGGCT CACGAATACCATCGACACGCTCAACATGCAGGTGGACCAGTTTGAGAGTGAAGTGGAGTC ACTGTCAGTGCAGACACGCAAGAAGAAGGGCGACAAGGATAAGCAGGACCGGATTGAGGG CTTGAAGCGGCACATCGAGAAGCACCGCTACCACGTGCGCATGCTAGAGACCATCCTGCG CATGCTGGACAATGACTCCATCCTCGTTGACGCCATCCGCAAGATCAAGGACGACGTTGA GTACTATGTTGACTCATCCCAGGACCCCGACTTCGAGGAGAACGAGTTTCTCTACGATGA CCTGGACCTCGAGGACATTCCACAGGCGCTGGTCGCCACCTCCCCCCCCAGCCACAGCCA CATGGAGGATGAGATCTTCAACCAGTCCAGCAGCACGCCCACCTCAACCACCTCCAGCTC TCCCATCCCGCCCAGCCCAGCCAACTGTACCACGGAAAACTCTGAAGATGATAAGAAGAG GGGACGTTCCACAGACAGTGAAGTCAGCCAGTCTCCAGCCAAAAACGGCTCCAAGCCTGT CCACAGCAACCAGCACCCTCAGTCCCCAGCTGTGCCGCCCACCTACCCCTCCGGCCCCCC GCCTGCTGCCTCTGCCTTGAGCACCACTCCTGGCAACAATGGGGTCCCCGCCCCCGCAGC ACCCCCAAGTGCCCTGGGCCCCAAGGCCAGTCCAGCTCCCAGCCACAACTCGGGCACCCC TGCTCCCTATGCCCAGGCGGTGGCCCCACCAGCTCCCAGTGGGCCCAGCACGACCCAGCC CCGGCCCCCCAGCGTCCAGCCTAGCGGAGGCGGAGGCGGCGGCAGCGGAGGCGGAGGGAG CAGCAGCAGTAGTAACAGCAGTGCCGGTGGAGGGGCTGGCAAGCAGAATGGCGCCACCAG TTACAGCTCAGTTGTGGCAGACAGCCCGGCAGAGGTGGCTTTGAGCAGCAGTGGGGGCAA CAATGCCAGCAGCCAGGCCTTGGGCCCCCCTTCCGGCCCCCACAACCCACCTCCCAGCAC CTCGAAGGAACCCAGTGCGGCAGCCCCAACGGGGGCTGGGGGCGTGGCCCCAGGCTCAGG GAACAACTCAGGGGGACCCAGCCTCCTGGTGCCACTGCCTGTGAATCCTCCCAGCTCCCC AACGCCCAGCTTCAGTGATGCCAAGGCAGCCGGTGCCCTGCTCAATGGGCCTCCACAGTT CAGCACCGCCCCAGAAATCAAGGCCCCTGAGCCTCTGAGCTCCTTGAAGTCCATGGCGGA ACGGGCAGCCATCAGCTCTGGCATTGAGGACCCTGTGCCAACGCTGCACCTGACCGAGCG AGACATCATCCTGAGCAGTACATCAGCACCTCCGGCCTCAGCCCAGCCGCCCCTGCAGCT GTCAGAGGTGAACATACCGCTGTCGCTGGGTGTCTGTCCACTGGGCCCTGTGCCCCTCAC CAAGGAGCAGCTCTATCAGCAGGCCATGGAAGAGGCCGCCTGGCACCACATGCCTCACCC CTCTGACTCTGAGCGTATTCGGCAGTACCTCCCCCGGAACCCCTGTCCGACGCCCCCCTA CCACCACCAGATGCCACCCCCACACTCGGACACTGTGGAATTCTACCAGCGCCTGTCGAC CGAGACACTCTTCTTCATCTTCTACTATCTGGAGGGCACTAAGGCACAGTATCTGGCAGC CAAGGCCCTAAAGAAGCAGTCATGGCGATTCCACACCAAGTACATGATGTGGTTCCAGAG GCACGAGGAGCCCAAGACCATCACTGACGAGTTTGAGCAGGGCACCTACATCTACTTTGA CTACGAGAAGTGGGGCCAGCGGAAGAAGGAAGGCTTCACCTTTGAGTACCGCTACCTGGA GGACCGGGACCTCCAGTGACACCGGCCCCTCCCTCTACCCACCCCCTTCCCCTTGCATGC TGATCCCCCTGCCCAGGTGAGGGCCCTGCCCTGGAAGACTGGAGGGAGGCCCCAAGCCAC GGGGCATCCCCCTCTCCCAGGAAGCAGGGAGGGGGCCGGGAGGTTTTCCTCTCAGCCCCA CCCTGGGGGCCCGGGGGCGAGGGCTGCCCCCTCCTCCCCTCCCCAGTGAGGGACATTTTT TGGTAAACCTATTTTCATTTTGGAAAATATTTATGAATAAATAGTTTTATATGAAAAAAA AAAAAAAAAAA >OriGene 5' read for NM_014516 unedited
CGGGTTCGGATTTGTATACGACTCATATAGGCGGCNCGCGATTCCCGGGATATCGTCGAC CCACGCGTCCGGGACCGGGCCCGGTCAGCTTCCGCGGAGCCATTGGCAGACGCCGTGGCC TCCCTTGAGCCCCGACCCCCGTCGTCAGAACAACCCCGGGCCCACTCCCCCAACCCCACT TCCGCTTCGCGCCGCTATCGCGATAGCGCCCGGGCCCGGGGCGCGAGAAAAAGGCGGCGG GCGCTCGCCTCCCCCGCCTGTCGCGATACGCTCCTCAGCGGCGGCGCCAGCTCCTGTGCG TCCGTCTCCAAGAGAGTATGAAGAGAGTGCGTCTGTAGGGCAGGGAAGATGGCGGACAAG CGCAAACTCCAAGGTGAGATTGATCGCTGCCTCAAGAAGGTGTCCGAGGGCGTGGAGCAG TTTGAAGATATTTGGCAGAAGCTCCACAATGCAGCCAACGCGAACCAGAAAGAAAAGTAT GAGGCTGACCTAAAGAAGGAGATTAAGAAGCTACAACGGCTGAGGGACCAAATCAAGACA TGGGTAGCGTCCAACGAGATCAAGGACAAGAGGCAGCTTATAGACCAACCGCAGCTCATT GAGACGCANATGGAACGGTTCANAGTTGTGGAACGAGAGACCAAAACCAAAGCTTACAGC ANAGAGGGCCTGGGCCTGGCCCAGAAGGTAGATCCTGCCCAGAAGGAGAANGAAGAGGTT GGCCAGTGGCTCACGAATACCATCGACACGCTCAACATGCAGGTGGACCAGTTTGAGAGT GAAGTGGAGTCACTGTCAGTGCAGACACGCAAGAAGAGGGGCGACAGGGATAGCAGACCC GGATGAGGNCNTTGAGCGCACATCGAGAAGCACGCTACCACGTGCGCATGCTAGAGACAT CCTGCGCATGCTGGAN |
Restriction Sites | Please inquire |
ACCN | NM_014516 |
Insert Size | 2831 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_014516.2, NP_055331.1 |
RefSeq Size | 2855 bp |
RefSeq ORF | 2262 bp |
Locus ID | 4849 |
UniProt ID | O75175 |
Protein Families | Transcription Factors |
Protein Pathways | RNA degradation |
Gene Summary | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC203795 | CNOT3 (Myc-DDK-tagged)-Human CCR4-NOT transcription complex, subunit 3 (CNOT3) |
CNY 8,272.00 |
|
RC203795L1 | Lenti ORF clone of Human CCR4-NOT transcription complex, subunit 3 (CNOT3), Myc-DDK-tagged |
CNY 10,672.00 |
|
RC203795L2 | Lenti ORF clone of Human CCR4-NOT transcription complex, subunit 3 (CNOT3), mGFP tagged |
CNY 5,890.00 |
|
RC203795L3 | Lenti ORF clone of Human CCR4-NOT transcription complex, subunit 3 (CNOT3), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC203795L4 | Lenti ORF clone of Human CCR4-NOT transcription complex, subunit 3 (CNOT3), mGFP tagged |
CNY 5,890.00 |
|
RG203795 | CNOT3 (tGFP-tagged) - Human CCR4-NOT transcription complex, subunit 3 (CNOT3) |
CNY 9,872.00 |
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