ETV6 (NM_001987) Human Untagged Clone
CAT#: SC118922
ETV6 (untagged)-Human ets variant 6 (ETV6)
CNY 5,488.00
Cited in 2 publications. |
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | TEL; TEL/ABL; THC5 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for NM_001987 edited
GAATTCGGCACGAGGAAACTTCTTAAATGACCGCGTCTGGCTGGCCGTGGAGCCTTTCTG GGTTGGGGAGAGGAAAGGAAAGTGGAAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGT GAGACATGTCTGAGACTCCTGCTCAGTGTAGCATTAAGCAGGAACGAATTTCATATACAC CTCCAGAGAGCCCAGTGCCGAGTTACGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTC GAGCGCTCAGGATGGAGGAAGACTCGATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAA TTTACTGGAGCAGGGATGACGTAGCCCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTT TAAGGCCAATTGACAGCAACACGTTTGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCA AAGAGGACTTTCGCTATCGATCTCCTCATTCAGGTGATGTGCTCTATGAACTCCTTCAGC ATATTCTGAAGCAGAGGAAACCTCGGATTCTTTTTTCACCATTCTTCCACCCTGGAAACT CTATACACACACAGCCGGAGGTCATACTGCATCAGAACCATGAAGAAGATAACTGTGTCC AGAGGACCCCCAGGCCATCCGTGGATAATGTGCACCATAACCCTCCCACCATTGAACTGT TGCACCGCTCCAGGTCACCTATCACGACAAATCACCGGCCTTCTCCTGACCCCGAGCAGC GGCCCCTCCGGTCCCCCCTGGACAACATGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTC AGGGACCCAGGCCGCACCAGGAGAACAACCACCAGGAGTCCTACCCTCTGTCAGTGTCTC CCATGGAGAATAATCACTGCCCAGCGTCCTCCGAGTCCCACCCGAAGCCATCCAGCCCCC GGCAGGAGAGCACACGCGTGATCCAGCTGATGCCCAGCCCCATCATGCACCCTCTGATCC TGAACCCCCGGCACTCCGTGGATTTCAAACAGTCCAGGCTCTCCGAGGACGGGCTGCATA GGGAAGGGAAGCCCATCAACCTCTCTCATCGGGAAGACCTGGCTTACATGAACCACATCA TGGTCTCTGTCTCCCCGCCTGAAGAGCACGCCATGCCCATTGGGAGAATAGCAGACTGTA GACTGCTTTGGGATTACGTCTATCAGTTGCTTTCTGACAGCCGGTACGAAAACTTCATCC GATGGGAGGACAAAGAATCCAAAATATTCCGGATAGTGGATCCCAACGGACTGGCTCGAC TGTGGGGAAACCATAAGAACAGAACAAACATGACCTATGAGAAAATGTCCAGAGCCCTGC GCCACTACTACAAACTAAACATTATCAGGAAGGAGCCAGGACAAAGGCTTTTGTTCAGGT TTATGAAAACCCCAGATGAAATCATGAGTGGCCGAACAGACCGTCTGGAGCACCTAGAGT CCCAGGAGCTGGATGAACAAATATACCAAGAAGATGAATGCTGAAGGAACCAACAGTCCA CCTCAGCGGGCCAGCAGCCCAGGGAACCCCTGCCCACCAGGATTGCTGGAAGTGTGACGG AGCAGGCGGGCTGAGGAGAGTGGAAAAGGAAGCGACCCAGAAATGGCAGGGACACTTCTC TTGCAGACCAAGAGGGACCCTGGAGCACCTTAGACAAACTACCCAGCACAGGCGGGGCTG GAATTCTGGCGGAGGGCACGAGCCTGGGACTCCATGTCACGTTTCCTTCTGATTTGGAAT CTCTCCATCTGTAATTCCTCACCCTCACCCTTCCACCGTTGTTAGTATCATGGTGTTTTT GTTTTTGTTTTTGTTTTAAGAACCTGCAGTTTGACTCTTCATCGTTCATCTAGGGGAAGA CATCTGATGTTGTTTTCCTATGGAAATATATATCTATTATATATATATATTTTTTGCAAA TCTCACAAAGTGCGGCAAGCCCAGCTGGTCAGGAAAGAGAATACTTGCAGAGGGGTTCAG GTTCCTCTTTTTCCTGCCACGTGGATCAGGTCTGTTCCTGTTACTGTTGGGTCTTGGCTG AAAAAAAAAAAATGXXXXXXXXXXXXXXXXXXXXXXCTCGAC >OriGene 5' read for NM_001987 unedited
GTCATACTTTGTATACGACTCATATAGGCGGCCGCNGAATTCGCACGAGGAAACTTCTTA AAGGACCGCGTCTGGCTGGCCGTGGAGCCTTTCTGGGTTGGGGAGAGGAAAAGGAAGTGG AAAAAACCTGAGAACTTCCTGATCTCTCTCGCTGTGAGACATGTCTGAGACTCCTGCTCA GTGTAGCATTAAGCAGGAACGAATTTCATATACACCTCCAGAAAGCCCAGTGCCGAGTTA CGCTTCCTCGACGCCACTTCATGTTCCAGTGCCTCGAGCGCTCAGGATGGAGGAAGACTC GATCCGCCTGCCTGCGCACCTGCGCTTGCAGCCAATTTACTGGAGCAGGGATGACGTAGC CCAGTGGCTCAAGTGGGCTGAAAATGAGTTTTCTTTAAGGCCAATTGACAGCAACACGTT TGAAATGAATGGCAAAGCTCTCCTGCTGCTGACCAAAGAGGACTTTCGCTATCGATCTCC TCATTCAGGTGATGTGCTCTATGAACTCCTTCAGCATATTCTGAAGCAGAGGAAACCTCG GATTCTTTTTTCACCATTCTTCCACCCTGGAAACTCTATACACACACAGCCGGAGGTCAT ACTGCATCAGAACCATGAAGAAGATAACTGTGTCCAGAGGACCCCCAGGCCATCCGTGGA TAATGTGCACCATAACCCTCCCACCTTGAACTGTTGCACCGCTCCAGGTCACCTATCACG ACAAATCACCGGCCTTCTCCTGACCCCGAGCAGCAGCCCCCTCAGTCCCCCCTGGACACA TGATCCGCCGCCTCTCCCCGGCTGAGAGAGCTCATGGGACCCAGCCGCACCAGAGAACAT CACCAGGAGTCCTACCCTCTGTCAGTGTCTNCATGGGAGATAATCCTGCCCAGCGTCCTT CGAGTCCACCCNGAGCATNCAGCNCNCGGCAGATAGCCAAGCGTGATCAACTGATGC >OriGene 3' read for NM_001987 unedited
GAAATCTCCTTTTCATGTTACTTTTTTAAAACCTTTTTTTTTTTTCAGCCAANACCCAAC AGTAACAGGAACAGACCTGATCCACGTGGCAGGAAAAAGAGAACCTGAACCCCTCTGCAA GTATTCTCTTTCCTGACCAGCTGGGCTTGCCGCACTTTGTGAGATTTGCAAAAAATATAT ATATATAATAGATATATANTTTCCATTAGGAAAACAACATCAGATGTCTTCCCCTAGATG AACGATGAAGAGTCAAACTGCAGGTTCTTAAAACAAAAACAAAAACAAAAACACCATGAT ACTAACAACGGTGGAAGGGTGAGGGTGAGGAATTACAGATGGAGAGATTCCAAATCAGAA GGAAACGTGACATGGAGTCCCAGGCTCGTGCCCTCCGCCAGAATTCCAGCCCCGCCTGTG CTGGGTAGTTTGTCTAAGGTGCTCCAGGGTCCCTCTTGGTCTGCAAGAGAAGTGTCCCTG CCATTTCTGGGTCGCTTCCTTTTCCACTCTCCTCAGCCCGCCTGCTCCGTCACACTTCCA GCAATCCTGGTGGGCAGGGGTTCCCTGGGCTGCTGGCCCGCTGAGGTGGACTGTTGGTTC CTTCAGCATTCATCTTCTTGGTATATTTGTTCATCCAGCTCCTGGGACTCTANGTGCTCC AGACGGTCTGTTCGGCCACTCATGATTTCATCTGGGGGTTTCATAAACCTGAACAAAAGC CNTTTGCCTGGCTCCTTCCTGATAAATGTTANTTTGGAGTAGTGGCGCAAGGCTCTGGAC ATTNTCTCATAGGCATGTTTGTTCTGGTCTTATGGTTCCCACAGTCGAGCACTCCGTGGG GATCACTATCCGGGATATTGGGATCTTGGGCTCCATCGGTGAAGTTTTCTCCCGGCTGTC AAAACACTGATGACGTATTCAAACC |
Restriction Sites | NotI-NotI |
ACCN | NM_001987 |
Insert Size | 2240 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001987.3, NP_001978.1 |
RefSeq Size | 5992 bp |
RefSeq ORF | 1359 bp |
Locus ID | 2120 |
UniProt ID | P41212 |
Domains | ETS, SAM_PNT |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Dorso-ventral axis formation |
Gene Summary | This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
---|
ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation.
,null,
Nature cell biology
,PubMed ID 36658219
[ETV6]
|
Mediator Kinase Inhibition Further Activates Super-Enhancer Associated Genes in AML
,null,
Nature
,PubMed ID 26416749
[ETV6]
|
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208185 | ETV6 (Myc-DDK-tagged)-Human ets variant 6 (ETV6) |
CNY 5,488.00 |
|
RC208185L1 | Lenti ORF clone of Human ets variant 6 (ETV6), Myc-DDK-tagged |
CNY 7,888.00 |
|
RC208185L2 | Lenti ORF clone of Human ets variant 6 (ETV6), mGFP tagged |
CNY 5,890.00 |
|
RC208185L3 | Lenti ORF clone of Human ets variant 6 (ETV6), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC208185L4 | Lenti ORF clone of Human ets variant 6 (ETV6), mGFP tagged |
CNY 7,888.00 |
|
RG208185 | ETV6 (tGFP-tagged) - Human ets variant 6 (ETV6) |
CNY 7,088.00 |