NIPP1 (PPP1R8) (NM_138558) Human Untagged Clone

CAT#: SC109604

PPP1R8 (untagged)-Human protein phosphatase 1, regulatory (inhibitor) subunit 8 (PPP1R8), transcript variant 2



  "NM_138558" in other vectors (4)

CNY 2,400.00

CNY 2,950.00


货期*
现货

规格
    • 10 ug

Cited in 1 publication.

Product images

经常一起买 (4)
PPP1R8 mouse monoclonal antibody, clone OTI4E5 (formerly 4E5)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ARD-1; ARD1; NIPP-1; NIPP1; PRO2047
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_138558 edited
AGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTC
AGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGCAAGATGGCG
GCAGCCGCGAACTCCGGCTCTAGCCTCCCGCTGTTCGACTGCCCAACCTGGGCAGGTAAG
CCCCCTCCCGGTTTACATCTGGATGTAGTCAAAGGAGACAAACTAATTGAGAAACTGATT
ATTGATGAGAAGAAGTATTACTTATTTGGGAGAAACCCTGATTTGTGTGACTTTACCATT
GACCACCAGTCTTGCTCTCGGGTCCATGCTGCACTTGTCTACCACAAGCATCTGAAGAGA
GTTTTCCTGATAGATCTCAACAGTACACACGGCACTTTCTTGGGTCACATTCGGTTGGAA
CCTCACAAGCCTCAGCAAATTCCCATCGATTCCACGGTCTCATTTGGCGCATCCACAAGG
GCATACACTCTGCGCGAGAAGCCTCAGACATTGCCATCGGCTGTGAAAGGAGATGAGAAG
ATGGGTGGAGAGGATGATGAACTCAAGGGCTTACTGGGGCTTCCAGAGGAGGAAACTGAG
CTTGATAACCTGACAGAGTTCAACACTGCCCACAACAAGCGGATTTCTACCCTTACCATT
GAGGAGGGAAATCTGGACATTCAAAGACCAAAGAGGAAGAGGAAGAACTCACGGGTGACA
TTCAGTGAGGATGATGAGATCATCAACCCAGAGGATGTGGATCCCTCAGTTGGTCGATTC
AGGAACATGGTGCAAACTGCAGTGGTCCCAGTCAAGAAGAAGCGTGTGGAGGGCCCTGGC
TCCCTGGGCCTGGAGGAATCAGGGAGCAGGCGCATGCAGAACTTTGCCTTCAGCGGAGGA
CTCTACGGGGGCCTGCCCCCCACACACAGTGAAGCAGGCTCCCAGCCACATGGCATCCAT
GGGACAGCACTCATCGGTGGCTTGCCCATGCCATACCCAAACCTTGCCCCTGATGTGGAC
TTGACTCCTGTTGTGCCGTCAGCAGTGAACATGAACCCTGCACCAAACCCTGCAGTCTAT
AACCCTGAAGCTGTAAATGAACCCAAGAAGAAGAAATATGCAAAAGAGGCTTGGCCAGGC
AAGAAGCCCACACCTTCCTTGCTGATTTGATATTTTTGGTCATGGAGAA
>OriGene 5' read for NM_138558 unedited
TTTCCCCGCCCGTTGNCGCATAGGGCGGTAGGCGTGTACGGTGGNGAGTCTATATAAGCA
GAGCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAA
TTCGGCACCAGCAAGATGGCGGCAGCCGCGAACTCCGGCTCTAGCCTCCCGCTGTTCGAC
TGCCCAACCTGGGCAGGTAAGCCCCCTCCCGGTTTACATCTGGATGTAGTCAAAGGAGAC
AAACTAATTGAGAAACTGATTATTGATGAGAAGAAGTATTACTTATTTGGGAGAAACCCT
GATTTGTGTGACTTTACCATTGACCACCAGTCTTGCTCTCGGGTCCATGCTGCACTTGTC
TACCACAAGCATCTGAAGAGAGTTTTCCTGATAGATCTCAACAGTACACACGGCACTTTC
TTGGGTCACATTCGGTTGGAACCTCACAAGCCTCAGCAAATTCCCATCGATTCCACGGTC
TCATTTGGCGCATCCACAAGGGCATACACTCTGCGCGAGAAGCCTCAGACATTGCCATCG
GCTGTGAAAGGAGATGAGAAGATGGGTGGAGAGGATGATGAACTCAAGGGCTTACTGGGG
CTTCCAGAGGAGGAAACTGAGCTTGATAACCTGACAGAGTTCAACACTGCCCACAACAAG
CGGATTTCTACCCTTACCATTGAGGAGGGAAATCTGGACATTCAAAGACCAAAGAGGAAG
AGGAAGAACTCACGGGTGACATTCAGTGAGGATGATGAGATCATCAACCCAGAGGATGTG
GATCCCTCAGTTGGTCGATTCANGAACATGGTGCANACTGCAGTGGTCCCAGTCAAGAAA
AAGCGTGTGGNAGGCCCCTGGNCTCCTGGGGCCTGGNAGAATCAGGNAGCANGCGCATGG
CAGACTTTGCCTTCAGCGGAGGACTCTACGGGG
>OriGene 3' read for NM_138558 unedited
TCTTGAACCGCGCCGCTTTCTAGGATCGAGTTTTTCTTTTTTTTTTTTTTTTTTTTTTTG
ACAAAAGTTACGTTTAATTTACAATGTAATAAAGGTTACAGGTAAAAAGCTACACATAAA
GCATGAAAAGGCCTATTACACAAATGTACAAATCTCTGTACAAAGCTTGTATCAATGTTT
CCTAACTTTGTCTCCTATGTTTGTTAGCCAGGTCTAGTCTTGGAGCTCTGAATAACAAGA
GCTCTCAATTGAGGGGGGAAAGAGCCTCCAAACTGACATCTAAAAATTCCTCTTAGAGAC
ACCAGTTACTTCCAAACAAATCTTTTCCTTTTTAATTTGAATTACCCCAACTGGTCATAT
CCTTTGAAAACTGCCTTCATAATACACTTAAAAGTAATGCCTTAGAGTAGAGGACAGTAC
TCTGGAATTAAATAAGAAACTTCAGCAGGAGGAGTGCTCAGGTTTGACAAGAAAAACAGG
TAAATTTCAAACAATACTGTAAGTTAAAACTATAAACCTGTGTCTATGGCACCAGTCACA
GATGAAGGAAAATCGAAATGTTTTCATTCCAACAGGAAGGACAAAAGAGAAAAGCCTAGC
TACTGGACCTCAAAACCACTGACCCAAGGAAACATTTTTTAGTTTAAACCTCAGCTTAAC
TGCAGAATTCTAAGCCTTCTTTTTGATCAAACTGAGATCTATGGCAACCCTTCTGCTACC
CGGGACTTGGAAGGATAGTGAATATAAATTAGGCTCTGGACCCCCAAGGCTGGTGATGCT
ACTGTAACCTCTACAGCTCTGGATTCAACCTGAGGGCCTGGGATATGTGACTTTCATAAA
AATGATCCTAGAAAAGTGGAGAAAAAAGGAGGTAGTGNAAAGCCCTAGAAAGGACCCAGG
CAGTCTATTGTAAAGGATATAGAACCCTTTCTCTACATGCAGTGGTGTGAAAACAGTCTT
TTGGGCTATTCAT
Restriction Sites NotI-NotI     
ACCN NM_138558
Insert Size 2250 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_138558.1, NP_612568.1
RefSeq Size 2691 bp
RefSeq ORF 630 bp
Locus ID 5511
UniProt ID Q12972
Protein Families Druggable Genome, Transcription Factors
Gene Summary This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (2) is the longest transcript and has its first exon longer at the 3' end as compared to that of transcript variant 1. The resulting isoform (beta/delta) uses a different translation start site and is N-terminally truncated as compared to isoform alpha encoded by variant 1. Isoform beta/delta contains protein phosphatase inhibitory activity.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Citations (1)

Other Versions

Customer Reviews 
Loading...