EMA (MUC1) (NM_002456) Human Untagged Clone

CAT#: SC108321

MUC1 (untagged)-Human mucin 1, cell surface associated (MUC1), transcript variant 1



  "NM_002456" in other vectors (6)

CNY 2,400.00

CNY 6,270.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (4)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00


MUC1 (EMA) mouse monoclonal antibody, clone OTI2F6 (formerly 2F6)
    • 100 ul

CNY 1,999.00
CNY 2,700.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ADMCKD; ADMCKD1; ADTKD2; CA 15-3; CD227; EMA; H23AG; KL-6; MAM6; MCD; MCKD; MCKD1; MUC-1; MUC-1/SEC; MUC-1/X; MUC1/ZD; PEM; PEMT; PUM
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC108321 sequence for NM_002456 edited (data generated by NextGen Sequencing)
ATGACACCGGGCACCCAGTCTCCTTTCTTCCTGCTGCTGCTCCTCACAGTGCTTACAGTT
GTTACAGGTTCTGGTCATGCAAGCTCTACCCCAGGTGGAGAAAAGGAGACTTCGGCTACC
CAGAGAAGTTCAGTGCCCAGCTCTACTGAGAAGAATGCTTTGTCTACTGGGGTCTCTTTC
TTTTTCCTGTCTTTTCACATTTCAAACCTCCAGTTTAATTCCTCTCTGGAAGATCCCAGC
ACCGACTACTACCAAGAGCTGCAGAGAGACATTTCTGAAATGTTTTTGCAGATTTATAAA
CAAGGGGGTTTTCTGGGCCTCTCCAATATTAAGTTCAGGCCAGGATCTGTGGTGGTACAA
TTGACTCTGGCCTTCCGAGAAGGTACCATCAATGTCCACGACGTGGAGACACAGTTCAAT
CAGTATAAAACGGAAGCAGCCTCTCGATATAACCTGACGATCTCAGACGTCAGCGTGAGT
GATGTGCCATTTCCTTTCTCTGCCCAGTCTGGGGCTGGGGTGCCAGGCTGGGGCATCGCG
CTGCTGGTGCTGGTCTGTGTTCTGGTTGCGCTGGCCATTGTCTATCTCATTGCCTTGGCT
GTCTGTCAGTGCCGCCGAAAGAACTACGGGCAGCTGGACATCTTTCCAGCCCGGGATACC
TACCATCCTATGAGCGAGTACCCCACCTACCACACCCATGGGCGCTATGTGCCCCCTAGC
AGTACCGATCGTAGCCCCTATGAGAAGGTTTCTGCAGGTAATGGTGGCAGCAGCCTCTCT
TACACAAACCCAGCAGTGGCAGCCACTTCTGCCAACTTGTAG

Clone variation with respect to NM_002456.5
66 g=>a
>OriGene 5' read for NM_002456 unedited
TGGGGNNGCAATCAACTTGNGNATTTTGTNAACACGTTCTTCACTNTCAGGGNCGGCACG
CGCAATTCGGCACCACATCTGTTCTGCCCCCTCCCCACCCATTTCACCACCACCATGACA
CCGGGCACCCAGTCTCCTTTCTTCCTGCTGCTGCTCCTCACAGTGCTTACAGTTGTTACA
GGTTCTGGTCATGCAAGCTCTACCCCAGGTGGAGAAAAGGAGACTTCGGCTACCCAGAGA
AGTTCAGTGCCCAGCTCTACTGAGAAGAATGCTTTGTCTACTGGGGTCTCTTTCTTTTTC
CTGTCTTTTCACATTTCAAACCTCCAGTTTAATTCCTCTCTGGAAGATCCCAGCACCGAC
TACTACCAAGAGCTGCAGAGAGACATTTCTGAAATGTTTTTGCAGATTTATAAACAAGGG
GGTTTTCTGGGCCTCTCCAATATTAAGTTCAGGCCAGGATCTGTGGTGGTACAATTGACT
CTGGCCTTCCGAGAAGGTACCATCAATGTCCACGACGTGNAGACACAGTTCAATCAGTAT
AAAACGGAAGCAGCCTCTCGATATAACCTGACGATCTCAGACGTCAGCGTGAGTGATGTG
CCATTTCCTTTCTCTGGCCCATCTGGGGCTGGGGTCCCAAGCCTGGGGCATCCCCCCTCT
GGGGCTGGGCCTGGGTTCCGGGTTGCCCCTGGCATTGGCTAACCCAATGGCCTTGGGCGT
GCTGTCAAGGCCCCCCAAAAAAAACTCAGGGGCAATTGGAAATTTTTTTCCCCCCGGGGG
AACCCCCCCCCCCCCTTTAGAGGGGTTTCCCCCACTTTAACAAACCCTTTGGGGCGCCTT
GGGGTGCCCCC
>OriGene 3' read for NM_002456 unedited
GGGGGACTTGGGGATGGCAATTCCCATGNCCAGNANAGCACTGGGGCAGGGTCACAGGGA
TGCCACCCGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTT
TTTTTTTTTTTTTTTTTTTGCGCAGTGGGAGACCACGTTTTATTCAGTCCAGTTCAGGAT
CCCCGCTATCTCAGGGCTCTCTGGGCCAGTCCTCCTGGGAGCCCCCACCACAACACTTCC
CAGGCATGAGCCCTCAGGGGCCCACATGAGCTTCCACACACTGAGAAGTGTCCGAGAAAT
TGGTGGGGCCTCTGAAGGAGGCTGTGAGCAGCCCACCTGAACTCCCAGCTCACCAGCCCA
AACAGGGTGCAGGGGCTCTGGCCCTGAAGAACCTGAGTGGAGTGGAATGGCACTGGCTGG
CCACTCAGCTCAGCGGGCGACGTGCCCCTACAAGTTGGCAGAAGTGGCTGCCACTGCTGG
GTTTGTGTAAGAGAGGCTGCTGCCACCATTACCTGCAGAAACCTTCTCATAGGGGCTACG
ATCGGTACTGCTAGGGGGCACATAGCGCCCATGGGTGTGGTAGGTGGGGTACTCGCTCAT
AGGATGGTAGGTATCCCGGGCTGGAAAGATGTCCAGCTGCCCGTAGTTCTTTCGGCGGCA
CTGACAGACAGCCAAGGCAATGAGATAGACAATGGCCAGCGCAACCAGAACACAGACCAG
CACCAGCAGCGCGATGCCCCAGCCTGGCACCCCAGCCCCAGACTGGGCAGAGAAAGGAAA
TGGCACATCACTCACGCTGACGTCTGAGATCGTCAGGTTATATCGAGAGGCTGCTTCCGT
TTTATACTGATTGAACTGTGTCTCCACGTCGTGGACATTGATGGTACCTT
Restriction Sites Please inquire     
ACCN NM_002456
Insert Size 1300 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_002456.4, NP_002447.4
RefSeq Size 1209 bp
RefSeq ORF 822 bp
Locus ID 4582
UniProt ID P15941
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Gene Summary This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
Transcript Variant: This variant (1) represents isoform 1.
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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