alpha Glucosidase II (GANAB) (NM_198334) Human Untagged Clone
CAT#: SC107856
GANAB (untagged)-Human glucosidase, alpha, neutral AB (GANAB), transcript variant 2
CNY 6,920.00
Product images
CNY 6,281.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | G2AN; GIIA; GLUII; PKD3 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC107856 sequence for NM_198334 edited (data generated by NextGen Sequencing)
ATGGCGGCGGTAGCGGCAGTGGCGGCGCGTAGGAGGCGGTCTTGGGCGTCTTTGGTACTG GCTTTTTTAGGGGTCTGCCTGGGGATTACCCTTGCTGTGGATAGAAGCAACTTTAAGACC TGTGAAGAGAGTTCTTTCTGCAAGCGACAGAGAAGCATACGGCCAGGCCTCTCTCCATAC CGAGCCTTGCTGGACTCTCTACAGCTTGGTCCTGATTCCCTCACGGTCCATCTGATCCAT GAGGTCACCAAGGTGTTGCTGGTGCTAGAGCTTCAGGGGCTTCAAAAGAACATGACTCGG TTCAGGATTGATGAGCTGGAGCCTCGGCGACCCCGATACCGTGTACCAGATGTTTTGGTG GCTGATCCACCAATAGCCCGGCTTTCTGTCTCTGGTCGTGATGAGAACAGTGTGGAGTTA ACCATGGCTGAGGGACCCTACAAGATCATCTTGACAGCACGGCCATTCCGCCTTGACCTA CTAGAGGACCGAAGTCTTTTGCTTAGTGTCAATGCCCGAGGACTCTTGGAGTTTGAGCAT CAGAGGGCCCCTAGGGTCTCGCAAGGATCAAAAGACCCAGCTGAGGGCGATGGGGCCCAG CCTGAGGAAACACCCAGGGATGGCGACAAGCCAGAGGAGACTCAGGGGAAGGCAGAGAAA GATGAGCCAGGAGCCTGGGAGGAGACATTCAAAACTCACTCTGACAGCAAGCCGTATGGC CCCATGTCTGTGGGTTTGGACTTCTCTCTGCCAGGCATGGAGCATGTCTATGGGATCCCT GAGCATGCAGACAACCTGAGGCTGAAGGTCACTGAGGGTGGGGAGCCATATCGCCTCTAC AATTTGGATGTGTTCCAGTATGAGCTGTACAACCCAATGGCCTTGTATGGGTCTGTGCCT GTGCTCCTGGCACACAACCCTCATCGCGACTTGGGCATCTTCTGGCTCAATGCTGCAGAG ACCTGGGTTGATATATCTTCCAACACTGCCGGGAAGACCCTGTTTGGGAAGATGATGGAC TACCTGCAGGGCTCTGGGGAGACCCCACAGACAGATGTTCGCTGGATGTCAGAGACTGGC ATCATTGACGTCTTCCTGCTGCTGGGGCCCTCCATCTCTGATGTTTTCCGGCAATATGCT AGTCTCACAGGAACCCAGGCGTTGCCCCCACTCTTCTCCCTCGGCTACCACCAGAGCCGT TGGAACTACCGGGACGAGGCTGATGTGCTGGAAGTGGATCAGGGCTTTGATGATCACAAC CTGCCCTGTGATGTCATCTGGCTAGACATTGAACATGCTGATGGCAAGCGGTATTTCACC TGGGACCCCAGTCGCTTCCCTCAGCCCCGCACCATGCTTGAGCGCTTGGCTTCTAAGAGG CGGAAGCTGGTGGCCATCGTAGACCCCCACATCAAGGTGGACTCCGGCTACCGAGTTCAC GAGGAGCTGCGGAACCTGGGGCTGTATGTTAAAACCCGGGATGGCTCTGACTATGAGGGC TGGTGCTGGCCAGGCTCAGCTGGTTACCCTGACTTCACTAATCCCACGATGAGGGCCTGG TGGGCTAACATGTTCAGCTATGACAATTATGAGGGCTCAGCTCCCAACCTCTTTGTCTGG AATGACATGAACGAACCATCTGTGTTCAATGGTCCTGAGGTCACCATGCTCAAGGATGCC CAGCATTATGGGGGCTGGGAGCACCGGGATGTGCATAACATCTATGGCCTTTATGTGCAC ATGGCGACTGCTGATGGGCTGAGACAGCGCTCTGGGGGCATGGAACGCCCCTTTGTCCTG GCCAGGGCCTTCTTCGCTGGCTCCCAGCGCTTTGGAGCCGTGTGGACAGGGGACAACACT GCCGAGTGGGACCATTTGAAGATCTCTATTCCTATGTGTCTCAGCTTGGGGCTGGTGGGA CTTTCCTTCTGTGGGGCGGATGTGGGTGGCTTCTTCAAAAACCCAGAGCCAGAGCTGCTT GTGCGCTGGTACCAGATGGGTGCTTACCAGCCATTCTTCCGGGCACATGCCCACTTGGAC ACTGGGCGACGAGAGCCATGGCTGTTACCATCTCAGCACAATGATATAATCCGAGATGCC TTGGGCCAGCGATATTCTTTGCTGCCCTTCTGGTACACCCTCTTATATCAGGCCCATCGG GAAGGCATTCCTGTCATGAGGCCCCTGTGGGTGCAGTACCCTCAGGATGTGACTACCTTC AATATAGATGATCAGTACTTGCTTGGGGATGCGTTGCTGGTTCACCCTGTATCAGACTCT GGAGCCCATGGTGTCCAGGTCTATCTGCCTGGCCAAGGGGAGGTGTGGTATGACATTCAA AGCTACCAGAAGCATCATGGTCCCCAGACCCTGTACCTGCCTGTAACTCTAAGCAGTATC CCTGTGTTCCAGCGTGGAGGGACAATCGTGCCTCGATGGATGCGAGTGCGGCGGTCTTCA GAATGTATGAAGGATGACCCCATCACTCTCTTTGTTGCACTTAGCCCTCAGGGTACAGCT CAAGGAGAGCTCTTTCTGGATGATGGGCACACGTTCAACTATCAGACTCGCCAAGAGTTC CTGCTGCGTCGATTCTCATTCTCTGGCAACACCCTTGTCTCCAGCTCAGCAGACCCTGAA GGACACTTTGAGACACCAATCTGGATTGAGCGGGTGGTGATAATAGGGGCTGGAAAGCCA GCAGCTGTGGTACTCCAGACAAAAGGATCTCCAGAAAGCCGCCTGTCCTTCCAGCATGAC CCTGAGACCTCTGTGTTGGTCCTGCGCAAGCCTGGCATCAATGTGGCATCTGATTGGAGT ATTCACCTGCGATAA Clone variation with respect to NM_198334.1 >OriGene 5' read for NM_198334 unedited
AAAACTTGATTTGTATACGACTTACTATAGGCGGCCGCGATTCGGCACGAGGAGCAAACT CTGCACAAAATGGCGGCGGTAGCGGCAGTGGCGGCGCGTAGGAGGCGGTCTTGGGCGTCT TTGGTACTGGCTTTTTTAGGGGTCTGCCTGGGGATTACCCTTGCTGTGGATAGAAGCAAC TTTAAGACCTGTGAAGAGAGTTCTTTCTGCAAGCGACAGAGAAGCATACGGCCAGGCCTC TCTCCATACCGAGCCTTGCTGGACTCTCTACAGCTTGGTCCTGATTCCCTCACGGTCCAT CTGATCCATGAGGTCACCAAGGTGTTGCTGGTGCTAGAGCTTCAGGGGCTTCAAAAGAAC ATGACTCGGTTCAGGATTGATGAGCTGGAGCCTCGGCGACCCCGATACCGTGTACCAGAT GTTTTGGTGGCTGATCCACCAATAGCCCGGCTTTCTGTCTCTGGTCGTGATGAGAACAGT GTGGAGTTAACCATGGCTGAGGGACCCTACAAGATCATCTTGACAGCACGGCCATTCCGC CTTGACCTACTAGAGGACCGAAGTCTTTTGCTTAGTGTCAATGCCCGAGGACTCTTGGAG TTTGAGCATCAGAGGGCCCCTAGGGTCTCGCAAGGATCAAAAGACCCAGCTGAGGGCGAT GGGGCCCAGCCTGAGGAAACACCCAGGGATGGCGACAAGCCAGAGGAGACTCAGGGGAAG GCAGAGAAAGATGAGCCAGGAGCCTGNGAGGAGACATTCAAAACTCACTTCTGACAGCAG CCGTATGGCCCCATGTCTGTGGGTTTGGACTTCTCTCTGCCAGGCATGGAGCATGTCTAT GGGATCCCTGAGCATGCAGACCACCTGAGGCTGAAGGTCACTNGAGGNTGGGGAGCCATA TC >OriGene 3' read for NM_198334 unedited
CCGCGGCCGCAATTTAGAGTCGAGTTTTTTTTCTTTTTTTTTTTTATGGGTTATCCCTTT ATTGTTTCTCCTTTGATCAAAACGTGTCACAGCTGGGAACCAAGAGGAAGTAAAAAAAAT ACCCACAAATATTCCCCGACTCCCCATTAGTCCTCCCCCAACCCCCCACCCAGGGCTTCC AGCCAACCCCGAGCACACATGATCATCTCCCCCCACCCTCAGGCTTCTCCTAGCAATAAA TACAGGTGACCATGATTCACTGAAACCACAACTGATTTCTCCATCTTAAGTGCCCCTCAA AGGGGACAAGAAGGGGGCAAAAGAAGTTTAATGCGCATCCCCTAAGAGGTGTGGAAACGT CTTTCTGCCGAGGGACAGAGGAGGTAGAACTGCCCCTCTAAGAATTGCAGCAGCTCTACA AGGAATCGGGGAGAGGAAAAGGGTAGAATGAGAGGGAAAAGGATGTTCTTTAGCAACCTC ACTCCTTTGATCCATTCATCCTGTCCGGGGTAAGGGGTGGTCCCAGTGTATCGGTGGGGC ATAAAAAGGGGAGTAAAGCCTGGAGGAAGAAATGAAAGGTGGGAGAGCAATCTGGTGGGA GGGAAGGGGAAAAGGAGCCCTAACTCATTGCCCTCATCTTCTTCCAAGAAGTGGCATCAA CATACAAGAGGCATGAATGGATAGACTCTGGGGGGGAGTCAGGGCTCCTAAATAAGGGGA AGAGAAGGNGCGACAAGGGCCCTGTGGGTTNCTGGNNTGTCGTAGTGAATGTGCTCCAGN TAGAGCAACAGGNATGTGGGGGAATGAAGGAAAGAGTNNGTATCATGGAGTGGGAGAGTG NAGGAGATCACNAGAGGGATTNNGAGCCCANGGTCAGCCNTCTCATNCTGCCCAATGGTG GCAGAATCTGGGNTCTANACANCATAAGTGAGTCTGGGGGAGGGCCCGACTNNCAGGCAG AAGAANGATATCTNTCANACTTATGGCTCCCTTNCCTNCCCNTAACCAAACATCCNTGGG NNTTNCGCAGGTGNAACTCNCATCAGAGC |
Restriction Sites | NotI-NotI |
ACCN | NM_198334 |
Insert Size | 4070 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_198334.1, NP_938148.1 |
RefSeq Size | 3887 bp |
RefSeq ORF | 2835 bp |
Locus ID | 23193 |
UniProt ID | Q14697 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Metabolic pathways, N-Glycan biosynthesis |
Gene Summary | This gene encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease. [provided by RefSeq, Jul 2016] Transcript Variant: This variant (2) lacks an in-frame exon, compared to variant 3. The resulting isoform (2, also known as the alpha1 isoform) lacks an internal segment, compared to isoform 3. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC218899 | GANAB (Myc-DDK-tagged)-Human glucosidase, alpha, neutral AB (GANAB), transcript variant 2 |
CNY 6,912.00 |
|
RC218899L3 | Lenti ORF clone of Human glucosidase, alpha; neutral AB (GANAB), transcript variant 2, Myc-DDK-tagged |
CNY 9,030.00 |
|
RC218899L4 | Lenti ORF clone of Human glucosidase, alpha; neutral AB (GANAB), transcript variant 2, mGFP tagged |
CNY 9,030.00 |
|
RG218899 | GANAB (tGFP-tagged) - Human glucosidase, alpha; neutral AB (GANAB), transcript variant 2 |
CNY 8,512.00 |
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