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GPR161 (NM_153832) Human Untagged Clone
CAT＃: SC100531
GPR161 (untagged)-Human G protein-coupled receptor 161 (GPR161), transcript variant 3
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | RE2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC100531 sequence for NM_153832 edited (data generated by NextGen Sequencing)
ATGAGCCTCAACTCCTCCCTCAGCTGCAGGAAGGAGCTGAGTAATCTCACTGAGGAGGAG GGTGGCGAAGGGGGCGTCATCATCACCCAGTTCATCGCCATCATTGTCATCACCATTTTT GTCTGCCTGGGAAACCTGGTCATCGTGGTCACCTTGTACAAGAAGTCCTACCTCCTCACC CTCAGCAACAAGTTCGTCTTCAGCCTGACTCTGTCCAACTTCCTGCTGTCCGTGTTGGTG CTGCCTTTTGTGGTGACGAGCTCCATCCGCAGGGAATGGATCTTTGGTGTAGTGTGGTGC AACTTCTCTGCCCTCCTCTACCTGCTGATCAGCTCTGCCAGCATGCTAACCCTCGGGGTC ATTGCCATCGACCGCTACTATGCTGTCCTGTACCCCATGGTGTACCCCATGAAGATCACA GGGAACCGGGCTGTGATGGCACTTGTCTACATCTGGCTTCACTCGCTCATCGGCTGCCTG CCACCCCTGTTTGGTTGGTCATCCGTGGAGTTTGACGAGTTCAAATGGATGTGTGTGGCT GCTTGGCACCGGGAGCCTGGCTACACGGCCTTCTGGCAGATCTGGTGTGCCCTCTTCCCC TTTCTGGTCATGCTGGTGTGCTATGGCTTCATCTTCCGCGTGGCCAGGGTCAAGGCACGC AAGGTGCACTGTGGCACAGTCGTCATCGTGGAGGAGGATGCTCAGAGGACCGGGAGGAAG AACTCCAGCACCTCCACCTCCTCTTCAGGCAGCAGGAGGAATGCCTTTCAGGGTGTGGTC TACTCGGCCAACCAGTGCAAAGCCCTCATCACCATCCTGGTGGTCCTCGGTGCCTTCATG GTCACCTGGGGCCCCTACATGGTTGTCATCGCCTCTGAGGCCCTCTGGGGGAAAAGCTCC GTCTCCCCGAGCCTGGAGACTTGGGCCACATGGCTGTCCTTTGCCAGCGCTGTCTGCCAC CCCCTGATCTATGGACTCTGGAACAAGACAGTTCGCAAAGAACTACTGGGCATGTGCTTT GGGGACCGGTATTATCGGGAACCATTTGTGCAACGACAGAGGACTTCCAGGCTCTTCAGC ATTTCCAACAGGATCACAGACCTGGGCCTGTCCCCACACCTCACTGCGCTCATGGCAGGT GGACAGCCCCTGGGGCACAGCAGCAGCACGGGGGACACTGGCTTCAGCTGCTCCCAGGAC TCAGGGACAGATATGATGCTGCTTGAGGACTACACGTCTGATGACAACCCTCCCTCTCAC TGCACTTGCCCACCCAAGAGAAGGAGCTCGGTGACATTTGAGGATGAAGTGGAACAAATC AAAGAAGCTGCCAAGAACTCGATTCTTCATGTGAAAGCTGAAGTACACAAGTCCTTGGAC AGTTACGCAGCAAGCTTGGCCAAAGCCATTGAGGCCGAAGCCAAAATCAACTTATTTGGG GAGGAGGCTTTGCCAGGGGTCTTGGTTACAGCACGGACTGTCCCGGGGGGCGGCTTCGGG GGCCGCCGAGGCAGCAGAACTCTTGTGAGCCAGAGGCTGCAGTTGCAGAGCATCGAAGAA GGAGATGTTTTAGCTGCCGAGCAGAGATGA Clone variation with respect to NM_153832.1 >OriGene 5' read for NM_153832 unedited
CTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGCTCAGGC AAAGGTGTGGGGAGAAGCGGTCACGCCCCTCGGCTGGAATCCGTGAGGACCAGCCTGGTG CACTGTGCGTCCTCTGAGAGGTGAAGGAGCACTGTGTGGTCAGAGGGCTGCGAGCTCTCT GTTTGGGTTCCGAGGAAGACAGAATGGGCTGAACTGGAACTGACCTAAATGTCAGCAAGA GGAGGTCTTTTTCAGTGTGCTCAATATGGTCACCAAGCCTGGAAACATAGAGTCTCACCC TGTTGCTTAGGCAGATGGCGCGATCTCGGCTCCTGGGTTCAAGCAATTCTCCTGCCTCAG CCTCCTGAATAGCCGGGATTACAGTCGTCCAGCATGCTCTGCCCACCCCACGCCGAGGTG CACTGACCATGAGCCTCAACTCCTCCCTCAGCTGCAGGAAGGAGCTGAGTAATCTCACTG AGGAGGAGGGTGGCGAAGGGGGCGTCATCATCACCCAGTTCATCGCCATCATTGTCATCA CCATTTTTGTCTGCCTGGGAAACCTGGTCATCGTGGTCACCTTGTACAAGAAGTCCTACC TCCTCACCCTCAGCAACAAGTTCGTCTTCAGCCTGACTCTGTCCAACTTCCTGCTGTCCG TGTTGGTGCTGCCTTTTGTGGTGACGAGCTCCATCCGCNAGGAATGGATCTTTGGTGTAG TGTGGTGCAACTTCTCTGCCCTCCTCTACCTGCTGATCAGCTCTGCCAGCATGCTAACCC TNCGNGTCATTGCCATCGACCGCTACTATGCTGTCCTGTACCCCATGGTGTACCCCATGA AGATCACAGGGNAACCGGGCTGTGATGGCACTTGTCTACATCTGGNCTCACTCGCTCATC GGCTGCCTGCCACCCCTGNTGGNNNTGTCATCCCGTGAGTTNGACGAAGTCAATGGATGT GTGTGGGCTGCTTGGCACCGGAAGCCTGNCTACACNGNCTTCTGGCAGATCTGGTGTGN >OriGene 3' read for NM_153832 unedited
TATGGAACCGCGGCCGCAATCTANNATCGAGTTTTTTTTTTTTTTTTTTGCTTTAGATGC TTCTGGTCCCATCACTGGGACCTAAAAGAACTCACATGTGGTCTCTGGAAATGCTGAAGC TGTGGACTGTAGACATTATTTTCAGTCCTTGTCCTGGTGGCTGCATACCAGATGCTGCTC CTTCCCTGTGTGTGGCCAGCTGTACACAGTGACATGCTCCCAAGGCCGCGGCACAGGCGG TGATGGGAACTCCTCCCCGGGCCAGCCTCTCAGGCTGCAGCCCCACGGCACCCTGAGGCC CTCATCTCTGCTCGGCAGCTAAAACATCTCCTTCTTCGATGCTCTGCAACTGCAGCCTCT GGCTCACAAGAGTTCTGCTGCCTCGGCGGCCCCCGAAGCCGCCCCCCGGGACAGTCCGTG CTGTAACCAAGACCCCTGGCAAAGCCTCCTCCCCAAATAAGTTGATTTTGGCTTCGGCCT CAATGGCTTTGGCCAAGCTTGCTGCGTAACTGTCCAAGGACTTGTGTACTTCAGCTTTCA CATGAAGAATCGAGTTCTTGGCAGCTTCTTTGATTTGTTCCACTTCATCCTCAAATGTCA CCGAGCTCCTTCTCTTGGGTGGGCAAGTGCAGTGAGAGGGAGGGTTGTCATCAGACGTGT AGTCCTCAAGCAGCATCATATCTGTCCCTGAGTCCTGGGAGCAGCTGAAGCCAGTGTCCC CCGTGCTGCTGCTGTGCCCCNAGGGCTGTCCACCTGCCATGAGCGCAGTGAGGTGTGGGG ACAGGCCCAGGTCTGTGATCCTGTTGGAAATGCTGAAGAGCCTGGGAGTCCTCTGTCGTT GCACAAATGGTTCCCGAAATACCCGTCCCAAAGACATGCNCAGTAGTTCTTGCGAACTGT CTTGTTCCAAAGTCATAGATCANGGGGTGGCAAACAAGCGCTGCAAAGGACAGNCATGTG GCCCAGTCCTCCAGCTCGGGGAGAACGAGCTTTTCCCCCGAG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_153832 |
| Insert Size | 2320 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_153832.1, NP_722561.1 |
| RefSeq Size | 2733 bp |
| RefSeq ORF | 1590 bp |
| Locus ID | 23432 |
| UniProt ID | Q8N6U8 |
| Domains | 7tm_1 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| Gene Summary | The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer. [provided by RefSeq, Mar 2017] Transcript Variant: This variant (3) lacks an alternate exon in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The resulting isoform (2) is shorter compared to isoform 1. Variants 2, 3, 8, 9, and 10 all encode the same isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion
,Feigin, ME;Xue, B;Hammell, MC;Muthuswamy, SK;,
Proc. Natl. Acad. Sci. U.S.A.
,PubMed ID 24599592
[GPR161]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215665 | GPR161 (Myc-DDK-tagged)-Human G protein-coupled receptor 161 (GPR161), transcript variant 2 |
CNY 3,936.00 |
|
| RC215665L3 | Lenti-ORF clone of GPR161 (Myc-DDK-tagged)-Human G protein-coupled receptor 161 (GPR161), transcript variant 2 |
CNY 5,890.00 |
|
| RC215665L4 | Lenti-ORF clone of GPR161 (mGFP-tagged)-Human G protein-coupled receptor 161 (GPR161), transcript variant 2 |
CNY 5,890.00 |
|
| RG215665 | GPR161 (tGFP-tagged) - Human G protein-coupled receptor 161 (GPR161), transcript variant 2 |
CNY 5,536.00 |
|
| SC108456 | GPR161 (untagged)-Human G protein-coupled receptor 161 (GPR161), transcript variant 3 |
CNY 3,944.00 |
