Cd44 (NM_001177787) Mouse Untagged Clone
CAT#: MC216250
Cd44 (untagged) - Mouse CD44 antigen (Cd44), transcript variant 6, (10ug)
CNY 6,080.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | AU023126; AW121933; AW146109; HERMES; Ly-24; Pgp-1 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC216250 representing NM_001177787
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACAAGTTTTGGTGGCACACAGCTTGGGGACTTTGCCTCTTGCAGTTGAGCCTGGCACATCCACATC AGCAGATCGATTTGAATGTAACCTGCCGCTACGCAGGTGTATTCCATGTGGAGAAAAATGGCCGCTACAG TATCTCCCGGACTGAGGCAGCTGACCTCTGCCAGGCTTTCAACAGTACCTTACCCACCATGGACCAAATG AAGTTGGCCCTGAGCAAGGGTTTTGAAACATGCAGGTATGGGTTCATAGAAGGAAATGTGGTAATTCCGA GGATTCATCCCAACGCTATCTGTGCAGCCAACCACACAGGAGTATATATCCTCGTCACGTCCAACACCTC CCACTATGACACATATTGCTTCAATGCCTCAGCCCCTCCTGAAGAAGACTGTACATCAGTCACAGACCTA CCCAATTCCTTCGATGGACCGGTTACCATAACTATTGTCAACCGTGATGGTACTCGCTACAGCAAGAAGG GCGAGTATAGAACACACCAAGAAGACATCGATGCTTCAAACATTATAGATGACGATGTCAGCAGCGGCTC CACCATCGAGAAGAGCACCCCAGAAAGCTACATTTTGCACACCTACCTTCCTACTGAACAGCCTACTGGA GATCAGGATGACTCCTTCTTTATCCGGAGCACCTTGGCCACCACACAGAGTCATTCTCAGAACTTCTCTA CATTACATGGAGAGCCGGAAGAAGACGAAAACCATCCAACAACTTCTATTCTGCCATCTAGCACTAAGAG CGGCGCTAAAGATGCAAGAAGAGGTGGAAGTCTTCCCACAGATACAACTACTTCTGTAGAAGGCTACACC TTTCAATACCCAGACACAATGGAAAATGGGACTCTCTTCCCAGTGACCCCTGCTAAAACTGAGGTCTTTG GAGAAACTGAAGTGACTCTTGCTACTGACTCCAACGTTAATGTTGATGGCTCCTTACCAGGAGATCGAGA CTCATCCAAGGACTCCAGGGGGAGTTCCCGCACTGTGACTCATGGATCCGAATTAGCTGGACACTCAAGT GCGAACCAGGACAGTGGAGTGACCACAACTTCTGGTCCTATGAGGAGACCTCAGATTCCAGAATGGCTCA TCATCTTGGCATCTCTCCTGGCACTGGCTCTGATTCTTGCCGTCTGCATCGCGGTCAATAGTAGGAGAAG GTGTGGGCAGAAGAAAAAGCTGGTGATCAACGGTGGCAATGGGACGGTGGAAGACAGGAAACCCAGTGAG CTCAACGGGGAGGCCAGCAAGTCTCAGGAAATGGTGCATTTGGTGAACAAGGAACCATCAGAGACCCCGG ACCAGTGTATGACAGCTGACGAGACCCGGAATCTGCAGAGTGTGGACATGAAGATTGGGGTGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001177787 |
Insert Size | 1395 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_001177787.1, NP_001171258.1 |
RefSeq Size | 4706 bp |
RefSeq ORF | 1395 bp |
Locus ID | 12505 |
UniProt ID | P15379 |
Gene Summary | Cell-surface receptor that plays a role in cell-cell interactions, cell adhesion and migration, helping them to sense and respond to changes in the tissue microenvironment. Participates thereby in a wide variety of cellular functions including the activation, recirculation and homing of T-lymphocytes, hematopoiesis, inflammation and response to bacterial infection. Engages, through its ectodomain, extracellular matrix components such as hyaluronan/HA, collagen, growth factors, cytokines or proteases and serves as a platform for signal transduction by assembling, via its cytoplasmic domain, protein complexes containing receptor kinases and membrane proteases (PubMed:8343954, PubMed:25065622). Such effectors include PKN2, the RhoGTPases RAC1 and RHOA, Rho-kinases and phospholipase C that coordinate signaling pathways promoting calcium mobilization and actin-mediated cytoskeleton reorganization essential for cell migration and adhesion (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (5) lacks several alternate, in-frame, exons, compared to variant 1. The resulting protein (isoform f) is shorter when it is compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG226618 | Cd44 (tGFP-tagged) - Mouse CD44 antigen (Cd44) transcript variant 6, (10ug) |
CNY 5,130.00 |
|
MR226618 | Cd44 (Myc-DDK-tagged) - Mouse CD44 antigen (Cd44), transcript variant 6 |
CNY 5,488.00 |
|
MR226618L3 | Lenti ORF clone of Cd44 (Myc-DDK-tagged) - Mouse CD44 antigen (Cd44), transcript variant 6 |
CNY 6,560.00 |
|
MR226618L4 | Lenti ORF clone of Cd44 (mGFP-tagged) - Mouse CD44 antigen (Cd44), transcript variant 6 |
CNY 7,888.00 |