Cytochrome P450 1A2 (CYP1A2) Mouse Monoclonal Antibody [Clone ID: UMAB105]
CAT#: UM500073CF
Carrier-free (BSA/glycerol-free) CYP1A2 mouse monoclonal antibody, clone UMAB105
Formulation: Standard
View other "UMAB105" antibodies (2)
Need it in bulk or conjugated?
Get a free quote
CNY 4,999.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | UMAB105 |
Applications | IF, IHC, WB |
Recommend Dilution | IHC 1:100 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human CYP1A2 (NP_000752) produced in HEK293T cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 58.2 kDa |
Gene Name | cytochrome P450 family 1 subfamily A member 2 |
Database Link | |
Background | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region. [provided by RefSeq, Jul 2008] |
Synonyms | CP12; P3-450; P450(PA) |
Reference Data | |
Protein Families | Druggable Genome, P450, Transmembrane |
Protein Pathways | Caffeine metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450, Retinol metabolism, Tryptophan metabolism |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |
其它Cytochrome P450 1A2产品