XPF (ERCC4) Mouse Monoclonal Antibody [Clone ID: UMAB22]
CAT#: UM500022CF
Carrier-free (BSA/glycerol-free) XPF mouse monoclonal antibody,clone UMAB22
Formulation: Standard
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Specifications
Product Data | |
Clone Name | UMAB22 |
Applications | 10k-ChIP, IF, IHC |
Recommend Dilution | WB 1:2000, IF 1:100, FLOW 1:100, IHC 1:500 |
Reactivity | Human, Mouse |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Full length human recombinant protein of human XPF (NP_005227) produced in HEK293 cell. |
Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 104.3 kDa |
Gene Name | ERCC excision repair 4, endonuclease catalytic subunit |
Database Link | |
Background | The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6). |
Synonyms | ERCC11; FANCQ; RAD1; XFEPS; XPF |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Nucleotide excision repair |
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