PDGF AA (PDGFA) Rabbit Polyclonal Antibody
CAT#: TA322986
Anti-PDGFA Rabbit Polyclonal Antibody
Size: 25 ul
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
CNY 3,080.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 101-114 amino acids of Human platelet-derived growth factor alpha polypeptide |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | platelet derived growth factor subunit A |
Database Link | |
Background | The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide; where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes; alveolar smooth muscle cells; and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. |
Synonyms | PDGF-A; PDGF1 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Cytokine-cytokine receptor interaction, Focal adhesion, Gap junction, Glioma, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
Documents
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