alpha 2 Macroglobulin (A2M) Sheep Polyclonal Antibody

CAT#: BP611

alpha 2 Macroglobulin (A2M) sheep polyclonal antibody, Ig Fraction



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CNY 4,499.00


货期*
4周

规格
    • 1 ml

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Specifications

Product Data
Applications ELISA, IHC
Recommend Dilution Immunohistochemistry on frozen sections (1:20 - 1:200).
ELISA.
Reactivity Human
Host Sheep
Clonality Polyclonal
Immunogen Native Alpha-2 Macroglobulin
Specificity This antibody detects alpha-2-Macroglobulin.
Formulation PBS, pH 7.2, 0.09 % Sodium Azide
State: Ig Fraction
State: Liquid Ig fraction
Concentration lot specific
Purification Ammonium Sulphate fractionation
Conjugation Unconjugated
Storage Condition Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer. Centrifuge vial before opening. Avoid repeated freezing and thawing.
Gene Name alpha-2-macroglobulin
Background Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes.
Synonyms Alpha-2-M, CPAMD5, Alpha 2 macroglobulin
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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