Mouse Rpap2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rpap2
Locus ID	231571
Kit Components	GA214267G1, Rpap2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214267G2, Rpap2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214267G3, Rpap2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163461, NM_001163462, NM_001289569, NM_001289570, NM_144911, NM_001359916, NM_001359917, NM_001359918
Synonyms	AW060207
Summary	Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.[UniProtKB/Swiss-Prot Function]

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